Hostname: page-component-7c8c6479df-ws8qp Total loading time: 0 Render date: 2024-03-29T15:04:15.470Z Has data issue: false hasContentIssue false

Anxiety and depression in haemodialysis patients in relation to dialysis adequacy and nutritional status

Published online by Cambridge University Press:  23 March 2020

L. Cui Xi*
Affiliation:
Changi general hospital, psychiatry, Singapore, Singapore
G. Michael
Affiliation:
Ng Teng Fong general hospital, dietetics & nutrition, Singapore, Singapore
Z. Chen
Affiliation:
National university of Singapore, public health, Singapore, Singapore
N.H.M. Anuar
Affiliation:
Ng Teng Fong general hospital, nursing, Singapore, Singapore
K.H.M. Yong
Affiliation:
Ng Teng Fong general hospital, psychiatry, Singapore, Singapore
R. Tagore
Affiliation:
Ng Teng Fong general hospital, renal medicine, Singapore, Singapore
*
*Corresponding author.

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.
Introduction

Anxiety and depression are distinct clinical entities associated with mortality in haemodialysis (HD) patients.

Aims

This study aims to identify the prevalence of anxiety and depression in HD patients and uncover the association of anxiety and depression in relation to the dialysis adequacy and nutritional status.

Objective

This would help reinforce early detection and treatment to improve quality of life and patient's outcome in HD treatment.

Method

Forty HD patients were assessed for anxiety and depression with the Generalised Anxiety Disorder Assessment (GAD-7 and Patient Health Questionaire [PHQ-9]). The scores of GAD-7 and PHQ-9 were correlated with the demographic, clinical and laboratory variables and nutritional status assessed by a dietician through the Subjective Global Assessment (SGA).

Results

Out of the 40 HD patients, 7 (17.5%) were anxious and 15 (37.5%) were depressed. Patients were more anxious and less depressed with better nutrition. They were less anxious and depressed with increasing albumin levels, Charlston comorbidity index based on combined condition and age-related score and Kt/V. The univariate logistic regression analysis showed only a significant inverse correlation between depression and albumin level (P = 0.041, OR = 0.88 [95% CI = 0.78 to 0.99]) and Kt/V (P = 0.054, OR = 0.03 [95% CI = 0.01 to 1.07]).

Conclusion

Depression is more prevalent than anxiety in HD patients. The risk of depression also increases with poorer dialysis adequacy and nutritional status. Thus, by improving dialysis adequacy and nutritional status, we can reduce the incidence of depression. However, a significant correlation cannot be drawn for anxiety.

Disclosure of interest

The authors have not supplied their declaration of competing interest.

Type
EV412
Copyright
Copyright © European Psychiatric Association 2016
Submit a response

Comments

No Comments have been published for this article.