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P-935 - Augmentation of Antidepressants With Bright Light Therapyin Patients With Comorbid Depression and Borderline Personality Disorder

Published online by Cambridge University Press:  15 April 2020

J. Prasko
Affiliation:
Department of Psychiatry, University Hospital Olomouc, Medical Faculty, University Palacky Olomouc, Olomouc
M. Brunovsky
Affiliation:
Prague Psychiatric Centre, Prague, Czech Republic
M. Raszka
Affiliation:
Prague Psychiatric Centre, Prague, Czech Republic
J. Vyskocilova
Affiliation:
Prague Psychiatric Centre, Prague, Czech Republic
L. Zavesicka
Affiliation:
Prague Psychiatric Centre, Prague, Czech Republic

Abstract

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Borderline personality disorder (BPD) is typically characterized by instability and impairmed behaviour, affectivity, interpersonal relations and lifestyle. The most common condition comorbid with BPD is a depressive episode. Depression is associated with severe disturbance of the circadian rhythms. This is apparent in depressive patients with BPD. Bright light may be an effective in treatment of seasonal affective disorder. Several studies have suggested antidepressant effects of phototherapy in non-seasonal depressive episodes. The treatment of comorbid depressive disorder and borderline personality disorder (BPD) is usually reported to be less successful than the treatment of patients without personality disorder. Studies describing the use of bright light in depressed patients with comorbid BPD have not been published so far.

Method

The aim of this open study was to assess the effectiveness of a 6-week combined therapy with the application of bright light (10,000 lux, 6:30 to 7:30 a.m. for 6 weeks) added to SSRIs in drug-resistant depressed patients with comorbid BPD who did not respond with improvement to 6-week administration of antidepressants. The study comprised 13 female patients who met the ICD-10 diagnostic criteria for research and the DSM-IV-TR diagnostic criteria for major depression. The participants were regularly evaluated using the CGI, HAMD and MADRS scales and the BDI and BDI self-report inventories.

Results

According to all the assessment instruments, the application of bright white light leads to a significant improvement. However, the results must be interpreted with caution due to the open nature of the study.

Supported

By IGA MZ CR NT 11047-4/2010

Type
Abstract
Copyright
Copyright © European Psychiatric Association 2012
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P-935 - Augmentation of Antidepressants With Bright Light Therapyin Patients With Comorbid Depression and Borderline Personality Disorder
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