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Quantitative EEG findings in patients with subcortical vascular encephalopathy

Published online by Cambridge University Press:  16 April 2020

A Primavera  and
P Novello
A Primavera
Affiliation:
Department of Neurology, University of Genoa, Via De Toni 5, 16132Genoa, Italy
P Novello
Affiliation:
Department of Neurology, University of Genoa, Via De Toni 5, 16132Genoa, Italy
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Summary

To characterize the neurophysiological profile of patients with Subcortical Vascular Encephalopathy (SVE) we compared the quantified electroencephalogram (qEEG) of 15 consecutive patients, demented and non-demented, with leukoaraiosis and multiple lacunar infarcts on tomographic scan and magnetic resonance investigation, with those of 30 patients with Alzheimer’s disease (AD) and 30 controls. The investigation was carried out using an EEG fast Fourier transform program, and the data obtained were transformed into mean frequency (MF), calculated in the left occipital derivation, and in percent difference (PD), calculated in eight derivations. The data obtained were compared with the scores of the mini-mental state examination (MMS). The results demonstrate that the patients with SVE displayed a different qEEG pattern in comparison with AD patients and controls, with a prevalence of EEG slowing in frontal derivations, and with good correlation between PD values and MMS scores. The qEEG may detect subtle and/or early changes in patients with SVE. The use of adequate spectral parameters may give valuable data for a better classification of dementia syndromes.

Keywords

qEEGvascular encephalopathymean frequencypercent difference
Type
Original article
Information
European Psychiatry , Volume 7 , Issue 3 , 1992 , pp. 121 - 127
Copyright
Copyright © Elsevier, Paris 1992

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References

Brown, MMHachinski, VC (1989) Vascular dementia Curr Opin Neurol Neurosurgery 2, 78–84Google Scholar
Chotas, HGBorne, JRTesechan, PE (1979) Heuristic techniques in the quantification of the electroencephalogram in renal failure Comp Biomed Res 12, 299–312CrossRefGoogle ScholarPubMed
Coben, LADanziger, WStorandt, M (1985) A longitudinal study of mild senile dementia of Alzheimer type: changes at 1 year and at 2.5 years Electroencephalogr Clin Neurophysiol 61, 101–112CrossRefGoogle ScholarPubMed
Erkinjuntti, TLaaksonen, RSulkava, RSyrjalainen, RPalo, J (1986) Neuropsychological differentiation between normal aging, Alzheimer’s disease and vescular dementia Acta Neurol Scand 74, 393–403CrossRefGoogle Scholar
Folstein, MFFolstein, SEMcHugh, PR (1975) “Mini- Mental state„: a practical method for grading the cognitive state of patients for the clicician J Psychiatr Res 12, 189–198CrossRefGoogle Scholar
Giaquinto, SNolfe, G (1986) The EEG in the normal elderly: a contribution for the interpretation of aging and dementia Electroencephalogr Clin Neurophysiol 63, 540–546CrossRefGoogle ScholarPubMed
Hachinski, VCLassen, NAMarshall, J (1974) Multiinfarct dementia - a cause of mental deterioration in the elderly Lancet ii, 207–209CrossRefGoogle Scholar
Hachinski, VCIliff, LDZilhka, EDu Boulay, GHMcAllister, VLMarshall, JRoss Russell, RWSymon, L (1975) Cerebral blood flow in dementia Arch Neurol 32, 632–637CrossRefGoogle ScholarPubMed
Hachinski, VCPotter, PMerskey, M (1987) Leukoaraiosis Arch Neurol 44, 21–23CrossRefGoogle Scholar
Ishii, NNishiiara, YImamura, T (1986) Why do frontal lobe symptoms predominate in vascular dementia with lacunes? Neurology 36, 340–345CrossRefGoogle ScholarPubMed
Leuchter, AFSpar, JEWalter, DOWeiner, H (1987) Electroencephalographic spectra and coherence in the diagnosis of Alzheimer’s type and multi-infarct dementia Arch Gen Psychiatry 44, 993–998CrossRefGoogle Scholar
McKhann, GDrachman, DFolstein, MKatzman, RPrice, DStadlan, EM (1984) Clinical diagnosis of Alzheimer’s disease: report of the NINCDS-ADRDA work group under the auspices of Department of health and human services. Task force on Alzheimer’s disease Neurology 34, 939–944CrossRefGoogle ScholarPubMed
Nuwer, MRJordan, SEAhn, SS (1987) Evaluation of stroke using EEG frequency analysis and topographic mapping Neurology 37, 1153–1159CrossRefGoogle ScholarPubMed
Oken, BSChiappa, KH (1986) Statistical issues concerning computerized analysis of brainwave topography Ann Neurol 19, 493–494CrossRefGoogle ScholarPubMed
Oken, BSChiappa, KHSalinsky, M (1989) Computerized EEG frequency analysis: sensitivity and specificity in patients with focal lesions Neurology 39, 1281s–1287CrossRefGoogle ScholarPubMed
Pearce, JMS (1983) Dementia in cerebral arterial desease. In: Vascular Disease of the Central Nervous System (Russell, R ed) Churchill Livingstone, London, 361Google Scholar
Penttila, MPartanen, JVSoininen, HRiekkinen, PJ (1985) Quantitative analysis of occipital EEG in different stages of Alzheimer’s disease Electroencephalogr Clin Neurophysiol 60, 1–6CrossRefGoogle ScholarPubMed
Primavera, ANovello, PFinocchi, CCanevari, ECorsello, L (1990) Correlation between mini-mental state examination and quantitative electroencephalography in senile dementia of Alzheimer type Neuropsychobiology 23, 74–78CrossRefGoogle ScholarPubMed
Rao, SMMittenberg, WBernardin, LHaughton, VLeo, GJ (1989) Neuropsychological test findings in subjects with leukoaraiosis Arch Neurol 46, 40–44CrossRefGoogle ScholarPubMed
Roman, GC (1987) Senile dementia of the Binswanger type: a vascular form of dementia in the elderly JAMA 258, 1782–1788CrossRefGoogle ScholarPubMed
Soininen, HPartanen, VJHelkala, ELRiekkinen, PJ (1982) EEG findings in senile dementia and normal aging Acta Neurol (Scand) 65, 59–70CrossRefGoogle ScholarPubMed
Steingart, AHachinski, VCLau, CFox, AJLee, DInzitari, DMerskey, H (1987) Cognitive and neurologic findings in demented patients with diffuse with diffuse white matter lucencies on computed tomographic scan (leuko-araiosis) Arch Neurol 44, 32–39CrossRefGoogle Scholar
Wolfe, NLinn, RBabikian, VLKnoefel, JEAlbert, ML (1990) Frontal system impairment following multiple lacunar infarcts Arch Neurol 47, 129–132CrossRefGoogle ScholarPubMed
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