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Psychotic patients addicted to cannabis and other substances treated with risperidone long acting injectable: Follow-up and reintegration

Published online by Cambridge University Press:  16 April 2020

A. Viala
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
M.N. Vacheron
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
C. Baldacci
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
H. Bardou
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
M. Choudey
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
A. Ekbatani
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
P. Martin
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
L. Masclet
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
I. Rousset
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
O. Ruetsch
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
P.O. Smagghe
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France
F. Caroli
Affiliation:
Département Médico-Psychologique du 14ème Arrondissement, Centre Hospitalier Sainte-Anne, Paris, France

Abstract

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Background and aims:

To investigate patients double diagnosed with psychosis and substance addiction (especially cannabis) treated with risperidone long-acting injectable (RLAI) for their psychosis: characteristics of treatment and psychosocial reintegration.

Methods:

Adults with psychosis were changed to RLAI from their previous medication. Starting doses varied but most patients received 50 mg every two weeks. Patients were regularly followed-up by their psychiatrist from 6 months to more than 2 years after starting treatment with RLAI. A reintegration program adapted to the needs of each patient was started as early as possible with support from all available healthcare services of the department. This program focussed on family, social and professional reintegration.

Results:

Of 60 psychotic patients, 27 patients (mean age 27.7±6.1 years) had a double diagnosis of psychosis and substance addiction (especially cannabis), and were enrolled in this follow-up study. After six months, 26 out of 27 patients had no relapse of substance addiction. Patients participating in the reintegration program were able to live with their family or at home (10 patients), undertake professional education courses (7 patients), or even return to their jobs (3 patients).

Conclusion:

Treatment with RLAI has a positive effect on patients double diagnosed with psychosis and substance addiction (especially cannabis). The association with a reintegration program adapted to the needs of each patient must be started early and maintained for as long as possible in order to have a good clinical outcome, positive impact on the addiction, improve compliance with treatment, and diminish the risk of relapse.

Type
Poster Session 1: Antipsychotic Medications
Copyright
Copyright © European Psychiatric Association 2007
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