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Effectiveness and implementation of a MUltidisciplinary Lifestyle focused approach in the Treatment of Inpatients with mental illness (MULTI+): a stepped wedge study protocol

Published online by Cambridge University Press:  01 September 2022

M. Van Schothorst ,
N. Den Bleijker ,
I. Hendriksen ,
W. Cahn ,
N. De Vries ,
P. Van Harten  and
J. Deenik
M. Van Schothorst
Affiliation:
GGz Centraal, Scientific Research Department, Amersfoort, Netherlands
N. Den Bleijker*
Affiliation:
GGz Centraal, Scientific Research Department, Amersfoort, Netherlands
I. Hendriksen
Affiliation:
LivIng Active, -, Santpoort-Zuid, Netherlands
W. Cahn
Affiliation:
University Medical Centre Utrecht, Psychiatry, Utrecht, Netherlands
N. De Vries
Affiliation:
Maastricht University, School For Mental Health And Neuroscience, Maastricht, Netherlands
P. Van Harten
Affiliation:
GGz Centraal, Scientific Research Department, Amersfoort, Netherlands
J. Deenik
Affiliation:
GGz Centraal, Scientific Research Department, Amersfoort, Netherlands
*
*Corresponding author.

Abstract

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Introduction

People with mental illness (MI) have a reduced life expectancy compared to the general population, mostly attributable to somatic diseases caused by poor physical health. Modifiable lifestyle factors are increasingly associated with the onset of somatic diseases in people with MI. Despite the increasing evidence for the efficacy of lifestyle interventions there is little change in routine clinical care. This discrepancy is referred to as the implementation gap and has caused a need for effectiveness and implementation research in real-world settings.

Objectives

This study investigates the health outcomes and implementation of a multidisciplinary lifestyle focused approach in treatment of inpatients with mental illness (MULTI+).

Methods

This is an open cohort stepped wedge cluster randomized trial in inpatients psychiatric wards of GGz Centraal. Three clusters are randomly allocated to one of the three pre-defined steps to integrate MULTI+. MULTI+ can be tailored to fit individual psychiatric wards and includes 10 core components aimed at improving lifestyle factors. The primary outcome is to investigate whether there is a greater decrease in the QRISK3 cardiovascular risk score after receiving MULTI+ as compared to treatment as usual. Secondary outcomes include somatic and mental health outcomes, lifestyle factors, and implementation factors.

Results

First results expected in 2022.

Conclusions

To our knowledge, this will be the first large-scale study evaluating the long-term effects of a multidisciplinary, multicomponent approach aimed at improving lifestyle factors. We expect that this approach will increase long-term sustainability and can serve as a potential blueprint for future implementation of lifestyle interventions to improve routine clinical care.

Disclosure

No significant relationships.

Keywords

Health outcomesImplementationmental illnessprotocol
Type
Abstract
Information
European Psychiatry , Volume 65 , Special Issue S1: Abstracts of the 30th European Congress of Psychiatry , June 2022 , pp. S868
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2022. Published by Cambridge University Press on behalf of the European Psychiatric Association
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