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Hypertension and Stroke: 2005 Canadian Hypertension Educational Program Recommendations

Published online by Cambridge University Press:  02 December 2014

J.M. Boulanger*
Affiliation:
Canadian Hypertension Educational Program, Foothills Hospital, Calgary, Alberta, Canada
Michael D. Hill
Affiliation:
Canadian Hypertension Educational Program, Foothills Hospital, Calgary, Alberta, Canada
*
c/o Michael Hill, Foothills Hospital, Room 1242A, 1403 - 29th Street NW, Calgary, Alberta, Canada T2N 2T9
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Abstract:

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Background:

Hypertension is the most important modifiable cause of stroke. The Canadian Hypertension Educational Program, representing Canada's experts in the field of hypertension, publishes annual evidence-based recommendations on the diagnosis and treatment of hypertension.

Methods:

We present the 2005 Canadian Hypertension Educational Program guidelines regarding the management of hypertension in patients with stroke.

Results:

The diagnosis of hypertension should be expedited and can be made as early as the second visit in patients with stroke. Unless contraindicated, a combination of angiotensin-converting-enzyme (ACE) inhibitors and diuretics is the preferred therapy in these patients. A target blood pressure below 140/90mmHg for non-diabetic patients, below 130mmHg/80mmHg for diabetic patients and below 125mmHg/75mmHg for those with renal disease and proteinuria (³ 1 gram per day) should be reached. Lifestyle interventions may be as effective as medication and should be used in conjunction with medical management. Waist circumference should be less than 102cm for men and 88cm for women. There remains uncertainty about the management of high blood pressure in the context of acute stroke.

Conclusions:

A combination of ACE-inhibitors and diuretics is recommended in hypertensive stroke patients. Blood pressure should be maintained below 140/90 mmHg.

Résumé:

RÉSUMÉ:Contexte:

L’hypertension est la cause modifiable la plus importante de l’accident vasculaire cérébral (AVC). L’hypertension est la cause principale de l’AVC. Le Groupe de travail du Programme éducatif canadien sur l’hypertension (PÉCH) est formé d’experts canadiens dans le domaine de l’hypertension. Il publie à chaque année des recommandations fondées sur des données probantes sur le diagnostic et le traitement de l’hypertension.

Méthodes:

Nous présentons les recommandations 2005 du PÉCH sur la prise en charge de l’hypertension chez les patients ayant subi un AVC.

Résultats:

Le diagnostic de l’hypertension doit être accéléré chez les patients ayant subi un AVC. Il peut même être fait à la deuxième visite d’évaluation de la pression artérielle chez ces patients. Le traitement de choix chez ces patients est l’association d’un inhibiteur de l’enzyme de conversion de l’angiotensine (ECA) et d’un diurétique, à moins qu’il n’existe des contre-indications à ce traitement. Les valeurs cibles de pression artérielle sont de moins de 140/90 mmHg chez les patients qui ne sont pas diabétiques, de moins de 130/80 mmHg chez les diabétiques et de moins de 125/75 mmHg chez les patients atteints de néphropathie ayant une protéinurie (> 1 gr par jour). Les interventions axées sur le mode de vie peuvent être aussi efficaces que la médication et devraient être utilisées en association avec la médication. Le tour de taille devrait être de moins de 102 cm chez l’homme et de moins de 88 cm chez la femme. La prise en charge d’une pression artérielle élevée dans le contexte d’un AVC aigu demeure controversée.

Conclusions:

L’association d’un ECA et d’un diurétique est recommandée chez les patients ayant subi un AVC et la pression artérielle devrait être maintenue sous 140/90 mmHg.

Type
Review Article
Copyright
Copyright © The Canadian Journal of Neurological 2005

