Depression influences particular phases of sexual responsive cycle as well as the forms of sexual behavior, particular aspects of sexual life and its characteristics in comparison to deepen depression. According to gender differences it is possible to assume gender differences of depression impact on particular aspects of sexuality. The depressive syndrome has its own structure thus we suppose the difference in influence of particular symptoms entering to the global state of depression.

The goal of the research is to find out the influence of deepen depression in the whole scale of depressive syndrome on particular aspects of sexual life in men and women.

The influence of particular depressive symptoms was surveyed with 98 hospitalized patients with depression diagnosis. HAMD subscales were compared to the changes in desire, the ability to arouse and the coital readiness and ASEX questionnaire was used to measure the global changes of sexual function. Gender differences were studied as well.

By statistical analysis the significant influence of anxiety, circadian changes, factor of retardation, sleep quality and body weight changes on the state of sexual function was found out in men. Different influence of particular depression symptoms on phases of sexual responsive cycle was confirmed. Significant influence of anxiety and factor of retardation in HAMD on the state of sexual functions was showed in women. The research confirmed the gender differences.

The research confirmed the need of detailed research of influence of particular depressive symptoms on the global sexual state of depressive patients concerning gender differences.