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Vitamin and mineral nutrition in chronic alcoholocs including patients nwith Korsakoff's psychosis

Published online by Cambridge University Press:  09 March 2007

M. S. Devgun ,
Anna Fiabane ,
C. R. Paterson ,
P. Zarembski  and
Anne Guthrie
M. S. Devgun
Affiliation:
Department of Biochemical Medicine, Ninewells Hospital and Medical School, Ninewells, Dundee DD1 9SY
Anna Fiabane
Affiliation:
Department of Biochemical Medicine, Ninewells Hospital and Medical School, Ninewells, Dundee DD1 9SY
C. R. Paterson
Affiliation:
Department of Biochemical Medicine, Ninewells Hospital and Medical School, Ninewells, Dundee DD1 9SY
P. Zarembski
Affiliation:
Department of Biochemical Medicine, Ninewells Hospital and Medical School, Ninewells, Dundee DD1 9SY
Anne Guthrie
Affiliation:
Murray Royal Hospital, Perth PH2 7BH
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Abstract

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1. A group of 129 patients with chronic alcoholism were assessed for their nutritional status with respect to certain minerals and vitamins, and compared with control subjects.

2. In all subjects the plasma values were normal for calcium, magnesium and zinc.

3. As in other studies a seasonal variation was found in the plasma levels of 25-hydroxyvitamin D in the control subjects and the alcoholic subjects; in all seasons lower levels were found in the alcoholics than in the controls, but none of the alcoholic patients had results in the range found in osteomalacia.

4. The alcoholic subjects had low levels of ascorbic acid both in the plasma and in the leucocytes.

5. Although vitamin A and β-carotene levels were within the reference range, the results in alcoholics were found to be lower than in the control subjects.

6. We suggest that subclinical vitamin deficiencies other than thiamine deficiency contribute to the cerebral impairment frequently found in alcoholism.

Type
Papers of direct relevance to Clinical and Human Nutrition
Information
British Journal of Nutrition , Volume 45 , Issue 3 , May 1981 , pp. 469 - 473
Copyright
Copyright © The Nutrition Society 1981

