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Progress in Clinical Neurosciences: Parkinson's Disease with Dementia and Dementia with Lewy Bodies

Published online by Cambridge University Press:  02 December 2014

Richard Camicioli  and
Nancy Fisher
Richard Camicioli
Affiliation:
Department of Medicine, Division of Neurology, University of Alberta, Edmonton, Alberta, Canada
Nancy Fisher
Affiliation:
Neuropsychology Program, Department of Neurosciences, University of Alberta Hospital, Neuromodulation Program, Capital Health Authority, Edmonton, Alberta, Canada
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Abstract

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Dementia occurs in up to 30% of people with Parkinson's disease and is a major cause of disability. Pathologically, Parkinson's dementia, where dementia follows the onset of parkinsonism by at least one year, overlaps with dementia with Lewy bodies. We review the functional impact, definitions, neuropsychology, epidemiology and pathophysiology of Parkinson's dementia, dementia with Lewy bodies and their overlap. Associated psychiatric and imaging findings are also considered. Lastly, current and emerging approaches to assessment and treatment in patients with these Lewy body associated dementias are presented.

Type
Review Article
Information
Canadian Journal of Neurological Sciences , Volume 31 , Issue 1 , February 2004 , pp. 7 - 21
Copyright
Copyright © The Canadian Journal of Neurological 2004

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