Skip to main content Accessibility help
×
Home
Hostname: page-component-747cfc64b6-cssqh Total loading time: 0.214 Render date: 2021-06-17T00:35:28.164Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": true, "newCiteModal": false, "newCitedByModal": true, "newEcommerce": true }

Article contents

Cannabinoid hyperemesis syndrome, a treatment discussion

Published online by Cambridge University Press:  23 March 2020

M.J. Gordillo
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
C. Caballero
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
S. Latorre
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
S.V. Boned
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
M. Guisado
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
M. De Almuedo
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
P. Torres
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
M.T. Sanchez
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
E. Contreras
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
A. Fernandez
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
G. Esmeralda
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
E. Sanchez
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
M. Segura
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
C. Torres
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
G. Herrero
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
M. Tur
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain
C. Merino
Affiliation:
Psychiatry unit, Can Misses hospital, Ibiza, Spain

Abstract

Introduction

Cannabinoid hyperemesis syndrome (CHS), is characterized by recurrent episodes of severe nausea and intractable vomiting, preceded by chronic use of cannabis. A pathognomonic characteristic is compulsive bathing in hot water. The resolution of the problem occurs when cannabis use is stopped. However, patients are often reluctant to discontinue cannabis. Treatment with anti-emetic medication is ineffective. Case series suggested haloperidol as a potential treatment. Other antipsychotics as olanzapine has been used as anti-emetic treatment in chemotherapy.

Objectives

To describe three cases of patients with CHS whom showed a successful response to olanzapine, even when, haloperidol had failed.

Aims

To present an alternative treatment for CHS which can offer benefits over haloperidol.

Methods

We present three cases of patients who suffered from CHS and were admitted to emergency department. All patients were treated with olanzapine after conventional anti-hemetic treatment failure. One patient was also unsuccessfully treated with haloperidol.

Results

All three patients showed a good response to olanzapine treatment. Different presentations were effective: velotab and intramuscular. Their nausea, vomits and agitation were ameliorated. They could be discharge after maintained remission of symptoms.

Conclusions

Olanzapine should be considered as an adequate treatment for CHS. Its suitable receptorial profile, its availability in different routes of administration and its side effects profile could offer some benefits over haloperidol.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
e-Poster Walk: Consultation liaison psychiatry and psychosomatics - Part 2
Copyright
Copyright © European Psychiatric Association 2017
Submit a response

Comments

No Comments have been published for this article.
You have Access
1
Cited by

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Cannabinoid hyperemesis syndrome, a treatment discussion
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Cannabinoid hyperemesis syndrome, a treatment discussion
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Cannabinoid hyperemesis syndrome, a treatment discussion
Available formats
×
×

Reply to: Submit a response

Please enter your response.

Your details

Please enter a valid email address.

Conflicting interests

Do you have any conflicting interests? *