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Pharmacogenetics – genomics and personalized psychiatry

Published online by Cambridge University Press:  16 April 2020

H.J. Möller  and
D. Rujescu
H.J. Möller
Affiliation:
Ludwig-Maximilians University, Munich, Germany
D. Rujescu*
Affiliation:
Ludwig-Maximilians University, Munich, Germany
*
*Corresponding author. E-mail address: Dan.Rujescu@med.uni-muenchen.de (D. Rujescu).
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Abstract

Pharmacogenetic influences on therapeutic response to e.g. antidepressant or neuroleptic treatment are poorly understood and the lack of efficacy in many of the patients together with side effects can both limit therapy and compliance. Thus the aim of pharmacogenetics and pharmacogenomics is to provide predictive tools for the response to psychopharmacologic agents in the therapy of psychiatric disorders and in that ways to provide a real personalized psychiatry. The following review will summarize the current stage of pharmacogenetics and pharmacogenomics and will critically discuss the possibilities of a personalized medicine.

Keywords

PharmacogeneticsPharmacogenomicsTreatment
Type
Original article
Information
European Psychiatry , Volume 25 , Issue 5: The role of genetics in promoting suicide prevention and the mental health of the population - Nobel Conference: The role of genetics in promoting suicide prevention and the mental health of the population , June 2010 , pp. 291 - 293
Copyright
Copyright © Elsevier Masson SAS 2010

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