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Estimation of cerebral perfusion among patients with eating disorders, anxiety and depressive disorders

Published online by Cambridge University Press:  16 April 2020

A. Banaś
Affiliation:
Psychiatry and Neurotic Disorders, Gdansk, Poland
P. Lass
Affiliation:
Nuclear Medicine Department, Medical University of Gdansk, Gdansk, Poland

Abstract

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Objective

Assessment of the cerebral blood perfusion among patients with eating (ED), anxiety (AD) and depressive disorders (DD), diagnosed according to ICD-10.

Method

57 female and 22 male, aged 17–50 were examined using the Single Photon Emission Computer Tomography (SPECT) and the neuropsychological tests, Benton and Bender. We also used the Beck Depression Inventory, the Hospital Anxiety and Depression Scale, and the Spielberger Self-Evaluation Questionnaire. Electroencephalography was also performed.

Result

In ED, hypoperfusion occurred in 84.21%, and impairment of the central nervous system (CNS), was found in 27.77%, abnormalities in the electroencephalography - in 33.33% of the patients. In AD, hypoperfusion occurred in 72.72%, impairment of CNS - in 40%, abnormalities in EEG - in 48% of patients. In DD, hypoperfusion occurred in 81.48%, impairment of CNS - in 34.61%, abnormalities in EEG - in 38.46% of patients.

Conclusions

Hypoperfusion was observed mostly among patients with ED, mainly in the frontal, parietal areas, and in the thalamus, on the left hand side, similar to DD group. Among patients with AD, hypoperfusion at the left hand side occurred almost three times more frequently than among patients with DD (Chi2 = 6.54, p < .025). Anxiety as a trait was the highest in ED, but not significant. Among patients with AD, anxiety as a trait and as a state were almost at the same level.

Type
P03-532
Copyright
Copyright © European Psychiatric Association 2011
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