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877 – Structural Neuroimaging Studies In Bulimia Nervosa: a Review

Published online by Cambridge University Press:  15 April 2020

L. Castro ,
E. Conceição ,
A.R. Vaz ,
E. Osório ,
I. Brandão ,
A.J. Bastos-Leite  and
P.P. Machado
L. Castro
Affiliation:
Psychiatry, Hospital Magalhães Lemos, Porto School of Psychology, University of Minho, Braga
E. Conceição
Affiliation:
School of Psychology, University of Minho, Braga
A.R. Vaz
Affiliation:
School of Psychology, University of Minho, Braga
E. Osório
Affiliation:
Department of Psychiatry, Hospital de São João Department of Psychiatry and Mental Health
I. Brandão
Affiliation:
Department of Psychiatry, Hospital de São João Department of Psychiatry and Mental Health
A.J. Bastos-Leite
Affiliation:
Department of Medical Imaging, Faculty of Medicine, University of Porto, Porto, Portugal
P.P. Machado
Affiliation:
School of Psychology, University of Minho, Braga

Abstract

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Introduction

The understanding of neurobiology of eating disorders has received a remarkable contribution from neuroimaging research.

Objective

To review the literature on structural neuroimaging in bulimia nervosa.

Aim

To discuss recent contributions of structural neuroimaging to the understanding of bulimia nervosa.

Methods

MEDLINE and PubMed databases were searched for peer-reviewed studies, published between 2000 and 2012, by using combinations of the Medline Subject Heading terms structural neuroimaging and bulimia nervosa. A selection of relevant articles to the aim of this review was carried out.

Results

Relatively few articles on structural neuroimaging were found in bulimia nervosa, and the studies showed conflicting results. Some studies reported evidence of brain volume loss in patients with bulimia nervosa, possibly related to associated chronic dietary restriction. Other studies have found increased grey matter volumes in frontal and ventral striatal areas. Finally, further studies did not find any structural abnormality at all in patients with bulimia nervosa, compared to healthy control subjects.

Conclusions

The scarce literature available on structural neuroimaging in bulimia nervosa provides conflicting results. Further studies are, therefore, warranted.

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E332
Copyright
Copyright © European Psychiatric Association 2013
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