Hostname: page-component-77c89778f8-m42fx Total loading time: 0 Render date: 2024-07-18T07:53:02.113Z Has data issue: false hasContentIssue false

EPA-0928 - Diagnosis and Treatment of Depressive Disorders in Alzheimer's Disease

Published online by Cambridge University Press:  15 April 2020

E. Ponomareva*
Affiliation:
Alzheimer disease and Related Disorders Research Center, Mental Health Research Center of RAMS, Moscow, Russia

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Depression (D) in people with Alzheimer's disease (AD) is common. Coexistence of D and ?D has recently become one of the most interesting problems for gerontopsychiatrists due to high frequency of this co-occurrence in clinical picture of ?D and due to difficulties in differentiation between D and dementia in old age. It's important to study an influence of depressive disorders on progression of dementia. Two groups of AD patients with and without symptoms of D were compared. The comparative analysis shows that presence of D correlates with earlier ?D onset, which thought to be a probable trigger factor for AD manifestation or the earliest symptom of developing neurodegeneration. The data showed that D in dementia increased the speed of progression of cognitive decline. Furthermore, presence of D leads to earlier institutionalizing of the patients and increases the mortality rate of patients with senile and presenile types of ?D at the mild and moderate stages of dementia. Selective inhibitor of serotonin reuptake may be considered to treat D with AD. The side effects of tricyclic antidepressants can be harmful for people with AD.

Type
EPW32 - Depression 3
Copyright
Copyright © European Psychiatric Association 2014
Submit a response

Comments

No Comments have been published for this article.