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1359 – The Role Of Molecular Genetic Polymorphism Drd4, Dat In The Formation Of Personal Anxiety In An Open Population Men 25-64 Years In Siberia

Published online by Cambridge University Press:  15 April 2020

V. Gafarov ,
E. Gromova ,
I. Gagulin ,
A. Gafarova ,
V. Maximov  and
M. Voevoda
V. Gafarov
Affiliation:
Institute of Internal Medicine SB RAMS, Novosibirsk, Russia Collaborative Laboratory of Epidemiology of Cardiovascular Disease SB RAMS, Novosibirsk, Russia
E. Gromova
Affiliation:
Institute of Internal Medicine SB RAMS, Novosibirsk, Russia Collaborative Laboratory of Epidemiology of Cardiovascular Disease SB RAMS, Novosibirsk, Russia
I. Gagulin
Affiliation:
Institute of Internal Medicine SB RAMS, Novosibirsk, Russia Collaborative Laboratory of Epidemiology of Cardiovascular Disease SB RAMS, Novosibirsk, Russia
A. Gafarova
Affiliation:
Institute of Internal Medicine SB RAMS, Novosibirsk, Russia Collaborative Laboratory of Epidemiology of Cardiovascular Disease SB RAMS, Novosibirsk, Russia
V. Maximov
Affiliation:
Institute of Internal Medicine SB RAMS, Novosibirsk, Russia
M. Voevoda
Affiliation:
Institute of Internal Medicine SB RAMS, Novosibirsk, Russia

Abstract

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As part of WHO «MONICA» in 1994, surveyed a random representative sample of men aged 25-64 years, (n = 657). To assess the level of personal anxiety test was used Spielberger. Studied the association of gene DRD4, DAT with personal anxiety. Men in the open population of Novosibirsk, a high level of personal anxiety - 50.9%. With a high level of anxiety was significantly associated genotype 4 / 6 of the DRD4 gene and genotype 9 / 9 gene DAT.

Conclusion

In the open population of men aged 25-64 in Novosibirsk personal anxiety significantly associated with specific polymorphisms of genes DRD4, DAT.

Grant ? 11-16-54001 a/T

Type
Abstract
Information
European Psychiatry , Volume 28 , Issue S1: Abstracts of the 21th European Congress of Psychiatry , 2013 , 28-E692
Copyright
Copyright © European Psychiatric Association 2013
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