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Neuropsychological Differences Between Bipolar and Borderline Personality Disorder Patients

Published online by Cambridge University Press:  23 March 2020

I. Michopoulos ,
K. Tournikioti ,
R. Gournellis ,
P. Ferentinos ,
K. Vassilopoulou ,
A. Karavia ,
M. Papadopoulou  and
A. Douzenis
I. Michopoulos
Affiliation:
National and Kapodistrian University of Athens, Medical School, 2nd Department of Psychiatry, “Attikon” Hospital, Athens, Greece
K. Tournikioti
Affiliation:
National and Kapodistrian University of Athens, Medical School, 2nd Department of Psychiatry, “Attikon” Hospital, Athens, Greece
R. Gournellis
Affiliation:
National and Kapodistrian University of Athens, Medical School, 2nd Department of Psychiatry, “Attikon” Hospital, Athens, Greece
P. Ferentinos
Affiliation:
National and Kapodistrian University of Athens, Medical School, 2nd Department of Psychiatry, “Attikon” Hospital, Athens, Greece
K. Vassilopoulou
Affiliation:
National and Kapodistrian University of Athens, Medical School, 2nd Department of Psychiatry, “Attikon” Hospital, Athens, Greece
A. Karavia
Affiliation:
National and Kapodistrian University of Athens, Medical School, 2nd Department of Psychiatry, “Attikon” Hospital, Athens, Greece
M. Papadopoulou
Affiliation:
Ygeias Melathron” Hospital, Department of Neurology, Athens, Greece
A. Douzenis
Affiliation:
National and Kapodistrian University of Athens, Medical School, 2nd Department of Psychiatry, “Attikon” Hospital, Athens, Greece

Abstract

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Introduction

There is a continuing debate about the differences and similarities between bipolar disorder (BD) and borderline personality disorder (BPD).

Objectives

Only few studies have focused on the neuropsychological profile of these two disorders.

Aims

We studied the differences on memory, executive function and inhibitory control between BD and BPD patients.

Methods

Twenty-nine patients with BD in euthymia, 27 patients with BPD and 22 healthy controls matched for age and education were included in the study. All of them were female. BD patients who could also be diagnosed with BPD were excluded from the study. Participants were administered a series of tests from the Cambridge Neuropsychological Test Automated Battery (CANTAB), accessing memory, executive function and inhibitory control.

Results

BD and BPD patients performed worse than controls in general. Significant differences were found in the PAL test; BD patients had 46.71, BPD patients had 36.56 and controls had 15.77 errors (P = 0.004). BPD patients performed worse in the IE/ED set-shifting test; they made 48.16 errors while BD patients made 23.64 and controls 16.14 (P = 0.001). BPD patients performed better in the problem-solving task (SOC), they solved 10.0, BD patients 6.32 and controls 8.32 problems (P < 0.001).

BD and BPD patients had similar performance in the SST inhibition task but worse than controls (P = 0.03).

Conclusions

BD and BPD seem to have differences in neuropsychological performance. BD patients show more deficits in memory learning and problem solving while BPD patients show more deficits in set shifting.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-poster walk: Bipolar disorders – Part 2
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. S208
Copyright
Copyright © European Psychiatric Association 2017
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