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13 - Male Infertility and Assisted Reproduction

Published online by Cambridge University Press:  25 May 2017

Christopher J. De Jonge
Affiliation:
University of Minnesota
Christopher L. R. Barratt
Affiliation:
University of Dundee
Ryuzo Yanagimachi
Affiliation:
University of Hawaii, Manoa
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Summary

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Chapter
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The Sperm Cell
Production, Maturation, Fertilization, Regeneration
, pp. 193 - 207
Publisher: Cambridge University Press
Print publication year: 2017

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References

Palermo, GD, Kocent, J, Monahan, D, Neri, QV, Rosenwaks, Z. Treatment of male infertility. Methods Mol Biol 2014; 1,154: 385405.Google Scholar
Schmidt, L. Social and psychological consequences of infertility and assisted reproduction – What are the research priorities? Hum Fertil (Camb) 2009; 12(1): 1420.CrossRefGoogle ScholarPubMed
Odisho, AY, Nangia, AK, Katz, PP, Smith, JF. Temporal and geospatial trends in male factor infertility with assisted reproductive technology in the United States from 1999–2010. Fertil Steril 2014; 102(2): 469–75.CrossRefGoogle ScholarPubMed
Neri, QV, Hu, J, Rosenwaks, Z, Palermo, GD. Understanding the spermatozoon. Methods Mol Biol 2014; 1,154: 91119.CrossRefGoogle Scholar
Turek, PJ. Male Infertility. In Yen & Jaffe's Reproductive Endocrinology, seventh ed. Elsevier, 2013: 538–50.Google Scholar
World Health Organization. Laboratory Manual for the Examination and Processing of Human Semen, fifth ed. WHO Press, 2010: 238.Google Scholar
Guzick, DS, Overstreet, JW, Factor-Litvak, P et al. Sperm morphology, motility, and concentration in fertile and infertile men. N Engl J Med 2001; 345(19): 1,388–93.Google Scholar
Sigman, M, Baazeem, A, Zini, A. Semen analysis and sperm function assays: What do they mean? Semin Reprod Med 2009; 27(2): 115–23.Google Scholar
Funaro, M, Paduch, DA. Novel markers of male infertility. Methods Mol Biol 2014; 1,154: 233–50.CrossRefGoogle Scholar
Dohle, GR, Elzanaty, S, van Casteren, NJ. Testicular biopsy: Clinical practice and interpretation. Asian J Androl. 2012; 14(1): 8893.Google Scholar
Jha, KN, Coleman, AR, Wong, L, Salicioni, AM, Howcroft, E, Johnson, GR. Heat shock protein 90 functions to stabilize and activate the testis-specific serine/threonine kinases, a family of kinases essential for male fertility. J Biol Chem 2013; 288(23): 16,308–20.Google Scholar
Brewer, L, Corzett, M, Balhorn, R. Condensation of DNA by spermatid basic nuclear proteins. J Biol Chem 2002; 277(41): 38,895900.Google Scholar
Ward, WS. Deoxyribonucleic acid loop domain tertiary structure in mammalian spermatozoa. Biol Reprod 1993; 48(6): 1,193201.Google Scholar
Palermo, GD, Neri, QV, Cozzubbo, T, Rosenwaks, Z. Perspectives on the assessment of human sperm chromatin integrity. Fertil Steril 2014; 102(6): 1,508–17.Google Scholar
Barratt, CL, Aitken, RJ, Björndahl, L et al. Sperm DNA: Organization, protection and vulnerability: from basic science to clinical applications – A position report. Hum Reprod 2010; 25(4): 824–38.Google Scholar
Zini, A, Bielecki, R, Phang, D, Zenzes, MT. Correlations between two markers of sperm DNA integrity, DNA denaturation and DNA fragmentation, in fertile and infertile men. Fertil Steril 2001; 75(4): 674–7.Google Scholar
Kumar, K, Deka, D, Singh, A, Mitra, DK, Vanitha, BR, Dada, R. Predictive value of DNA integrity analysis in idiopathic recurrent pregnancy loss following spontaneous conception. J Assist Reprod Genet 2012; 29(9): 861–7.Google Scholar
