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Gastrointestinal hormones: environmental cues for Fasciola hepatica?

Published online by Cambridge University Press:  06 April 2009

M. V. K. Sukhdeo  and
S. C. Sukhdeo
M. V. K. Sukhdeo
Affiliation:
Department of Zoology, University of Toronto, 25 Harbord St, Toronto, Ontario, Canada M5S 1A1
S. C. Sukhdeo
Affiliation:
Department of Zoology, University of Toronto, 25 Harbord St, Toronto, Ontario, Canada M5S 1A1
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Summary

The effects of pharmacological concentrations of several gastrointestinal hormones on the rate of sucker activity and the frequency and the amplitude of spontaneous longitudinal muscle contractions have been examined in adult Fasciola hepatica. Caerulein and serum decrease the rate of oral sucker activity; motilin decreases and CCK–PZ increases ventral sucker activity when compared to controls. Caerulein, serum and motilin significantly inhibit the frequency of contractions while bile, caerulein and motilin decrease the amplitude of contractions. These results suggest that F. hepatica can recognize and respond to certain gastrointestinal hormones and there may be adaptive value in these behavioural responses.

Keywords

Fasciola hepaticagastrointestinal hormonesbehaviouradaptation
Type
Research Article
Information
Parasitology , Volume 98 , Issue 2 , April 1989 , pp. 239 - 243
Copyright
Copyright © Cambridge University Press 1989

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