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Affective symptomatology in schizophrenia: a risk factor for tardive dyskinesia?

Published online by Cambridge University Press:  16 April 2020

T.G. Schulze ,
D.J. Müller ,
H. Krauss ,
K. Marwinski ,
A.-O. Maroldt ,
A. Novo y Fernández ,
R. Fimmers ,
T. Held ,
W. Maier  and
M.M. Nöthen
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T.G. Schulze*
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
D.J. Müller
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
H. Krauss
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
K. Marwinski
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
A.-O. Maroldt
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
A. Novo y Fernández
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
R. Fimmers
Affiliation:
Institute for Medical Biometry, Informatics and Epidemiology, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
T. Held
Affiliation:
Mental State Hospital Rheinische Kliniken, Kaiser-Karl-Ring 5, D-53111Bonn, Germany
W. Maier
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
M.M. Nöthen
Affiliation:
4 Institute of Human Genetics, University of Bonn, Wilhelmstr. 31, D-53111Bonn, Germany
M. Rietschel
Affiliation:
Department of Psychiatry, University of Bonn, Sigmund-Freud-Str. 25, D-53105Bonn, Germany
*
*Correspondence and reprints: Thomas G. Schulze, MD, Department of Psychiatry, University of Chicago, Jules F. Knapp Research Center, 924 East 57th Street, Room R004, Chicago, IL 60637, USA. E-mail address: schulze@uchicago.edu (T.G. Schulze).
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Abstract

Affective symptomatology has repeatedly been suggested to confer susceptibility to tardive dyskinesia (TD). In our sample of 174 schizophrenic patients a history of depressive symptoms was not associated with the occurrence of TD, whereas manic symptomatology was significantly associated with the absence of TD. Thus, our data suggest that affective symptomatology cannot unambiguously be considered to predispose to TD.

Type
Short communication
Information
European Psychiatry , Volume 16 , Issue 1 , February 2001 , pp. 71 - 74
Copyright
Copyright © Éditions scientifiques et médicales Elsevier SAS.

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