Hostname: page-component-76fb5796d-vvkck Total loading time: 0 Render date: 2024-04-27T05:12:33.186Z Has data issue: false hasContentIssue false

A Recipe for ALS

Published online by Cambridge University Press:  02 December 2014

Christen Shoesmith*
Affiliation:
London, Ontario
Rights & Permissions [Opens in a new window]

Abstract

Image of the first page of this content. For PDF version, please use the ‘Save PDF’ preceeding this image.'
Type
Editorial
Copyright
Copyright © The Canadian Journal of Neurological 2008

References

1. Valdmanis, PN, Rouleau, GA. Genetics of familial amyotrophic lateral sclerosis. Neurology. 2008; 70:14452.CrossRefGoogle ScholarPubMed
2. Ly, PT, Singh, S, Shaw, CA. Novel environmental toxins: steryl glycosides as a potential etiological factor for age-related neurodegenerative diseases. J Neurosci Res. 2007; 85:2317.CrossRefGoogle ScholarPubMed
3. van Es, MA, van Vught, PW, Blauw, HM, Franke, L, Saris, CG, Andersen, PM, et al. ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study. Lancet Neurol. 2007; 6:86977.CrossRefGoogle ScholarPubMed
4. van Es, MA, van Vught, PW, Blauw, HM, Franke, L, Saris, CG, Van den, BL, et al. Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis. Nat Genet. 2008; 40:2931.CrossRefGoogle ScholarPubMed
5. McCormick, AL, Brown, RH Jr., Cudkowicz, ME, Al-Chalabi, A, Garson, JA. Quantification of reverse transcriptase in ALS and elimination of a novel retroviral candidate. Neurology. 2008; 70:27883.CrossRefGoogle ScholarPubMed
6. Kieran, D, Kalmar, B, Dick, JR, Riddoch-Contreras, J, Burnstock, G, Greensmith, L. Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice. Nat Med. 2004; 10:4025.CrossRefGoogle ScholarPubMed
7. Neumann, M, Sampathu, DM, Kwong, LK, Truax, AC, Micsenyi, MC, Chou, TT, et al. Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science. 2006; 314:1303.CrossRefGoogle ScholarPubMed
8. Fornai, F, Longone, P, Cafaro, L, Kastsiuchenka, O, Ferrucci, M, Manca, ML, et al. Lithium delays progression of amyotrophic lateral sclerosis. Proc Natl Acad Sci USA. 2008; 105:20527.CrossRefGoogle ScholarPubMed
9. Li, B, Liu, X-Y, Li, Z, Bu, H, Sun, M-M, Guo, Y-S, et al. Effect of ALS IgG on motor neurons in organotypic spinal cord cultures. Can J Neurol Sci. 2008; 35:2205.CrossRefGoogle ScholarPubMed
10. Pagani, MR, Reisin, RC, Uchitel, OD. Calcium signaling pathways mediating synaptic potentiation triggered by amyotrophic lateral sclerosis IgG in motor nerve terminals. J Neurosci. 2006; 26: 266172.CrossRefGoogle ScholarPubMed
11. Julien, JP. ALS: astrocytes move in as deadly neighbors. Nat Neurosci. 2007; 10:5357.CrossRefGoogle ScholarPubMed
12. Rakhit, R, Robertson, J, Vande, VC, Horne, P, Ruth, DM, Griffin, J, et al. An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS. Nat Med. 2007; 13:7549.CrossRefGoogle ScholarPubMed
13. Kabashi, E, Valdmanis, PN, Dion, P, Rouleau, GA. Oxidized/ misfolded superoxide dismutase-1: the cause of all amyotrophic lateral sclerosis? Ann Neurol. 2007; 62:5539.CrossRefGoogle ScholarPubMed