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Clinical Personality Patterns in Patients with Acute Lymphoblastic Leukemia Waiting for Bone Marrow Transplantation

Published online by Cambridge University Press:  23 March 2020

D. Vybornykh ,
S. Khrushchev ,
E. Rasskazova ,
L. Kuzmina ,
E. Parovichnikova  and
A. Tkhostov
D. Vybornykh
Affiliation:
National Research Center for Hematology, Laboratory studying mental and neurological disorders in patients with hematological diseases, Moscow, Russia
S. Khrushchev
Affiliation:
National Research Center for Hematology, Laboratory studying mental and neurological disorders in patients with hematological diseases, Moscow, Russia
E. Rasskazova
Affiliation:
Moscow State University, Mental Health Research Center, Clinical Psychology, Moscow, Russia
L. Kuzmina
Affiliation:
National Research Center for Hematology, Research and clinical department of high-dose chemotherapy and bone marrow transplantation, Moscow, Russia
E. Parovichnikova
Affiliation:
National Research Center for Hematology, Research clinical department of leukemia chemotherapy, hematopoiesis depression and bone marrow transplantation, Moscow, Russia
A. Tkhostov
Affiliation:
Moscow State University, Clinical psychology, Moscow, Russia

Abstract

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Introduction

Personality disorders are rather widespread in oncology settings demanding special attention of clinician. Serious illness threatening person's life as well as severe treatment and side effects lead to specific self-regulatory emotional and cognitive efforts. Personality could both play an important role in this process predicting adjustment and survival and change in line with illness pathogenesis.

Objectives

The personality patterns could be important predictors of operation success and further adjustment for patients with acute lymphoblastic leukemia (ALL) waiting for bone marrow transplantation.

Aim

To reveal personality patterns specific for patients with ALL.

Methods

Twenty-five patients with ALL (11 males, 37.4 ± 9.5 years old) filled Millon Clinical Multiaxial Inventory–III and Big Five Questionnairie–2. Comparison group included 180 people of the same age and gender without history of mental or severe somatic disorders.

Results

Male patients comparing to healthy males were lower on emotional control and higher in negativistic personality pattern (P < .05). Female patients were higher on dynamism but lower in openness to culture and antisocial pattern (P < .05). They rarely expressed patterns of borderline disorder and drug dependence but reported more compulsive traits (P < .05).

Conclusions

Severe illness could increase likelihood of emotion regulation difficulties and passive-aggressive coping in male patients while stimulate activity and compulsive behaviour in females. These patterns should be taken into account in psychological support of patents to bone marrow transplantation.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-Poster Viewing: Oncology and psychiatry
Information
European Psychiatry , Volume 41 , Issue S1: Abstract of the 25th European Congress of Psychiatry , April 2017 , pp. S670
Copyright
Copyright © European Psychiatric Association 2017
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