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Genomics and proteomics: importance for the future of nutrition research

Published online by Cambridge University Press:  09 March 2007

H. Daniel
H. Daniel*
Affiliation:
Molecular Nutrition Unit, Department of Food and Nutrition, Technical University of Munich, Hochfeldweg 2, D-85350 Freising-Weihenstephan, Germany
*
*Corresponding author: Prof. Dr H. Daniel, tel +49 8161 713 400, fax +49 8161 713 999, email daniel@weihenstephan.de
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Abstract

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A huge number of genes within the human genome code for proteins that mediate and/or control nutritional processes. Although a large body of information on the number of genes, on chromosomal localisation, gene structure and function has been gathered, we are far from understanding the orchestrated way of how they make metabolism. Nevertheless, based on the genetic information emerging on a daily basis, we are offered fantastic new tools that allow us new insights into the molecular basis of human metabolism under normal as well as pathophysiological conditions. Recent technological advancements have made it possible to analyse simultaneously large sets of mRNA and/or proteins expressed in a biological sample or to define genetic heterogeneity that may be important for the individual response of an organism to changes in its nutritional environment. Applications of the new techniques of genome and proteome analysis are central for the development of nutritional sciences in the next decade and its integration into the rapidly developing era of functional genomics.

Keywords

GenomeProteomeNutrition research
Type
Research Article
Information
British Journal of Nutrition , Volume 87 , Issue S2 , May 2002 , pp. S305 - S311
Copyright
Copyright © The Nutrition Society 2002

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