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Hair trace elements in Friedreich's disease

Published online by Cambridge University Press:  18 September 2015

A. Barbeau ,
M. Roy  and
S. Paris
A. Barbeau*
Affiliation:
Department of Neurobiology, Clinical Research Institute of Montreal, Montreal.
M. Roy
Affiliation:
Department of Neurobiology, Clinical Research Institute of Montreal, Montreal.
S. Paris
Affiliation:
Department of Neurobiology, Clinical Research Institute of Montreal, Montreal.
*
Clinical Research Institute of Montreal, 110 Pine Avenue West, Montreal, Quebec, Canada, H2W 1R7
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Abstract

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Concentrations of zinc, copper, manganese, chromium, cobalt and selenium were measured in the hair obtained from subjects with Friedreich’s disease, other inherited ataxias and neurological control patients. Althought zinc and copper concentrations were significantly higher in Friedreich than in the two control groups, the mean values for all groups were well within the normal range. No major deficiency in zinc or selenium was demonstrated in Friedreich’s disease using the approach. This does not, however, indicate that there is no defect in zinc and selenium metabolism, availability or transport in this disorder.

Type
C—Biochemistry
Information
Canadian Journal of Neurological Sciences , Volume 11 , Issue S4 , November 1984 , pp. 620 - 622
Copyright
Copyright © Canadian Neurological Sciences Federation 1984

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