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A case clozapine induced palilalia

Published online by Cambridge University Press:  16 April 2020

R. Lopes ,
J. Azevedo ,
R. Curral ,
M. Esteves  and
R. Coelho
R. Lopes
Affiliation:
Psychiatry, S. João Hospital, Oporto, Portugal
J. Azevedo
Affiliation:
Psychiatry, S. João Hospital, Oporto, Portugal Psychiatry, Faculty of Medicine - University of Oporto, Oporto, Portugal
R. Curral
Affiliation:
Psychiatry, S. João Hospital, Oporto, Portugal Psychiatry, Faculty of Medicine - University of Oporto, Oporto, Portugal
M. Esteves
Affiliation:
Psychiatry, S. João Hospital, Oporto, Portugal Psychiatry, Faculty of Medicine - University of Oporto, Oporto, Portugal
R. Coelho
Affiliation:
Psychiatry, S. João Hospital, Oporto, Portugal Psychiatry, Faculty of Medicine - University of Oporto, Oporto, Portugal

Abstract

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Introduction

Palilalia is an acquired speech disorder characterized by involuntary and spontaneous repetition of words or phrases two or more time in a row. Palilalia can occur in a variety of disorders including postencephalic parkinsonism, advanced Parkinson disease, as well as in schizophrenia, and in Gilles de la Tourette syndrome. There is one report of palilalia induced by neuroleptics.

Aims

To review the literature related to palilalia. Clinical case: We described a case of a 28 years-old man with refractory schizophrenia that demonstrated palilalia with 300 mg of clozapine.

Discussion

In the patient evaluation we just found unspecific alterations in the electroencephalogram. Palilalia disappeared with lowering doses of clozapine.

Conclusion

Palilalia can have several causes. The appearance of palilalia induced by clozapine is a rare side effect.

Type
P03-57
Information
European Psychiatry , Volume 26 , Issue S2: Abstracts of the 19th European Congress of Psychiatry , March 2011 , pp. 1226
Copyright
Copyright © European Psychiatric Association 2011
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