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The influence of Nematospiroides dubius on subsequent Nippostrongylus brasiliensis infections in mice

Published online by Cambridge University Press:  06 April 2009

D. Conwil Jenkins
D. Conwil Jenkins
Affiliation:
Pharmaceutical Research Laboratories, May & Baker Ltd, Dagenham, Essex
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Extract

The fecundity and longevity of Nippostrongylus brasiliensis was prolonged in mice previously infected with Nematospiroides dubius only when the former developed from the larval stage in those mice. Such worms appeared to be less immunogenic than worms which developed in mice never exposed to N. dubius.

It is proposed that prolonged fecundity and longevity resulted from an adaptation undertaken by the worms in the face of host antibodies which had been developed against the pre-existing N. dubius infection.

Type
Research Article
Information
Parasitology , Volume 71 , Issue 2 , October 1975 , pp. 349 - 355
Copyright
Copyright © Cambridge University Press 1975

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References

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