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The EEG in Alzheimer type Dementia: Lack of Progression with Sequential Studies

Published online by Cambridge University Press:  18 September 2015

A.D. Rae-Grant ,
W.T. Blume ,
K. Lau ,
M. Fisman ,
V. Hachinski  and
H. Merskey
A.D. Rae-Grant*
Affiliation:
Dementia Study Group, University of Western Ontario, London, Ontario
W.T. Blume
Affiliation:
Dementia Study Group, University of Western Ontario, London, Ontario
K. Lau
Affiliation:
Dementia Study Group, University of Western Ontario, London, Ontario
M. Fisman
Affiliation:
Dementia Study Group, University of Western Ontario, London, Ontario
V. Hachinski
Affiliation:
Dementia Study Group, University of Western Ontario, London, Ontario
H. Merskey
Affiliation:
Dementia Study Group, University of Western Ontario, London, Ontario
*
Department of Neurosciences, University Hospital, University of Western Ontario, London, Ontario, Canada N6A 5A5
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Abstract:

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Our findings dispel the commonly held belief that the EEG always worsens progressively in dementia of the Alzheimer's type. In a continuing cohort analytical study of dementia, 139 patients with Alzheimer's disease and 148 controls were studied for EEG abnormalities and progression. EEGs were read without knowledge of the previous EEGs or clinical condition, and classified according to the presence of diffuse delta or theta, bisynchronousspikes, projected activity, and focal activity. EEGs were significantly different in the two groups. EEG scores generally worsened over 1-4 years, but most of the subjects showed no alteration in their EEG scores. A few patients with Alzheimer's disease showed improvement of EEG findings.

Type
Clinical and Therapeutic Issues
Information
Canadian Journal of Neurological Sciences , Volume 13 , Issue S4 , November 1986 , pp. 407 - 409
Copyright
Copyright © Canadian Neurological Sciences Federation 1986

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