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Cognitive complaints in schizophrenia are associated with clinical symptoms and global functioning but not actual cognitive performance

Published online by Cambridge University Press:  16 April 2020

D. Kontis
Affiliation:
1st Psychiatric Department, Psychiatric Hospital of Attica, ‘Dafni’, Athens, Greece
E. Theochari
Affiliation:
1st Psychiatric Department, Psychiatric Hospital of Attica, ‘Dafni’, Athens, Greece
S. Kleisas
Affiliation:
1st Psychiatric Department, Psychiatric Hospital of Attica, ‘Dafni’, Athens, Greece
I. Makris
Affiliation:
1st Psychiatric Department, Psychiatric Hospital of Attica, ‘Dafni’, Athens, Greece
S. Kalogerakou
Affiliation:
Laboratory of Experimental Psychology, 1st Department of Psychiatry, Eginition Hospital, Athens, Greece
H. Frissyra
Affiliation:
Department of Medical Genetics, Agia Sophia Children's Hospital, Athens University Medical School, Athens, Greece
A. Andreopoulou
Affiliation:
1st Psychiatric Department, Psychiatric Hospital of Attica, ‘Dafni’, Athens, Greece
C. Karouzos
Affiliation:
1st Psychiatric Department, Psychiatric Hospital of Attica, ‘Dafni’, Athens, Greece
E. Tsaltas
Affiliation:
Laboratory of Experimental Psychology, 1st Department of Psychiatry, Eginition Hospital, Athens, Greece

Abstract

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Introduction

Although it is well established that patients with schizophrenia demonstrate cognitive impairments, little is known about their complaints concerning their cognition. We investigate the association of these complaints with clinical symptoms, global functioning and cognitive performance.

Method

93 patients with chronic schizophrenia (mean age = 42,59 years, SD = 9,83; mean illness duration = 18,43 years, SD = 11,84) were recruited from one psychiatric department. Their cognitive complaints (Subjective Scale to Investigate Cognition in Schizophrenia-SSTICS), clinical symptoms (Calgary depression scale-CDS, PANSS, GAF), and neuropsychological performance (7 non-verbal CANTAB tests involving psychomotor speed, attention, memory, and executive function and WAIS-III) were assessed at a time that they were able to cooperate with neuropsychological testing. Correlation analyses were performed between SSTICS scores and measures of symptoms, functioning or cognition, using the SPSS.

Results

SSTICS total score positively correlated with CDS total score (Spearman's rho = 0.311, p = 0.03). Positive correlations were also found between the SSTICS items and CDS total score. Similarly, SSTICS total score positively correlated with PANSS total score (Pearson r = 0,294, p = 0.04). PANSS negative and general psychopathology scores (r = 0,219, p = 0.035 and r = 0.333, p = 0.01, respectively), but not PANSS positive scores accounted for this relationship. SSTICS total score negatively correlated with GAF (rho = −0.251, p = 0.017). No significant associations were revealed between SSTICS total scores and PANSS insight item, PANSS cognitive score, CANTAB or WAIS scores.

Conclusions

The complaints of patients with schizophrenia about their cognitive impairments are mostly related to their depressive, negative, general psychopathological symptoms and global functioning, rather than their actual cognitive deficits.

Type
P03-252
Copyright
Copyright © European Psychiatric Association 2011
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