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2201 – The Diagnosis Of Neurological Conditions Using Electrovestibulography (evestg)

Published online by Cambridge University Press:  15 April 2020

B.J. Lithgow
Affiliation:
Monash Alfred Psychiatry Research Centre, Monash University, Prahran, VIC, Australia Riverview Health Center, University of Manitoba, Winnipeg, MB, Canada Diagnostic and Neurosignal Processing Research Lab, Monash University, Clayton, VIC, Australia
Z.M. Moussavi
Affiliation:
Elec. & Comp. Engineering, University of Manitoba, Winnipeg, MB, Canada Dept. of Psychiatry, University of Manitoba, Winnipeg, MB, Canada

Abstract

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Introduction

Dizziness is a defining condition of many pathologies within DSM4. There are many emotional and behavioural impacts on the balance system. EVestG is a purported test of the balance system that has been applied to the detection of schizophrenia. However, there is a need to show whether the EVestG recordings indeed contain vestibular signals.

Objective

To investigate a clear vestibular response in EVestG recordings by analysing the signals in response to whole body passive tilts.

Methods

EVestG signals were recorded in the ear canals of 5 healthy controls (50-69yrs) and 3 unmedicated Schizophrenics (29-53yrs) in response to whole body tilts. The signals were bandpass filtered (700-4000Hz) to remove muscle interference. The Root Mean Square (RMS) of the filtered signals was measured across 0.5 sec running windows (one sample at a time) and compared between the background and tilting responses.

Results

A typical example of the RMS signal for control subjects is shown in Fig 1. During the movement phase t=20-23 and 40-43 sec wherein the vestibular is active the RMS signal showed a marked increase for all signals of all subjects. The typical Schizophrenic response had the peaks seen at t=20-23 skewed to the left.

Fig. 1

[figure 1]

Conclusions

EVestG signals do show a vestibular component. When validated with larger sample size may be assistive in neurological disorder diagnosis.

Type
Abstract
Copyright
Copyright © European Psychiatric Association 2012
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