Hostname: page-component-848d4c4894-m9kch Total loading time: 0 Render date: 2024-05-04T05:41:07.634Z Has data issue: false hasContentIssue false
  • English
  • Français

Patterns of Memory Performance in the Neurologically Impaired Aged

Published online by Cambridge University Press:  18 September 2015

Francisco I. Perez ,
Joe R.A. Gay ,
Ronald L. Taylor  and
Victor M. Rivera
Francisco I. Perez*
Affiliation:
Departments of Neurology and Psychiatry, Baylor College of Medicine and The Baylor-Methodist Center for Cerebrovascular Research, Houston, Texas, U.S.A
Joe R.A. Gay
Affiliation:
Departments of Neurology and Psychiatry, Baylor College of Medicine and The Baylor-Methodist Center for Cerebrovascular Research, Houston, Texas, U.S.A
Ronald L. Taylor
Affiliation:
Departments of Neurology and Psychiatry, Baylor College of Medicine and The Baylor-Methodist Center for Cerebrovascular Research, Houston, Texas, U.S.A
Victor M. Rivera
Affiliation:
Departments of Neurology and Psychiatry, Baylor College of Medicine and The Baylor-Methodist Center for Cerebrovascular Research, Houston, Texas, U.S.A
*
Department of Neurology, Baylor College of Medicine, Houston, Texas 77025 U.S.A.
Rights & Permissions [Opens in a new window]

Summary:

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The specific behavioral manifestation associated with the different disorders producing the syndrome of dementia have remained poorly investigated. We examined the memory performance of three distinct groups of patients with dementia secondary to Alzheimer's disease (AD) multiple-infarctions (MID) and vertebrobasilar insufficiency (VBI) on the ten subtests of the Wechsler Memory Scale (WMS). Statistical methods of analysis were used to maximize the differences between the groups. Univariate statistical procedures revealed that the AD group performed significantly and consistently lower than the two cerebrovascular groups. There were no significant differences between the two cerebrovascular disease groups, even though the MID group tended to perform consistently more poorly than the VBI group. For heuristic and conceptual purposes as well as to determine which combination of the ten WMS variables produced the “best” statistical model differentiating the groups the data was analyzed by multivariate techniques. A discriminate function analysis obtained a 100% valid positive hit rate in discriminating among the three groups. One hundred percent diagnostic accuracy was also obtained in discriminating between MID and AD as well as AD and VBI. The two cerebrovascular groups tended to overlap in their probability distributions with an 81% hit rate. Different predicitive statistical models were identified to differentiate the various diagnostic groups. It was possible to discriminate the three diagnostic groups by different patterns of memory performance.

Type
Research Article
Information
Canadian Journal of Neurological Sciences , Volume 2 , Issue 4 , November 1975 , pp. 347 - 355
Copyright
Copyright © Canadian Neurological Sciences Federation 1975

References

REFERENCES

Cohn, J. (1959). The factorial structure of the WISC at ages 7–6, 10–6, 13–6. Journal of Consulting Psychology, 23, 285–299.CrossRefGoogle Scholar
Cooley, W.W. and Lohnes, P.R. (1971). Multivariate Data Analysis. New York: John Wiley & Sons, Inc.Google Scholar
DeJong, R.N. (1973). The neurologic aspects of dementia. Transactions of the American Neurology Association, 98, 109–113.Google ScholarPubMed
Hachinski, V.C.Lassen, N.A. and Marshall, J. (1974). Multi-infarct dementia — a cause of mental deterioration in the elderly. Lancet, 2, 207–209.CrossRefGoogle ScholarPubMed
Heilman, K.M. and Wilder, B.J. (1971). Evaluation and treatment of chronic simple dementias. Modern Treatment, 8, 219–230.Google ScholarPubMed
Inglis, J. (1966). The Scientific Study of Abnormal Behavior. Chicago: Aldine.Google Scholar
Inglis, J. (1970). Memory disorders. In Costello, C.G. (Ed). Symptoms of Psychopathology: A Handbook, New York; John Wiley.Google Scholar
Kannel, W., Blaisdell, B.Gifford, F.W., Hass, R., Mcdowell, W., Meyer, J.S., MilllKan, C.H., Rentz, L.E. and Seltser, R. (1971). Risk factors in stroke due to cerebral infarction. Stroke, 2, 423–428.CrossRefGoogle Scholar
Karp, H. (1974). Dementias in adults. In Baker, A.B. and Baker, L.H. (Eds) Clinical Neurology, Vol. 2, Chapter 27, Hagerstown, Maryland. Harper and Row Publishers.Google Scholar
Mathew, N.T. and Meyer, J.S. (1974). Pathogenesis and natural history of transient global amnesia. Stroke, 5, 303–311.CrossRefGoogle ScholarPubMed
Matthew, N.T.Hartman, A. and Ott, E.O. (1975). Abnormal CSF — blood flow dynamics in normal pressure hydrocephalus. Archives of Neurology.In Press.CrossRefGoogle Scholar
Miller, E. (1971). On the nature of the memory disorder in presenile dementia. Neuropsychologia, 9, 75–81.CrossRefGoogle ScholarPubMed
Miller, E. (1972). Efficiency of coding and the short-term memory defect in pre-senile dementia. Neuropsychologia, 10, 133–136.CrossRefGoogle Scholar
Miller, E. (1973). Short and long-term memory in patients with pre-senile dementia (Alzheimer’s Disease).. Psychological Medicine, 3, 221–224.CrossRefGoogle Scholar
Miller, E. (1974). Psychomotor performance in pre-senile dementia. Psychological Medicine, 4, 65–68.CrossRefGoogle Scholar
Pearce, J.M.S. and Miller, E. (1973). Clinical Aspects of Dementia, London. Balliere Tindall.Google Scholar
Perez, F.I., Rivera, V.M.Meyer, J.S., Gay, J.R.A., Taylor, R.L. and Mathew, N.T. (1975). Analysis of intellectual and cognitive performance in patients with multi-infarct dementia, vertebrobasilar insufficiency with dementia and Alzheimer’s Disease. Journal of Neurology, Neurosurgery and Psychiatry, 38. 533–540.CrossRefGoogle ScholarPubMed
Rivera, V.M. and Meyer, J.S.Dementia and cerebrovascular disease. In Meyer, J.S. (Ed) Modern Concepts of Cerebrovascular Disease. In Meyer, J.S. (Ed) Modern Concepts of Cerebrovascular Disease. New York. Medcom, Inc.In Preparation.Google Scholar
Ward, J. and Jennings, E. (1973). Introduction to Linear Models. Englewood Cliff, New Jersey: Prentice Hall.Google Scholar
Wechsler, D.A. (1945). A standardized memory scale for clinical use. Journal of Psychology, 19, 87–95.CrossRefGoogle Scholar