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Intraparenchymal Epithelial (Enterogenous) Cyst of the Medulla Oblongata

Published online by Cambridge University Press:  18 September 2015

Boleslaw Lach*
Affiliation:
Division of Anatomical Pathology (Neuropathology), Ottawa Civic Hospital and University of Ottawa
Neville Russell
Affiliation:
Division of Neurosurgery, Ottawa Civic Hospital and University of Ottawa
David Atack
Affiliation:
Division of Neurology, Ottawa Civic Hospital and University of Ottawa
Brien Benoit
Affiliation:
Division of Neurosurgery, Ottawa Civic Hospital and University of Ottawa
*
Laboratory Medicine, Ottawa Civic Hospital, 1053 Carling Ave., Ottawa, Ontario, Canada K1Y 4E9
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Abstract:

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intraparenchymal solitary cyst of the medulla oblongata was diagnosed on MRI examination in a 66-year-old woman with a nine year history of progressive brainstem dysfunction and three negative CT scan examinations. Craniotomy and drainage of the cyst to the IVth ventricle led to remarkable clinical recovery. Biopsy of the wall of the cyst revealed an epithelial lining with tonofilaments, desmosomes and surface coating on ultrastructural examination. Immunohistochemistry demonstrated positive reactions of epithelium for keratins, cytokeratins, epithelial membrane antigen and Ulex Europeus lectin, indicating endodermal origin of the cyst.

Type
Original Articles
Copyright
Copyright © Canadian Neurological Sciences Federation 1989

