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Income, cumulative risk, and longitudinal profiles of hypothalamic–pituitary–adrenal axis activity in preschool-age children

Published online by Cambridge University Press:  04 June 2015

Maureen Zalewski*
Affiliation:
University of Oregon
Liliana J. Lengua
Affiliation:
University of Washington
Stephanie F. Thompson
Affiliation:
University of Washington
Cara J. Kiff
Affiliation:
UCLA Nathanson Family Resilience Center
*
Address correspondence and reprint requests to: Maureen Zalewski, Department of Psychology, 325 Straub Hall, 1451 Onyx Street, University of Oregon, Eugene, OR 97403; E-mail: Zalewski@uoregon.edu.

Abstract

Environmental risk predicts disrupted basal cortisol levels in preschool children. However, little is known about the stability or variability of diurnal cortisol morning levels or slope patterns over time in young children. This study used latent profile analysis to identify patterns of the hypothalamic–pituitary–adrenal axis activity during the preschool period. Using a community sample (N = 306), this study measured income, cumulative risk, and children's diurnal cortisol (morning level and slope) four times across 2.5 years, starting when children were 36 months old. Latent profile analysis profiles indicated that there were predominantly stable patterns of diurnal cortisol level and slope over time and that these patterns were predicted by income and cumulative risk. In addition, there were curvilinear relations of income and cumulative risk to profiles of low morning cortisol level and flattened diurnal slope across time, suggesting that both lower and higher levels of income and cumulative risk were associated with a stress-sensitive physiological system. Overall, this study provides initial evidence for the role of environmental risk in predicting lower, flattened basal cortisol patterns that remain stable over time.

Type
Regular Articles
Copyright
Copyright © Cambridge University Press 2015 

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