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One-pot solvothermal method to prepare functionalized Fe3O4 nanoparticles for bioseparation

Published online by Cambridge University Press:  28 February 2012

Guoxin Zhang ,
Fengxiang Qie ,
Jianxuan Hou ,
Shizhong Luo ,
Liang Luo ,
Xiaoming Sun  and
Tianwei Tan
Guoxin Zhang
Affiliation:
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029, People’s Republic of China
Fengxiang Qie
Affiliation:
Beijing Key Lab of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, People’s Republic of China
Jianxuan Hou
Affiliation:
Beijing Key Lab of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, People’s Republic of China
Shizhong Luo
Affiliation:
Beijing Key Lab of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, People’s Republic of China
Liang Luo
Affiliation:
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029, People’s Republic of China
Xiaoming Sun*
Affiliation:
State Key Laboratory of Chemical Resource Engineering, Beijing University of Chemical Technology, Beijing, 100029, People’s Republic of China
Tianwei Tan*
Affiliation:
Beijing Key Lab of Bioprocess, College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, 100029, People’s Republic of China
*
a)Address all correspondence to these authors. e-mail: sunxm@mail.buct.edu.cn
b)e-mail: twtan@mail.buct.edu.cn
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Abstract

Surface-functionalized magnetic nanoparticles were prepared by a facile one-pot solvothermal method in ethylene glycol solution. Zeta value, size, and magnetic properties could be well tuned by introducing different functional group molecules. Characterizations, including transmission electronic microscopy, scanning electronic microscopy, thermogravimetric analysis, x-ray powder diffraction and vibrating sample magnetometer, and Fourier transform infrared spectrophotometer demonstrated the efficiency of this simple and general synthesis strategy. The hydrophilic magnetic nanoparticles with various surface functional groups and zeta values were evidenced as excellent candidates for bioseparation by extracting DNA molecules from a model mixture of cell fractures.

Keywords

BiomaterialNanoscaleMagnetic properties
Type
Articles
Information
Journal of Materials Research , Volume 27 , Issue 7 , 14 April 2012 , pp. 1006 - 1013
Copyright
Copyright © Materials Research Society 2012

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