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Antidepressants effect on sexual dysfunction in men with PTSD

Published online by Cambridge University Press:  13 August 2021

R. Maalej ,
G. Hamdi ,
D. Felfel ,
H. Ben Ammar ,
Y. El Kissi ,
A. Maamri  and
H. Zalila
R. Maalej
Affiliation:
Psychiatry Department, Razi, manouba, Tunisia
G. Hamdi
Affiliation:
Psychiatry Department, Razi, manouba, Tunisia Psychiatry, Tunisian Society of Clinical Sexology, TUNIS, Tunisia
D. Felfel*
Affiliation:
Psychiatry Department, Razi, manouba, Tunisia
H. Ben Ammar
Affiliation:
Psychiatry Department, Razi, manouba, Tunisia
Y. El Kissi
Affiliation:
Psychiatry, Tunisian Society of Clinical Sexology, TUNIS, Tunisia
A. Maamri
Affiliation:
Psychiatry Department, Razi, manouba, Tunisia Psychiatry, Tunisian Society of Clinical Sexology, TUNIS, Tunisia
H. Zalila
Affiliation:
Psychiatry Department, Razi, manouba, Tunisia
*
*Corresponding author.

Abstract

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Introduction

Various therapeutic approaches for post-traumatic stress disorder have been the subject of numerous studies. Antidepressants are sometimes used in PTSD. They improve the symptoms of PTSD. But their effect is not clear on the sexual dysfunctions that accompany this disorder.

Objectives

The aim of this study is to display the effect of antidepressants on sexual dysfunctions in men with PTSD.

Methods

A total of 30 male patients with PTSD were included in this study. The International Erectile Function Index (IIEF15) was used to assess sexual dysfunction in participants before treatment and two months after starting antidepressant treatment.

Results

Half of the patients (50%) used sertraline, 23% paroxetine, 20% fluoxetine and 7% escitalopram.The mean IIEF-15 score was 51.16 ± 6.82 in patients with PTSD before initiation of treatment. The average scores of the areas of sexuality studied by this scale were 3.93 ± 0.52 for sexual desire; 18.80 ± 5.68 for erectile function; 8.93 ± 8.97 for orgasmic function; 5.13 ± 1.10 for satisfaction with intercourse and 4.13 ± 1.16 for overall satisfaction. After 2 months of use of the antidepressant treatment, there was a statistically significant improvement in sexual functions: significant increase in the total score of the IIEF15 (p <0.001), and in the mean scores of the areas of sexuality.

Conclusions

Antidepressant treatment could, by improving post-traumatic symptoms, improve sexual dysfunction.

Keywords

AntidepressantSexual Dysfunctionptsd
Type
Abstract
Information
European Psychiatry , Volume 64 , Special Issue S1: Abstracts of the 29th European Congress of Psychiatry , April 2021 , pp. S553
Creative Commons
Creative Common License - CCCreative Common License - BY
This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of the European Psychiatric Association
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