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Possibilities of Lowering Dementia Level During Transcatheter Treatment of Patients with Atherosclerotic Cerebral Lesions.

Published online by Cambridge University Press:  15 April 2020

I. Maksimovich*
Affiliation:
iterventional neuroangiology, Clinic of Cardiovascular Diseases named after Most Holy John Tobolsky, Moscow, Russia

Abstract

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Introduction

The researchpurpose is the study of brain transcatheter laser revascularization efficacy inthe treatment of cerebral atherosclerosis accompanied by vascular dementia.

Methods

The investigation included 665 patients, 478 (71.87%) men, 187 (28.13%) women, aged40-81 (average age 75) with various types of atherosclerotic lesions of brainvessels accompanied by vascular dementia. All the patients underwent CT, MRI, SG, REG, MUGA.

639(96.09%) patients underwent transcatheter treatment revealing the following: 86patients had macrofocal strokes, 74 – medium focal strokes, 29 – single microfocalstrokes, 36 – multiple microfocal strokes, 273 patients – atheroscleroticlesions without strokes, 98 – arteriolosclerosis, 37 – atheroscleroticparkinsonism, 6 – Binswanger's disease. Of these, CDR-1 – 352 (55.09%), CDR-2 -184 (28.79%), CDR-3 – 103 (16.12%) patients.

Forrevascularization of main intracranial arteries high-energy laser systems were used;for revascularization of distal intracranial branches low-energy laser systemswere used.

Results

Goodimmediate angiographic result – restoration of vascular lumen and patency and collateralrevascularization – was achieved in 628 (98.27%) cases. Goodclinical result (Index Bartels-IB-100): in group CDR-1 – 282 (80.11%), CDR-2 -81 (44.02%), CDR-3 – 9 (8.73%) cases. Satisfactory clinical result (IB-70-80):in group CDR-1 – 53 (15.06%), CDR-2 – 62 (33.70%), CDR-3 – 31 (30.09%) cases. Relatively satisfactory clinical result (IB-50-60): CDR-1 – 17 (4.83%), CDR-2 -41 (22.28%), CDR-3 – 63 (61.16%) cases.

Conclusions

Transcatheterlaser revascularization of cerebral blood vessels allows to significantlyreduce the level of dementia in patients with cerebral atherosclerosis.

Type
Article: 1222
Copyright
Copyright © European Psychiatric Association 2015
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