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P02-325 - Personality Types A/B and D, Cholesterol and Homocystein in Major Depression Compared to PTSD with and Without Depression

Published online by Cambridge University Press:  17 April 2020

R. Topić ,
B. Aukst-Margetić ,
A. Ćima ,
Z. Štimac  and
M. Jakovljević
R. Topić
Affiliation:
Psychiatic Clinic, University Hospital Zagreb, Zagreb, Croatia
B. Aukst-Margetić
Affiliation:
Psychiatic Clinic, University Hospital Zagreb, Zagreb, Croatia
A. Ćima
Affiliation:
Psychiatic Clinic, University Hospital Zagreb, Zagreb, Croatia
Z. Štimac
Affiliation:
Private, Zagreb, Croatia
M. Jakovljević
Affiliation:
Psychiatic Clinic, University Hospital Zagreb, Zagreb, Croatia

Abstract

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Background

Major depression and post-traumatic stress disorder (PTSD) are commonly associated with coronary heart disease (CHD) as well as hyperhomocysteinemia and hypercholesterolemia. Personality types A and D are claimed to be risk factors for CHD.

Aim

To evaluate relations between risky personality types, cholesterol and homocystein serum levels in patients with major depression compared to PTSD patients with and without depression.

Subjects and methods

Personality types A and D, cholesterol and homocysteine level were assessed in 40 patients with major depression and 40 male PTSD patients with and without depression.

Results

Hypercholesterolemia and hyperhomocysteinemia were found more frequently in patients with major depression and PTSD patients with depression than in PTSD without depression. Personality type D (tendency to experience negative emotions and social inhibition) was more frequent among PTSD patients compared to patients with depression, while there was no difference in personality A type (competitiveness, time urgency, aggressiveness and hostility) distribution.

Conclusion

Hypercholesterolemia and hyperhomocysteinemia may be useful clinical markers related to specific treatment options in patients with major depression as well as in PTSD patients.

Type
Psychosomatic disorders / Eating disorders / Somatoform disorders
Information
European Psychiatry , Volume 25 , Issue S1: 18th European Congress of Psychiatry. February 27, March 2, 2010 - Munich, Germany , 2010 , 25-E1024
Copyright
Copyright © European Psychiatric Association 2010
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