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Hypocholesterolaemic effects of milk-kefir and soyamilk-kefir in cholesterol-fed hamsters

Published online by Cambridge University Press:  08 March 2007

Je-Ruei Liu*
Department of Biotechnology, National Formosa University, Yunlin, Taiwan
Sheng-Yao Wang
Department of Animal ScienceNational Taiwan University, Taipei, Taiwan
Ming-Ju Chen
Department of Animal ScienceNational Taiwan University, Taipei, Taiwan
Hsiao-Ling Chen
Department of Molecular Biotechnology, Da-Yeh University, Changhua, Taiwan
Pei-Ying Yueh
Council of Agriculture Executive Yuan, TaipeiTaiwan
Chin-Wen Lin
Department of Animal ScienceNational Taiwan University, Taipei, Taiwan
*Corresponding author: Dr J.-R. Liu, fax +886 5 6315502, email
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This study aimed to evaluate the hypocholesterolaemic property of milk-kefir and soyamilk-kefir. Male hamsters were fed on a cholesterol-free or cholesterol-enriched diet containing 10% skimmed milk, milk-kefir, soyamilk or soyamilk-kefir for a period of 8 weeks. The soyamilk, milk-kefir and soyamilk-kefir diets all tended towards a lowering of serum triacylglycerol and total cholesterol concentrations, and a reduction of cholesterol accumulation in the liver, the decrease in serum cholesterol concentration being mainly in the non-HDL fraction. The soyamilk-kefir diet led to a significant increase in the faecal excretion of neutral sterols and bile acids compared with the other two diets. The soyamilk-kefir diet also elicited a significant decrease in the serum ratio of non-HDL-cholesterol to HDL-cholesterol, compared with the control, than was the case for the other diets. These findings demonstrate that soyamilk-kefir may be considered to be among the more promising food components in terms of preventing CVD through its hypocholesterolaemic action.

Research Article
Copyright © The Nutrition Society 2006


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