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The Murine Ependymoblastoma: Growth Pattern and Survival in C57B1/6J Mice

Published online by Cambridge University Press:  18 September 2015

Paul J. Muller ,
Kyu H. Shin  and
Doo H. Shin
Paul J. Muller
Affiliation:
Tom Baker Cancer Centre and the Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta
Kyu H. Shin*
Affiliation:
Tom Baker Cancer Centre and the Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta
Doo H. Shin
Affiliation:
Tom Baker Cancer Centre and the Department of Clinical Neurosciences, University of Calgary, Calgary, Alberta
*
1331-29 Street N.W., Calgary, Alberta, Canada, T2N 4N2.
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The murine ependymoblastoma is a transplantable tumor of cerebral origin. The growth pattern and survival times of the murine ependymoblastoma implanted peripherally and intracranially in non nude C57B1/6J mice have been found to be predictable and consistent when examined by means of Tumor Cell Dose Assessment (end point solution), Tumor Growth and Survival Assessment. The results suggest that a greater tumor cell dose is required to generate peripheral tumor take than brain tumor take. This difference may result from a greater immunologic response to tumor implanted peripherally than into the immunologically privileged brain.

Type
Original Articles
Information
Canadian Journal of Neurological Sciences , Volume 10 , Issue 2 , May 1983 , pp. 105 - 109
Copyright
Copyright © Canadian Neurological Sciences Federation 1983

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