The study analyzes effects of using atypical antipsychotic drugs (risperidone and clozapine) as compared with effects of using conventional antipsychotic drugs (haloperidol) in treatment of schizophrenic and schizoaffective disorders. The analysis focuses on assessing quality of life and subjective association with applied treatment in examinees during the administration of a medicament therapy. Level and pace of reducing social dysfunction, as well as of improving quality of life, is measured by Heinrichs-Hanlon-Carpenter scale, while the subjective association with applied antipsychotic treatment in examinees is measured with a specifically designed scale. The study covers 160 examinees split into two groups of 80 - experimental and control. The experimental group's examinees are treated with atypical antipsychotic drugs, and the control groups examinees are treated with conventional antipsychotic drugs. The study encompasses one year of examinee observation with a following frequency: at a beginning of the analysis, after 2 weeks, after 4 weeks, after 8 weeks, after 3 months, after 6 months, after 9 months, and finally after 12 months. Statistical analysis and inter-group comparison of examinees treated with atypical antipsychotic drugs and those treated with conventional antipsychotic drugs followed the observation period.