Skip to main content Accessibility help
×
Hostname: page-component-76fb5796d-qxdb6 Total loading time: 0 Render date: 2024-04-27T17:44:44.940Z Has data issue: false hasContentIssue false

Chapter 7 - HIV, AIDS, and Tuberculosis

Published online by Cambridge University Press:  20 July 2023

Mark Curato
Affiliation:
Weill Cornell Medicine, New York
Kaushal Shah
Affiliation:
Weill Cornell Medicine, New York
Christopher Reisig
Affiliation:
Weill Cornell Medicine, New York
Get access

Summary

In the Emergency Department, patients present with diverse infectious diseases. Some diseases require a keen eye from the clinician to diagnose and prevent transmission and progression. HIV and TB are two conditions that are easily overlooked in the ED, yet are the two deadliest infectious diseases in the world. The HIV/AIDS epidemic has been a challenge to the United States health system since the 1980s and continues to represent major health and economic burden. TB cases in the US had been down trending in the 1950s, but since 1985 cases began to rise in urban areas where large communities of immigrants are present. The HIV and TB pandemics are largely intertwined because TB is a major cause of death in HIV patients. Most cases in the US are concentrated in urban areas of low income. Individuals of color, those experiencing homelessness, engaging in high-risk sexual behavior, and those with substance use disorder are the most likely to be affected. Advances in therapeutics as well as the development of screening modalities have made significant progress. The Emergency Department is the major point of contact for diagnosis and linkage to long-term care.

Type
Chapter
Information
Publisher: Cambridge University Press
Print publication year: 2023

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

References

Denning, P, DiNenno, E. Communities in crisis: is there a generalized HIV epidemic in impoverished urban areas of the United States? Presented at XVIII International AIDS Conference (AIDS 2010), Vienna, Austria. 2010.Google Scholar
Nunn, A, Yolken, A, Cutler, B, Trooskin, S, Wilson, P, Little, S, Mayer, K. Geography should not be destiny: focusing HIV/AIDS implementation research and programs on microepidemics in US neighborhoods. Am J Public Health. 2014;104:775780. doi.org/10.2105/AJPH.2013.301864CrossRefGoogle Scholar
Hall, HI, Espinoza, L, Benbow, N, Hu, YW, for the Urban Areas HIV Surveillance Workgroup. Epidemiology of HIV infection in large urban areas in the United States. PLoS One. 2010;5(9):e12756. https://doi.org/10.1371/journal.pone.0012756Google Scholar
Department of Health and Human Services. National Strategic Plan. A Roadmap to End the Epidemic for the United States 2021–2025. Department of Health and Human Services, 2021.Google Scholar
Leider, J, Fettig, J, Calderon, Y. Engaging HIV-positive individuals in specialized care from an urban emergency department. AIDS Patient Care STDS. 2011;25(2):8993. doi:10.1089/apc.2010.0205CrossRefGoogle ScholarPubMed
Reliasmedia.com. Tuberculosis: A Primer for the Emergency Physician [online]. 2022. Available at: www.reliasmedia.com/articles/100438-tuberculosis-a-primer-for-the-emergency-physician (accessed January 28, 2022).Google Scholar
Skaathun, B, Pho, MT, Pollack, HA, Friedman, SR, McNulty, MC, Friedman, EE, Schmitt, J, Pitrak, D, Schneider, JA. Comparison of effectiveness and cost for different HIV screening strategies implemented at large urban medical centre in the United States. J Int AIDS Soc. 2020;23(10):e25554. doi:10.1002/jia2.25554. PMID: 33119195; PMCID: PMC7594703.Google Scholar
Shapiro, NI, Karras, DJ, Leech, SH, Heilpern, KL. Absolute lymphocyte count as a predictor of CD4 count. Ann Emerg Med. 1998;32(3 Pt 1):323328. doi:10.1016/s0196-0644(98)70008-3. PMID: 9737494.Google Scholar
Hussein, M, Diez Roux, AV, Field, RI. Neighborhood socioeconomic status and primary health care: usual points of access and temporal trends in a major US urban area. J Urban Health. 2016;93(6):10271045. doi:10.1007/s11524-016-0085-2. Erratum in: J Urban Health. 2016;93(6):1046. PMID: 27718048; PMCID: PMC5126022.Google Scholar
Daniel, TM. The history of tuberculosis. Respir Med. 2006;100(11):18621870. https://doi.org/10.1016/j.rmed.2006.08.006.Google Scholar
Maison, DP. Tuberculosis pathophysiology and anti-VEGF intervention. J Clin Tuberc Other Mycobact Dis. 2022;27:100300. https://doi.org/10.1016/j.jctube.2022.100300Google Scholar
Center of Disease Control and Prevention. Transmission and pathogenesis of tuberculosis. Retrieved January 1, 2022, from www.cdc.gov/tb/education/corecurr/pdf/chapter2.pdfGoogle Scholar
Sia, IG, Wieland, ML. Current concepts in the management of tuberculosis. Mayo Clin Proc. 2011:86(4):348361.CrossRefGoogle ScholarPubMed
Adigun, R, Singh, R. Tuberculosis. StatPearls. 2022. Available from www.ncbi.nlm.nih.gov/books/NBK441916/Google Scholar
Oren, E, Winston, CA, Pratt, R, Robison, VA, Narita, M. Epidemiology of urban tuberculosis in the United States, 2000–2007. Am J Public Health. 2011;101(7):12561263. doi:10.2105/AJPH.2010.300030CrossRefGoogle ScholarPubMed
Centers for Disease Control and Prevention. Tuberculosis. 2022. Retrieved from www.cdc.gov/tb/default.htmGoogle Scholar
Mutembo, S, Mutanga, JN, Musokotwane, K, Kanene, C, Dobbin, K, Yao, X, Li, C, Marconi, VC, Whalen, CC. Urban–rural disparities in treatment outcomes among recurrent TB cases in Southern Province, Zambia. BMC Infect Dis. 2019;19(1):1087. doi:10.1186/s12879-019-4709-5Google Scholar