Dugum, M, Sandlow, JI, Brannigan, RE. Sperm DNA damage evaluation techniques. J Androl 2011; 32(3): 207–9.CrossRefGoogle ScholarPubMed
Boe-Hansen, GB, Fedder, J, Ersbøll, AK, Christensen, P. The sperm chromatin structure assay as a diagnostic tool in the human fertility clinic. Hum Reprod 2006; 21(6): 1,576–82.CrossRefGoogle ScholarPubMed
Sharma, R, Masaki, J, Agarwal, A. Sperm DNA fragmentation analysis using the TUNEL assay. Methods Mol Biol 2013; 927: 121–36.CrossRefGoogle ScholarPubMed
Henkel, R, Kierspel, E, Hajimohammad, M et al. DNA fragmentation of spermatozoa and assisted reproduction technology. Reprod Biomed Online 2003; 7(4): 477–84.Google Scholar
Morris, ID, Ilott, S, Dixon, L, Brison, DR. The spectrum of DNA damage in human sperm assessed by single cell gel electrophoresis (comet assay) and its relationship to fertilization and embryo development. Hum Reprod 2002; 17(4): 990–8.Google Scholar
Schlegel, PN, Paduch, DA. Yet another test of sperm chromatin structure. Fertil Steril 2005; 84(4): 854–9.CrossRefGoogle ScholarPubMed
Hassold, T, Hunt, P. To err (meiotically) is human: The genesis of human aneuploidy. Nat Rev Genet 2001; 2(4): 280–91.CrossRefGoogle Scholar
Jodar, M, Selvaraju, S, Sendler, E et al. The presence, role and clinical use of spermatozoal RNAs. Hum Reprod Update 2013; 19(6): 604–24.Google Scholar
Krawetz, SA, Kruger, A, Lalancette, C et al. A survey of small RNAs in human sperm. Hum Reprod 2011; 26(12): 3,401–12.Google Scholar
Vogt, PH, Human, Y. Chromosome deletions in Yq11 and male fertility. Adv Exp Med Biol 1997; 424: 1730.Google Scholar
Griffin, DK, Finch, KA. The genetic and cytogenetic basis of male infertility. Hum Fertil (Camb) 2005; 8(1): 1926.CrossRefGoogle ScholarPubMed
Reik, W. Stability and flexibility of epigenetic gene regulation in mammalian development. Nature 2007; 447(7143): 425–32.Google Scholar
Reik, W, Dean, W. DNA methylation and mammalian epigenetics. Electrophoresis 2001; 22(14): 2,838–43.Google Scholar
Oakes, CC, La Salle, S, Smiraglia, DJ, Robaire, B, Trasler, JM. A unique configuration of genome-wide DNA methylation patterns in the testis. Proc Natl Acad Sci USA 2007; 104(1): 228–33.Google Scholar
Sunderam, S, Kissin, DM, Crawford, SB et al. Assisted reproductive technology surveillance – United States, 2012. MMWR Surveill Summ 2015; 64 Suppl 6: 129.Google Scholar
Cohen, J, Edwards, RG, Fehilly, CB et al. Treatment of male infertility by in vitro fertilization: Factors affecting fertilization and pregnancy. Acta Eur Fertil 1984; 15(6): 455465.Google Scholar
Palermo, GD, Cohen, J, Alikani, M, Adler, A, Rosenwaks, Z. Intracytoplasmic sperm injection: A novel treatment for all forms of male factor infertility. Fertil Steril 1995; 63(6): 1,231–40.CrossRefGoogle ScholarPubMed
Mahadevan, MM, Trounson, AO. The influence of seminal characteristics on the success rate of human in vitro fertilization. Fertil Steril 1984; 42(3): 400405.Google Scholar
Palermo, GD, Neri, QV, Schlegel, PN, Rosenwaks, Z. Intracytoplasmic sperm injection (ICSI) in extreme cases of male infertility. PLoS One 2014; 9(12): e113671.Google Scholar
Palermo, GD, Neri, QV, Rosenwaks, Z. To ICSI or not to ICSI. Semin Reprod Med 2015; 33(2): 92102.Google Scholar
Palermo, GD, Neri, QV, Takeuchi, T, Rosenwaks, Z. ICSI: Where we have been and where we are going. Semin Reprod Med 2009; 27(2): 191201.CrossRefGoogle ScholarPubMed
Kiessling, AA, Loutradis, D, McShane, PM, Jackson, KV. Fertilization in trypsin-treated oocytes. Ann NY Acad Sci 1988; 541: 614–20.Google Scholar