References

1. AmericanHeartAssociationstatistics. Available at: www.americanheart.org.Google Scholar
2. Mohr, JP, Choi, DW, Grotta, JC, et al. Stroke: Pathophysiology,diagnosis, and management. Churchill Livingstone 2004. 4th ed. page 15.Google Scholar
3. Langille, DB, Joffres, MR, MacPherson, KM, et al. Prevalence of riskfactors for cardiovascular disease in Canadians 55 to 74 years of age: results from the Canadian Heart Health Surveys, 1986-1992. CMAJ 1999;161(8 Suppl):S3-9.Google Scholar
4. Yiannakoulias, N, Svenson, LW, Hill, MD, et al. Incidentcerebrovascular disease in rural and urban Alberta.. Cerebrovasc Dis 2004; 17:7278.Google Scholar
5. Bobrie, G, Chatellier, G, Genes, N et al. Cardiovascular prognosis of “masked hypertension” detected by blood pressure self-measurement in elderly treated hypertensive patients. JAMA 2004;291:13421349.CrossRefGoogle ScholarPubMed
6. Asayama, K, Ohkubo, T, Kikuya, M, et al. Prediction of stroke byself-measurement of blood pressure at home versus casual screening blood pressure measurement in relation to the Joint National Committee 7 Classification. The Ohsama study. Stroke 2004;35:23562361.Google Scholar
7. Ohkubo, T, Imai, Y, Tsuji, I, et al. Home blood pressure measurementhas a stronger predictive power for mortality than does screening blood pressure measurement: a population-based observation in Ohasama, Japan. J Hypertens 1998;16:971975.Google Scholar
8. Clement, DL, De Buyzere, ML, De Bacquer Da, , et al. For the Officeversus Ambulatory (OvA) Pressure Study Investigators. Prognostic value of ambulatory blood pressure recordings in patients with treated hypertension. N Engl J Med 2003;348:24072415.Google Scholar
9. Staessen, JA, Thijs, L, Fagard, R, et al. Predicting cardiovascular riskusing conventional vs ambulatory blood pressure in older patients with systolic hypertension. JAMA 1999;282:539546.Google Scholar
10. Thijs, L, Staessen, JA, Celis, H, et al. Reference values for self-recorded blood pressure: a meta-analysis of summary data. Arch Intern Med 1998;158:481488.Google Scholar
11. Julius, S, Kjeldsen, SE, Weber, M, et al. Outcomes in hypertensivepatients at high cardiovascular risk treated with regimens based on valsartan or amlodipine: the VALUE randomised trial. Lancet 2004;363:20222031.Google Scholar
12. Poole-Wilson, PA, Lubsen, J, Kirwan, BA, et al for the A CoronaryDisease Trial Investigating Outcome with Nifedipine gastrointestinal therapeutic system (ACTION trial) investigators. Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTIONtrial):A randomisedcontrolled trial. Lancet 2004;364:849857.Google Scholar
13. Pepine, CJ, Handberg, EM, Cooper-Dehoff, RM, et al. For theINVEST Investigators. A calcium antagonist vs a non-calcium antagonist hypertension treatment strategy for patients with coronary artery disease. The International Verapamil-Trandolapril Study (INVEST): A randomized controlled trial. JAMA 2003;290:28052816.Google Scholar
14. Pfeffer, MA, McMurray, JJV, Velazquez, EJ, et al. For the VALIANTInvestigators. Valsartan, captopril or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both: the Valiant Trial. N Engl J Med 2003;349:18931906.Google Scholar
15. Blood Pressure Lowering treatment Trialists collaboration. Effectsof different blood-pressure lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials. Lancet 2003;362:15271535.CrossRefGoogle Scholar
16. Angeli, F, Verdecchia, P, Reboldi, GP, et al. Calcium channel blockadeto prevent stroke in hypertension: a meta-analysis of 13 studies with 103 793 subjects. Am J Hypertens 2004;17:817822.Google Scholar
17. Hansson, L, Lindholm, LH, Niskanen, L, et al. Effect of angiotensin-converting enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the captopril prevention project (CAPP) randomised trial. Lancet 1999;353:611616.Google Scholar
18. The ALLHAT Officers and coordinators for the ALLHATcollaborative research group. Major outcomes in high-risk hypertensive patients randomised to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic. The Antihypertensive and Lipid-Lowering treatment to prevent Heart Attack Trial (ALLHAT). JAMA 2002;288:29812997.Google Scholar
19. Shortt, J. Obesity: a public health dilemma. AORN J 2004;80:10691078.CrossRefGoogle ScholarPubMed
20. Writing Group of the PREMIER Collaborative Research Group. JAMA 2003;289:20832093.Google Scholar
21. Ishikawa-takata, K, Ohta, T, Tanaka, H. How much exercise isrequired to reduce blood pressure in essential hypertension: a dose-response study. Am J Hypertens 2003;16:629633.Google Scholar
22. Appel, LJ. Moore, TJ. Obarzanek, E. A clinical trial of the effects ofdietary patterns on blood pressure. N Engl J Med 1997; 336(16):11171124.Google Scholar
23. Sacks, FM. Svetkey, LP. Vollmer, WM. Effects on blood pressure ofreduced dietary sodium and the dietary approaches to stop hypertension (DASH) DIET. N Engl J Med 2001;344:310.Google Scholar
24. Janssen, I, Katzmarzyk, PT, Ross, R. Body mass index, waistcircumference, and health risk: evidence in support of current National Institutes of Health guidelines. Arch Intern Med 2002;162:20742079.Google Scholar
25. Progress collaborative Group. Randomised trial of a perindopril-based blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. Lancet 2001;358:10331041. Google Scholar
26. Collins, R, Armitage, J, Parish, S, Sleight, P, Peto, R; Heart ProtectionStudy Collaborative Group. Effects of cholesterol-lowering with simvastatin on stroke and other major vascular events in 20536 people with cerebrovascular disease or other high-risk conditions. Lancet 2004; 363:757767.Google Scholar
27. International society of hypertension Writing Group. InternationalSociety of hypertension (ISH): Statement on the Management of Blood Pressure in Acute Stroke. J Hypertens 2003;21:665672.Google Scholar
28. Leonardi-Bee, J, Bath, PM, Phillips, SJ, Sandercock, PA; FirstCollaborative Group. Blood pressure and clinical outcomes in theInternational Stroke Trial. Stroke 2002; 33: 13151320.Google Scholar
29. Schrader, J, Luders, S, Kulschewski, A. The ACCESS Study:evaluation of acute candesartan cilexetil therapy in strokesurvivors. Stroke 2003;34:1699-1703.Google Scholar
30. Adams, HP, Chair, J, Adams, RJ, et al. Guidelines for the earlymanagement of patients with ischemic stroke. Stroke 2003;34:10561083.Google Scholar
31. Broderick, JP, Adams, HP, Barsan, W, et al. Guidelines for theManagement of spontaneous intracranial hemorrhage. Stroke 1999;30:905915.Google Scholar
32. Anonymous. The National Institutes of Neurological Disorders andStroke rt-PA Stroke Study Group. Tissue plasminogen activator for acute ischemic stroke. The National Institute of Neurological Disorders and Stroke rt-PA Stroke Study Group. N Engl J Med 1995;333:15811587.Google Scholar
33. Ahmed, N, Nasman, P, Wahlgren, G. Effect of intravenous nimodipineon blood pressure and outcome after acute stroke. Stroke 2002;31:12501255.Google Scholar
34. Rosenbaum, D, Zabramski, J, Frey, J, et al. Early treatment ofischemic stroke with a calcium antagonist. Stroke 1991;22:437441.CrossRefGoogle Scholar