References

REFERENCES

Baines, M. (1978). Analyt Clin. Biochem. 15, 307.CrossRefGoogle Scholar
Bhat, P. V. & Rao, P. B. R. (1978). Wld Rev. Nutr. Diet. 31, 100.CrossRefGoogle Scholar
Bogdon, J. D. & Troiano, R. A. (1978). Clin. Chem. 24, 1553.CrossRefGoogle Scholar
Carlsson, C., Claeson, L. E. & Pettersson, L. (1973). Br. J. Addict. 68, 83.Google Scholar
Chan, A. W. K. (1978). Pharmacology 27, 1259.Google Scholar
Comar, C. L. & Bronner, F. (1964). Mineral metabolism – an advanced treatise. New York: Academic Press.Google Scholar
Denson, K. W. & Bowers, E. F. (1961). Clin. Sci. 21, 157.Google Scholar
Dugan, R. E., Frigerio, N. A. & Siebert, J. M. (1964). Analyt Chem. 36, 114.CrossRefGoogle Scholar
Eckardt, M. J., Parker, E. S., Noble, E. P., Feldman, D. J. & Gottschalk, L. A. (1978). Biol. Psychiatr. 13, 551.Google Scholar
Erbslon, F. & Abel, M. (1970). In Handbook of clinicalneurology, vol. 7 [Vinken, and Bruyn, , editors]. Amsterdam: North Holland Publishing Co.Google Scholar
Fennelly, J., Frank, O., Baker, H. & Leevy, C. M. (1964). Br. Med. J. 2, 1290.CrossRefGoogle Scholar
Gitelman, H. J. (1967). Analyt Biochem. 18, 520.CrossRefGoogle Scholar
Graham, J. R., Woodhouse, D. & Read, F. H. (1971). Lancet ii, 107.CrossRefGoogle Scholar
Guthrie, A. (1980). In Biological effects of alcohol, vol. 126, p. 745 [Kissin, B. and Ekgleiter, H., editors]. New York: Plenum Press.CrossRefGoogle Scholar
Guthrie, A. & Elliott, W. A. (1980). J. Stud. Alc. 41, 147.CrossRefGoogle Scholar
Guthrie, A., Presly, A., Geekie, C. & MacKenzie, C. (1980). In The Psychopharmacology of alcohol, [Sandier, M., editor]. New York: Raven Press.Google Scholar
Heaton, F. W., Pyrah, L. N., Beresford, C. C., Bryson, R. W. & Martin, D. F. (1962). Lancet ii, 802.CrossRefGoogle Scholar
Henderson, G. I., Hoyumpa, A. M. & Schenker, S. (1978). Pharmacology 27, 1677.Google Scholar
Hurst, K. O. (1964). Can. J. Biochem. 42, 287.CrossRefGoogle Scholar
Kessler, G. & Wolfman, M. (1964). Clin. Chem. 10, 686.CrossRefGoogle Scholar
Kind, P. R. N. & King, E. J. J. (1954). J. Clin. Path. 7, 322.CrossRefGoogle Scholar
Krasner, N., Dow, J., Moore, M. R. & Goldberg, A. (1974). Lancet ii, 693.CrossRefGoogle Scholar
Kuo, C. H., Hata, F., Yoshida, H., Yamatodani, A. & Wada, H. (1979). Life Sci. 24, 911.CrossRefGoogle Scholar
Lawrence, R. (1974). Ann. Clin. Biochem. 11, 234.CrossRefGoogle Scholar
Lund, H. & Sorenson, O. H. (1979). Scand. J. Clin. Lab. Invest. 39, 23.CrossRefGoogle Scholar
Lund, H., Sorensen, O. H., Hilden, M. & Lund, B. (1977). Acta Med. Scand. 202, 221.CrossRefGoogle Scholar
McCraw, A. & Sim, A. K. (1969). Clin. Chim. Acta. 25, 286.CrossRefGoogle Scholar
McLaughlin, M., Raggatt, R., Fairney, A., Brown, J., Lester, E. & Wills, R. (1974). Lancet i, 536.CrossRefGoogle Scholar
Marks, J. (1968). The vitamins in health and disease – a modern reappraisal. London: Churchill.Google Scholar
Mullier, J. P., Taverne, J. U., Brauman, J., Futeral, B., Kutnowski, M. & Verbanck, M. (1979). Ann. Endocrinol. 40, 177.Google Scholar
Neeld, I. B. & Pearson, W. N. (1963). J. Nutr. 79, 454.CrossRefGoogle Scholar
Nordin, B. E. C. (1976). Calcium, phosphate and magnesium metabolism: clinical physiology and diagnostic procedures, p. 186. Edinburgh: Churchill.Google Scholar
Olson, F., Michaels, G., Partridge, J. W., Boling, L., Margen, S. & Kinsell, L. W. (1953). Am. J. Clin. Nutr. 1, 134.CrossRefGoogle Scholar
Ornstein, P. (1977). Psychol. Rep. 40, 719.CrossRefGoogle Scholar
Parker, M. M., Humoller, F. L. & Mahler, D. J. (1967). Clin. Chem. 13, 40.CrossRefGoogle Scholar
Perkoff, G. T., Dioso, M. M., Bleisch, V. & Klinkerfuss, G. (1967). Ann. Intern. Med. 67, 481.CrossRefGoogle Scholar
Pittman, J. G. & Decker, J. W. (1971). Neurology 21, 293.CrossRefGoogle Scholar
Poskitt, E. M. E., Cole, T. J. & Lawson, D. E. M. (1979). Br. Med. J. 2, 221.CrossRefGoogle Scholar
Posner, D. B., Russell, R. M., Absood, S., Comer, T. B., Davis, C., Martin, L., Williams, J. B., Noms, A. H. & Merchant, C. (1978). Gastroenterology 74, 866.CrossRefGoogle Scholar
Prasad, A. S. (1966). Zinc metabolism. Illinois: Charles C. Thomas.Google Scholar
Preece, M. A., O'Riordan, J. L. H., Lawson, D. E. M. & Kodicek, E. (1974). Clin. Chim. Acta. 54, 235.CrossRefGoogle Scholar
Tarter, R. E. (1971). A neuropsychological examination of cognitive and perceptual capacities in chronic alcoholics. PhD dissertation. University of Oklahoma.Google Scholar
Taylor, A. N. (1977). J. Nutr. 107, 480.CrossRefGoogle Scholar
Vallance, S. (1979). Br. J. Nurr. 41, 409.CrossRefGoogle Scholar
Varley, H. (1969). Practical clinical biochemistry, 4th ed. London: Heinemann.Google Scholar
Victor, M., Adams, R. D. & Collins, G. H. (1971). In The Wernicke-Korsakoff syndrome. Oxford: Blackwell.Google ScholarPubMed
Walravens, P. A. (1980). Clin. Chem. 26, 185.CrossRefGoogle Scholar
Wiggart, A., Mizukawa, A., Kuwabara, T. & Chader, G. J. (1978). J. Neurochem. 30, 653.CrossRefGoogle Scholar
Willis, L. B. (1961). Analyt Chem. 33, 556.CrossRefGoogle Scholar