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Intrauterine Hydrocephalus and Ventriculomegaly: Associated Abnomalies and Fetal Outcome

Published online by Cambridge University Press:  18 September 2015

D. D. Cochrane ,
S. T. Myles ,
C. Nimrod ,
D. K. Still ,
R. G. Sugarman  and
B. K. Wittmann
D. D. Cochrane*
Affiliation:
Department of Clinical Neurosciences
S. T. Myles
Affiliation:
Department of Clinical Neurosciences
C. Nimrod
Affiliation:
Departments of Obstetrics and Gynecology, University of Calgary
D. K. Still
Affiliation:
University of Alberta
R. G. Sugarman
Affiliation:
University of Saskatchewan
B. K. Wittmann
Affiliation:
University of British Columbia, Faculties of Medicine, Calgary, Edmonton, Saskatoon, Vancouver
*
Suite 207, 803-1 Avenue N.E., Calgary, Alberta, Canada T2E 7C5
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Abstract:

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Advances in fetal diagnostic techniques have opened many areas to prenatal anatomical scrutiny. Intrauterine hydrocephalus and ventriculomegaly are conditions which are readily diagnosed. Fetal intervention has been undertaken in humans in order to minimize the craniofacial disfigurement and to maximize the growth potential of the brain. To justify such an approach, the significance of all anomalies should be recognized prior to treatment. The authors have reviewed 41 cases of hydrocephalus diagnosed in utero in order to define associated anomalies and patient outcome.

75% of our personal series and 72% of the reviewed literature cases had other anomalies of the central nervous system. Other system malformations, some of which proved fatal, were seen commonly. Prenatal diagnostic techniques did not always reveal these additional problems.

The outcome of these pregnancies is not good. Approximately one third of these fetuses have survived to be treated postnatally and to be followed up clinically. Only 7.5% of this series were felt to have attained normal developmental milestones. The remainder of the survivors have various focal and/or global cerebral deficits.

Type
Articles
Information
Canadian Journal of Neurological Sciences , Volume 12 , Issue 1 , February 1985 , pp. 51 - 59
Copyright
Copyright © Canadian Neurological Sciences Federation 1985

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