Gordon, JW, Talansky, BE. Assisted fertilization by zona drilling: A mouse model for correction of oligospermia. J Exp Zool 1986; 239(3): 347–54.Google Scholar
Cohen, J, Malter, H, Fehilly, C et al. Implantation of embryos after partial opening of oocyte zona pellucida to facilitate sperm penetration. Lancet 1988; 2(8,603): 162.CrossRefGoogle ScholarPubMed
Palermo, G, Joris, H, Derde, MP, Camus, M, Devroey, P, Van Steirteghem, A. Sperm characteristics and outcome of human assisted fertilization by subzonal insemination and intracytoplasmic sperm injection. Fertil Steril 1993; 59(4): 826–35.Google Scholar
Palermo, G, Joris, H, Devroey, P, Van Steirteghem, AC. Pregnancies after intracytoplasmic injection of single spermatozoon into an oocyte. Lancet 1992; 340(8,810): 17–8.Google Scholar
Lin, TP. Microinjection of mouse eggs. Science 1966; 151(3,708): 333–7.CrossRefGoogle ScholarPubMed
Lanzendorf, SE, Maloney, MK, Veeck, LL, Slusser, J, Hodgen, GD, Rosenwaks, Z. A preclinical evaluation of pronuclear formation by microinjection of human spermatozoa into human oocytes. Fertil Steril 1988; 49(5): 835–42.Google Scholar
Ishihara, O, Adamson, GD, Dyer, S et al. International committee for monitoring assisted reproductive technologies: World report on assisted reproductive technologies, 2007. Fertil Steril 2015; 103(2): 402–13.e11.Google Scholar
Boulet, SL, Mehta, A, Kissin, DM, Warner, L, Kawwass, JF, Jamieson, DJ. Trends in use of and reproductive outcomes associated with intracytoplasmic sperm injection. JAMA 2015; 313(3): 255–63.Google Scholar
Bhattacharya, S, Hamilton, MP, Shaaban, M et al. Conventional in-vitro fertilisation vs intracytoplasmic sperm injection for the treatment of non-male-factor infertility: a randomised controlled trial. Lancet 2001; 357(9,274): 2,075–9.Google Scholar
Jain, T, Gupta, RS. Trends in the use of intracytoplasmic sperm injection in the United States. N Engl J Med 2007; 357(3): 251–7.Google Scholar
Practice Committees of the American Society for Reproductive Medicine and Society for Assisted Reproductive Technology. Intracytoplasmic sperm injection (ICSI) for non-male factor infertility: A committee opinion. Fertil Steril 2012; 98(6): 1,395–9.Google Scholar
Wosnitzer, M, Goldstein, M, Hardy, MP. Review of azoospermia. Spermatogenesis 2014; 4: e28218.Google Scholar
Silber, SJ, Nagy, ZP, Liu, J, Godoy, H, Devroey, P, Van Steirteghem, AC. Conventional in-vitro fertilization versus intracytoplasmic sperm injection for patients requiring microsurgical sperm aspiration. Hum Reprod 1994; 9(9): 1,705–9.Google Scholar
Tournaye, H, Devroey, P, Liu, J, Nagy, Z, Lissens, W, Van Steirteghem, A. Microsurgical epididymal sperm aspiration and intracytoplasmic sperm injection: A new effective approach to infertility as a result of congenital bilateral absence of the vas deferens. Fertil Steril 1994; 61(6): 1,045–51.Google Scholar
Mansour, RT, Aboulghar, MA, Serour, GI, Fahmi, I, Ramzy, AM, Amin, Y. Intracytoplasmic sperm injection using microsurgically retrieved epididymal and testicular sperm. Fertil Steril 1996; 65(3): 566–72.Google Scholar
Devroey, P, Liu, J, Nagy, Z, Tournaye, H, Silber, SJ, Van Steirteghem, AC. Normal fertilization of human oocytes after testicular sperm extraction and intracytoplasmic sperm injection. Fertil Steril 1994; 62(3): 639–41.Google Scholar
Schlegel, PN, Li, PS. Microdissection TESE: sperm retrieval in non-obstructive azoospermia. Hum Reprod Update 1998; 4(4): 439.Google Scholar
Schlegel, PN. Testicular sperm extraction: Microdissection improves sperm yield with minimal tissue excision. Hum Reprod 1999; 14(1): 131–5.Google Scholar