Further Reading

Trepka, MJ, Fennie, KP, Sheehan, DM, Lutfi, K, Maddox, L, Lieb, S. Late HIV diagnosis: differences by rural/urban residence, Florida, 2007–2011. AIDS Patient Care STDS. 2014;28(4):188197. doi:10.1089/apc.2013.0362CrossRefGoogle ScholarPubMed
Sarno, EL, Bettin, E, Jozsa, K, Newcomb, ME. Sexual health of rural and urban young male couples in the United States: differences in HIV testing, pre‐exposure prophylaxis use, and condom use. AIDS Behav. 2021;25(1):191202. doi.org/10.1007/s10461-020-02961-8.Google Scholar
El-Sadr, WM, Mayer, KH, Hodder, SL. AIDS in America – Forgotten but not gone. New Engl J Med. 2010;362(11):967970. doi:10.1056/NEJMp1000069Google Scholar
Spaulding, AC, MacGowan, RJ, Copeland, B, Shrestha, RK, Bowden, CJ, Kim, MJ, Margolis, A, Mustaafaa, G, Reid, LC, Heilpern, KL, Shah, BB. Costs of rapid HIV screening in an urban emergency department and a nearby county jail in the southeastern United States. PLoS One. 2015;10(6):e0128408. https://doi.org/10.1371/journal.pone.0128408CrossRefGoogle Scholar
Reif, S, Golin, CE, Smith, SR. Barriers to accessing HIV/AIDS care in North Carolina: rural and urban differences. AIDS Care. 2005;17(5):558565. doi:10.1080/09540120412331319750Google Scholar
Haukoos, JS, Mehta, SD, Harvey, L, Calderon, Y, Rothman, RE. Research priorities for human immunodeficiency virus and sexually transmitted infections surveillance, screening, and intervention in emergency departments: consensus-based recommendations. Acad Emerg Med. 2009;16(11):10961102. doi:10.1111/j.1553-2712.2009.00546.x. PMID: 20053228; PMCID: PMC4733316.Google Scholar
Blanchard, E, Klibanov, OM, Axelrod, P, Palermo, B, Samuel, R. Virologic success in an urban HIV clinic: outcome at 12 months in patients who were HAART naïve. HIV Clin Trials. 2008;9(3):186191. doi:10.1310/hct0903-186. PMID: 18547905.Google Scholar
Peto, HM, Pratt, RH, Harrington, TA, LoBue, PA, Armstrong, LR. Epidemiology of extrapulmonary tuberculosis in the United States, 1993–2006. Clin Infect Dis. 2009;49(9):13501357. doi:10.1086/605559. PMID: 19793000.Google Scholar
Wang, E, Sohoni, A. Tuberculosis: a primer for the emergency physician. Emerg Med Rep. 2006. www.reliasmedia.com/articles/100438-tuberculosis-a-primer-for-the-emergency-physician (accessed January 29, 2022).Google Scholar

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×