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Psychological stress and cortisol secretion in anhedonic alcoholic men

Published online by Cambridge University Press:  16 April 2020

D. Marra ,
D. Warot ,
I. Berlin ,
E. Hispard  and
S. Dally
D. Marra
Affiliation:
Département de Pharmacologie, Hôpital Pitié-Salpêtrière, 47, Bd de l’Hôpital, 75634Paris cedex 13, France
D. Warot*
Affiliation:
Département de Pharmacologie, Hôpital Pitié-Salpêtrière, 47, Bd de l’Hôpital, 75634Paris cedex 13, France
I. Berlin
Affiliation:
Département de Pharmacologie, Hôpital Pitié-Salpêtrière, 47, Bd de l’Hôpital, 75634Paris cedex 13, France
E. Hispard
Affiliation:
Service Médecine Interne, Hôpital Fernand Widal, 200, rue du Fg St Denis, 75010Paris, France
S. Dally
Affiliation:
Service Médecine Interne, Hôpital Fernand Widal, 200, rue du Fg St Denis, 75010Paris, France
*
*Corresponding author. E-mail address: dominique.warot@psl.ap-hop-paris.fr (D. Warot).
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Abstract

We investigated plasma cortisol in a psychological stress paradigm in seven weaned anhedonic alcoholics in comparison with seven age-matched healthy controls. Alcoholics had significantly higher mean plasma cortisol at baseline and no increase following a psychological stress paradigm. Anhedonic alcoholics judged the experimental situation less agreeable than controls. Anhedonic alcoholics may have blunted cortisol response to psychological stress.

Keywords

CortisolAlcoholismAnhedoniaPsychological stress
Type
Short communication
Information
European Psychiatry , Volume 18 , Issue 8 , December 2003 , pp. 415 - 417
Copyright
Copyright © 2003 European Psychiatric Association

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