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The effect of a low-protein diet and a cold environment on calorie intake and body composition in the rat

Published online by Cambridge University Press:  09 March 2007

P. Schmida  and
Elise M. Widdowson
P. Schmida
Affiliation:
Medical Research Council Department of Experimental Medicine, University of Cambridge
Elise M. Widdowson
Affiliation:
Medical Research Council Department of Experimental Medicine, University of Cambridge
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Abstract

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1. Rats 10 weeks old were fed for 9 weeks either on a stock diet containing 17% protein, or on a low-protein diet prepared from the stock diet with added glucose, minerals and vitamins. Half the animals on each diet were kept at room temperature (21°) and half in a cold environment (5°).

2. The calorie intake of the animals kept at 5° on both diets was 60–70% higher than that of the corresponding group at 21°. The animals on the stock diet and kept at 5° gained weight but not so much as those on the same diet at 21°. The animals kept on the low-protein diet at 21° lost weight, while those on the same diet at 5° lost only a little weight initially and none thereafter.

3. On both types of diet the liver, kidneys and gastro-intestinal tract weighed more per 100 g body-weight in animals kept in the colder of the two environments; the small intestine was conspicuous in this respect.

4. The weight of the fur was greater, and the weight of the skin less per 100 g body-weight at 5° than at 21°.

5. The animals on the stock diet at 21° had most fat in their bodies, both in absolute terms and per 100 g body-weight. There were no significant differences between the other three groups.

6. The skin of the animals kept at 5° had a significantly higher collagen to N ratio than the skin of those having the same diet at 21°.

Type
Research Article
Information
British Journal of Nutrition , Volume 21 , Issue 2 , May 1967 , pp. 457 - 465
Copyright
Copyright © The Nutrition Society 1967

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