Hostname: page-component-76fb5796d-5g6vh Total loading time: 0 Render date: 2024-04-26T11:07:13.525Z Has data issue: false hasContentIssue false

The measurement of food iron absorption in man

Published online by Cambridge University Press:  08 December 2008

L. Hallberg
Affiliation:
Department of Medicine II, Sahlgrenska sjukhuset, University of Göteborg, S-413 45, Göteborg, Sweden
E. Björn-Rasmussen
Affiliation:
Department of Medicine II, Sahlgrenska sjukhuset, University of Göteborg, S-413 45, Göteborg, Sweden
L. Rossander
Affiliation:
Department of Medicine II, Sahlgrenska sjukhuset, University of Göteborg, S-413 45, Göteborg, Sweden
R. Suwanik
Affiliation:
Department of Radiology, Siriraj Hospital, Madihol University, Bangkok 7, Thailand
Rights & Permissions [Opens in a new window]

Abstract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. The present study was considered as a first step to develop a method to measure food iron absorption from realistic common meals prepared and consumed by the subjects themselves in their own homes. The absorption of Fe from the meals was measured by means of the extrinsic-tag method modified to allow for a free choice of food items.

2. The mean Fe intake was 2.79 mg and the mean Fe absorption approximately 0.30 mg. The Fe status of the subjects corresponded to 31.5% absorption from a reference dose solution containing 3 mg elemental Fe as ferrous ascorbate. The variation in food Fe absorption obtained in this field study was found to be of the same magnitude as that obtained in studies performed under more controlled conditions as in the laboratory.

3. The conclusion was drawn that the proposed method could be used in realistic field studies aimed at, for example, explaining or preventing a high prevalence of deficiency. A sufficiently long run-in period and a careful instruction of the subjects was considered essential for the design of future field studies.

Type
Papers of direct relevance to Clinical and Human Nutrition
Copyright
Copyright © The Nutrition Society 1979

References

Björn-Rasmussen, E., Hallberg, L., Isaksson, B. & Arvidsson, B. (1974). J. clin. Invest. 53, 247.CrossRefGoogle Scholar
Björn-Rasmussen, E., Hallberg, L., Magnusson, B., Rossander, L., Svanberg, B. & Arvidsson, B. (1976). Am. J. clin. Nutr. 29, 772.CrossRefGoogle Scholar
Cook, J. D., Layrisse, M., Martinez-Torres, C., Walker, R., Monsen, E. & Finch, C. A. (1972). J. clin. Invest. 51, 805.CrossRefGoogle Scholar
Hallberg, L. & Björn-Rasmussen, E. (1972). Scand. J. Haemat. 9, 193.Google Scholar
Layrisse, M. & Martinez-Torres, C. (1972). Am. J. clin. Nutr. 25, 401.Google Scholar