References

REFERENCES

1.Friede, RL.Developmental neuropathology, Springer-Verlag, New York-Wien, 1975; 196202 and 266–271.CrossRefGoogle Scholar
2.Friede, RL, Yasargil, M.Supratentorial epithelial (ependymal) cysts: Review, case reports, and fine structure. J Neurol Neurosurg Psych 1977; 40: 127137.CrossRefGoogle ScholarPubMed
3.Jakubiak, P, Dunsmore, RH, Beckett, RS.Supratentorial brain cysts. J Neurosurg 1968; 28: 129136.Google Scholar
4.Leech, RW, Olafson, RA.Epithelial cysts of neuroaxis. Arch Pathol Lab Med 1977; 101: 196202.Google Scholar
5.Rubinstein, LJ.Tumors of the central nervous system. Atlas of tumor pathology. Second series. Fasc 6, Armed Forces Inst. of Path. Washington, DC; 1972; 285292.Google Scholar
6.Bouch, DC.Mitchell, I, Maloney, AFJ.Ependymal lined paraventricular cerebral cysts: A report of three cases. J Neurol Neurosurg Psych 1973; 36: 611617.CrossRefGoogle ScholarPubMed
7.Rilliet, B, Berney, J.Benign ependymal cyst of the pons. Childs Brain 1981; 8: 18.Google ScholarPubMed
8.Sharma, BS, Banerjee, AK, Khosla, VK, et al. Congenital intramedullary spinal ependymal cyst. Surg Neurol 1987; 27: 476480.CrossRefGoogle ScholarPubMed
9.Ho, KL, Chasen, JL.A glioependymal cyst of the cerebello-pontine angle. Immunohistochemical and ultrastructural studies. Acta Neuropath (Berl) 1987; 74: 382388.CrossRefGoogle Scholar
10.Andrews, BT, Halks-Miller, M, Berger, MS, et al. Neuroepithelial cyst of the posterior fossa: Pathogenesis and report of two cases. Neurosurg 1984; 15: 9195.CrossRefGoogle ScholarPubMed
11.Hasagawa, H, Ushio, Y, Oku , Y, et al. Neuroepithelial cyst of the cerebellar vermis. Surg Neurol 1976; 6: 181184.Google Scholar
12.Pokrupa, R, Montpetit, V, Richard, M.Fine structure and postulated origin of intracerebral neuroepithelial cyst. Neuropath Exp Neurol 1983; 42: 356(A).CrossRefGoogle Scholar
13.Afshar, F, Scholtz, CL.Enterogenous cyst of the fourth ventricle. J Neurosurg 1981; 54: 836838.CrossRefGoogle ScholarPubMed
14.Giombini, S, Lodrini, S, Migiliavacca, F.Intracranial enterogenous cyst. Surg Neurol 1981; 6: 181, 16: 271–273.Google Scholar
15.Walls, TJ, Purohit, DP, Aji, WS, et al. Multiple intracranial enterogenous cysts. J Neurol Neurosurg Psych 1986; 49: 438441.CrossRefGoogle ScholarPubMed
16.Matsushima, T, Fukui, M, Egami, H.Epithelial cells in a so-called intraspinal neuroenteric cyst: A light and electromicroscopic study. Surg Neurol 1985; 24: 656660.CrossRefGoogle Scholar
17.Yamashita, J, Maloney, AFJ, Harris, P.Intradural spinal bronchogenic cyst. Case report. J Neurosurg 1973; 39: 2401245.CrossRefGoogle Scholar
18.Schelper, RL, Kagan-Hallett, KS, Huntington, HW.Brainstem sub-arachnoid respiratory epithelial cysts. Report of two cases and review of literature. Hum Pathol 1986; 17: 417422.CrossRefGoogle Scholar
19.Dorsay, JF, Tabrisky, J.Intraspinal and mediastial foregut cyst compressing spinal cord: Report of a case. J Neurosurg 1966; 24: 562567.CrossRefGoogle Scholar
20.Inoue, T, Kuromatsu, C, Iwata, Y, et al. Symptomatic choroidal epithelial cyst in the fourth ventricle. Surg Neurol 1985; 24: 5762.CrossRefGoogle ScholarPubMed
21.Inoue, T, Masushima, T, Fukuyi, M, et al. Choroidal epithelial cysts of the cerebral hemisphere. An immunohistochemical study. Surg Neurol 1987; 28: 119122.CrossRefGoogle ScholarPubMed
22.Koto, A, Horoupian, DS, Shulman, K.Choroidal epithelial cyst. Case report. J Neurosurg 1977; 47: 955960.CrossRefGoogle ScholarPubMed
23.Netsky, MG, Shuangshoti, GS.The choroid plexus in Health and Disease. Wright and Sons, Bristol 1975; 199248.Google Scholar
24.Hirano, A, Ghatak, NR, Wisoff, HS, et al. An epithelial cyst of the spinal cord. An electron microscopy study. Acta Neuropath (Berl) 1971; 214223.CrossRefGoogle Scholar
25.Ghatak, NR, Hirano, A, Kassoff, SS, et al. Fine structure of an intracerebral epithelial cyst. J Neurosurg 1974; 41: 7582.CrossRefGoogle ScholarPubMed
26.MacGregor, BJL, Gawler, J, South, JR.Intracranial epithelial cysts. Report of two cases. J Neurosurg 1976; 44: 109115.CrossRefGoogle ScholarPubMed
27.Hirai, O, Kawamura, J, Fukumitsu, T.Prepontine epithelium-lined cyst. Neurosurg 1981; 55: 312317.CrossRefGoogle ScholarPubMed
28.Gherardi, R, Lacombe, MJ, Poirier, J, et al. Asymptomatic encephalic intraparenchymatous neuroepithelial cysts. Acta Neuropath (Berl) 1984; 63: 264268.CrossRefGoogle ScholarPubMed
29.Mortara, RH, Marksbery, WR, Brooks, WH.Pontine cyst presenting as trigeminal pain. Case report. J Neurosurg 1974; 41: 636639.CrossRefGoogle ScholarPubMed
30.Scott, M, Silverstein, A.Intrapontine cyst verified by surgical drainage into the fourth ventricle. J Neurosurg 1960; 17: 520528.CrossRefGoogle Scholar
31.Inoue, T, Matsushima, T, Fukui, M, et al. Immunohistochemical study of Intracranial Cysts. Neurosurg 1988; 23: 576581.CrossRefGoogle ScholarPubMed
32.Izukawa, D, Lach, B.Immunocytochemical analysis of intermediate filaments in human ependymal tumors. Can J Neurol Sci 1988; 15: 114118.CrossRefGoogle ScholarPubMed
33.Hirano, A, Ghatak, NR.The fine structure of colloid cysts of the third ventricle. J Neuropathol Exper Neurol 1974; 33: 333341.CrossRefGoogle ScholarPubMed
34.Lach, B, Scheithauer, , Wick, MR.Histogenesis of the colloid cyst. Ultrastructural and immunohistochemical studies. Presented at the IVth Congress of Neuropathology, Stockholm, Sept. 1986.Google Scholar
35.Miettinen, M, Clark, R, Virtanen, I.Intermediate filament proteins in choroid plexus and ependyma and their tumors. Am J Path 1986; 123: 231240.Google ScholarPubMed
36.Sloan, JP, Ormerod, MG.Distribution of epithelial membrane antigen in normal and neoplastic tissues and its value in diagnostic tumor pathology. Cancer 1981; 47: 17861795.3.0.CO;2-8>CrossRefGoogle Scholar
37.Cooper, D, Schermer, A, Sun, TT.Classification of human epithelia and their neoplasms using monoclonal antibodies to keratins: Strategies, applications and limitations. Lab Invest 1985; 52: 143256.Google ScholarPubMed
38.Coffin, ChM, Wick, MR, Braun, JT, et al. Choroid plexus neoplasms, clinicopathologic and immunohistochemical studies. Am J Surg Pathol 1986; 10: 394404.CrossRefGoogle ScholarPubMed
39.Kasper, M, Karsten, U, Stosiek, P.Detection of cytokeratin(s) in epithelium of human plexus choroideus by monoclonal antibodies. Acta Histochem 1986; 8: 101103.CrossRefGoogle Scholar
40.Damianov, I.Biology of disease. Lectin cytochemistry and histo-chemistry. Lab Invest 1987; 57: 520.Google Scholar
41.Geleff, S, Bock, P, Stockinger, L.Lectin-binding affinities of the epithelium in the respiratory tract. A light microscopical study of ciliated epithelium in rat, guinea pig and hamster. Acta Histochem 1986; 78: 8395.CrossRefGoogle ScholarPubMed
42.Perentes, E, Rubinstein, LJ.Recent applications of immuno-peroxi-dase histochemistry in human neuro-oncology. Arch Path Lab Med 3 1987; 796812.Google Scholar
43.Pinel, JF, Larmande, P, Guegan, Y, Iba-Zizen, MT.Down-beat nystagnus: Case report with magnetic resonance imaging and surgical treatment. Neurosurgery 1987; 21: 736739.CrossRefGoogle Scholar
44.McKissock, W.The surgical treatment of colloid cyst of the third ventricle. A report based upon twenty-one personal cases. Brain 1951: 74: 19.CrossRefGoogle ScholarPubMed