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Association between large strongyle genera in larval cultures – using rare-event Poisson regression

Published online by Cambridge University Press:  04 June 2013

X. CAO ,
A. N. VIDYASHANKAR  and
M. K. NIELSEN
X. CAO
Affiliation:
Department of Statistics, George Mason University, Fairfax, Virginia, USA
A. N. VIDYASHANKAR
Affiliation:
M.H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, Kentucky, USA
M. K. NIELSEN*
Affiliation:
M.H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, Kentucky, USA
*
*Corresponding author: M.H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, Kentucky, USA. E-mail: martin.nielsen@uky.edu
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Summary

Decades of intensive anthelmintic treatment has caused equine large strongyles to become quite rare, while the cyathostomins have developed resistance to several drug classes. The larval culture has been associated with low to moderate negative predictive values for detecting Strongylus vulgaris infection. It is unknown whether detection of other large strongyle species can be statistically associated with presence of S. vulgaris. This remains a statistical challenge because of the rare occurrence of large strongyle species. This study used a modified Poisson regression to analyse a dataset for associations between S. vulgaris infection and simultaneous occurrence of Strongylus edentatus and Triodontophorus spp. In 663 horses on 42 Danish farms, the individual prevalences of S. vulgaris, S. edentatus and Triodontophorus spp. were 12%, 3% and 12%, respectively. Both S. edentatus and Triodontophorus spp. were significantly associated with S. vulgaris infection with relative risks above 1. Further, S. edentatus was associated with use of selective therapy on the farms, as well as negatively associated with anthelmintic treatment carried out within 6 months prior to the study. The findings illustrate that occurrence of S. vulgaris in larval cultures can be interpreted as indicative of other large strongyles being likely to be present.

Keywords

Large strongylesStrongylusTriodontophoruslarval cultureassociationrare event
Type
Research Article
Information
Parasitology , Volume 140 , Issue 10 , September 2013 , pp. 1246 - 1251
Copyright
Copyright © Cambridge University Press 2013 

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