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Vitamin A status and the metabolism of cholesterol in the rat

Published online by Cambridge University Press:  09 March 2007

M. R. Lakshmanan ,
W. E. J. Phillips  and
R. L. Brien
M. R. Lakshmanan
Affiliation:
Research Laboratories, Food and Drug Directorate, Department of National Health and Welfare, Ottawa, Canada
W. E. J. Phillips
Affiliation:
Research Laboratories, Food and Drug Directorate, Department of National Health and Welfare, Ottawa, Canada
R. L. Brien
Affiliation:
Research Laboratories, Food and Drug Directorate, Department of National Health and Welfare, Ottawa, Canada
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Abstract

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1. The interrelationship between cholesterol and vitamin A metabolism has been studied in rats.

2. The effect of cholesterol feeding in increasing the liver storage of cholesterol w-as enhanced during vitamin A deficiency.

3. This effect was due to an increased rate of absorption of cholesterol and not due to a decreased turnover rate.

4. Feeding of high levels of vitamin A markedly depressed the cholesterol absorption; however, its turnover was unaffected.

Type
Research Article
Information
British Journal of Nutrition , Volume 23 , Issue 1 , March 1969 , pp. 25 - 30
Copyright
Copyright © The Nutrition Society 1969

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