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The develoment of Haemonchus contortus, a nematode parasite of the ovine abomasum, in the laboratory rabbit

Published online by Cambridge University Press:  06 April 2009

C. J. Mapes  and
G. J. Gallie
C. J. Mapes
Affiliation:
Department of Zoology, University of Bristol, and Deportment of Parasitology, Animal Diseases Research Association, Edinburgh
G. J. Gallie
Affiliation:
Department of Zoology, University of Bristol, and Deportment of Parasitology, Animal Diseases Research Association, Edinburgh
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Extract

The development and growth of Haemonchus contortus was studied in the stomach of the laboratory rabbit. Less than 1% of the ensheathed infective larvae givrn to rabbits become established, whereas after exsheathment in vitro under physiological conditions, 20–30% of the larvae administered developed to nthe 4th stage. Following doses of up to 10000 larvae, nearly all worms were lost from the 16th to the 21st day after infection, but after doses of 50000 larvae considerable numbers of 4th-stage larvae were recovered 25 days after infection. No adult worms were recovered and no eggs were found in the faeces. Infection was accompanied by inflammation, haemorrhage, disruption and flattening of the mucus secreting cells and by mononuclear infiltration. No cellular reactions in the immediate vicinity of the nematodes in the mucosa or changes in the pH of the stomach contents were observed.

Type
Research Article
Information
Parasitology , Volume 74 , Issue 3 , June 1977 , pp. 235 - 242
Copyright
Copyright © Cambridge University Press 1977

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