Hostname: page-component-5c6d5d7d68-qks25 Total loading time: 0 Render date: 2024-09-01T18:29:43.104Z Has data issue: false hasContentIssue false
  • English
  • Français

Oxcarbazepine as a mood stabiliser.

Published online by Cambridge University Press:  16 April 2020

E.M. VanGent
E.M. VanGent*
Affiliation:
Department of Psychiatry, GGNet, Slingeland Hospital, Doetinchem, The Netherlands

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Carbamazepine as a mood stabiliser: A well-known mood stabiliser. Oxcarbazepine is a metabolite of carbamazepine and works as an anti-epileptic, but it has a more favourable pharmacological profile. Researchers have been studying its mood stabilising effect in bipolar disorders for decades. We have carried out a retrospective study of 7 patient charts.

Results:

7 women; average age: 44 years old; onset of bipolar disorder at the age of 32.

Continous use of oxcarbazepine: 26.1 months and continuous use of the previous mood stabiliser: 20.6 months. The percentage of time spent in euthymia improved from an average of 48% with the previous mood stabiliser to 62% with oxcarbazepine. The percentage of time spent ill both of (hypo)mania and of depression decreased respectively from 24% to 18% and from 25% to 19% with the use of oxcarbazepine. Improvement occurred with 4 of the 7 patients.

Conclusion:

These results are in accordance with the literature. Oxcarbazepine has the advantage of fewer (drug-to drug) interactions than carbamazepine.

Type
Poster Session 2: Bipolar Disorders
Information
European Psychiatry , Volume 22 , Issue S1: 15th AEP Congress - Abstract book - 15th AEP Congress , March 2007 , pp. S261
Copyright
Copyright © European Psychiatric Association 2007
Submit a response

Comments

No Comments have been published for this article.