Donoso, P, Tournaye, H, Devroey, P. Which is the best sperm retrieval technique for non-obstructive azoospermia? A systematic review. Hum Reprod Update. 2007; 13(6): 539–49.Google Scholar
Van Steirteghem, AC, Nagy, Z, Joris, H et al. High fertilization and implantation rates after intracytoplasmic sperm injection. Hum Reprod 1993; 8(7): 1,061–6.Google Scholar
De Sutter, P, Dozortsev, D, Qian, C, Dhont, M. Oocyte morphology does not correlate with fertilization rate and embryo quality after intracytoplasmic sperm injection. Hum Reprod 1996; 11(3): 595–7.Google Scholar
Moreno, C, Ruiz, A, Simón, C, Pellicer, A, Remohí, J. Intracytoplasmic sperm injection as a routine indication in low responder patients. Hum Reprod 1998; 13(8): 2,126–9.Google Scholar
Boyers, SP, Diamond, MP, Lavy, G, Russell, JB, DeCherney, AH. The effect of polyploidy on embryo cleavage after in vitro fertilization in humans. Fertil Steril 1987; 48(4): 624–7.Google Scholar
Jun, SH, O'Leary, T, Jackson, KV, Racowsky, C. Benefit of intracytoplasmic sperm injection in patients with a high incidence of triploidy in a prior in vitro fertilization cycle. Fertil Steril 2006; 86(4): 825–9.Google Scholar
Stahl, PJ, Schlegel, PN, Goldstein, M. Sperm retrieval and quality evaluation. Methods Mol Biol 2014; 1,154: 361–84.Google Scholar
Semião-Francisco, L, Braga, DP, Figueira Rde, C et al. Assisted reproductive technology outcomes in azoospermic men: 10 years of experience with surgical sperm retrieval. Aging Male 2010; 13(1): 4450.Google Scholar
Tournaye, H. Surgical sperm recovery for intracytoplasmic sperm injection: Which method is to be preferred? Hum Reprod 1999; 14 Suppl 1: 7181.Google Scholar
Donoso, P, Tournaye, H, Devroey, P. Which is the best sperm retrieval technique for non-obstructive azoospermia? A systematic review. Hum Reprod Update 2007; 13(6): 539–49.Google Scholar
Park, KS, Song, HB, Chun, SS. Late fertilization of unfertilized human oocytes in in vitro fertilization and intracytoplasmic sperm injection cycles: Conventional insemination versus ICSI. J Assist Reprod Genet 2000; 17(8): 419–24.CrossRefGoogle ScholarPubMed
Tsirigotis, M, Nicholson, N, Taranissi, M, Bennett, V, Pelekanos, M, Craft, I. Late intracytoplasmic sperm injection in unexpected failed fertilization in vitro: Diagnostic or therapeutic? Fertil Steril 1995; 63(4): 816–9.CrossRefGoogle ScholarPubMed
Lundin, K, Sjögren, A, Hamberger, L. Reinsemination of one-day-old oocytes by use of intracytoplasmic sperm injection. Fertil Steril 1996; 66(1): 118–21.Google Scholar
Morton, PC, Yoder, CS, Tucker, MJ, Wright, G, Brockman, WD, Kort, HI. Reinsemination by intracytoplasmic sperm injection of 1-day-old oocytes after complete conventional fertilization failure. Fertil Steril 1997; 68(3): 488–91.Google Scholar
Tucker, M, Elsner, C, Kort, H, Massey, J, Mitchell-Leef, D, Toledo, A. Poor implantation of cryopreserved reinsemination-fertilized human embryos. Fertil Steril 1991; 56(6): 1,111–6.Google Scholar
Plachot, M, de Grouchy, J, Junca, AM, Mandelbaum, J, Salat-Baroux, J, Cohen, J. Chromosome analysis of human oocytes and embryos: Does delayed fertilization increase chromosome imbalance? Hum Reprod 1988; 3(1): 125–7.Google Scholar
Palermo, GD, Neri, QV, Takeuchi, T, Squires, J, Moy, F, Rosenwaks, Z. Genetic and epigenetic characteristics of ICSI children. Reprod Biomed Online 2008; 17(6): 820–33.Google Scholar
Palermo, GD, Neri, QV, Rosenwaks, Z. Safety of intracytoplasmic sperm injection. Methods Mol Biol 2014; 1,154: 549–62.Google Scholar
Palermo, GD, Colombero, LT, Schattman, GL, Davis, OK, Rosenwaks, Z. Evolution of pregnancies and initial follow-up of newborns delivered after intracytoplasmic sperm injection. JAMA 1996; 276(23): 1,893–7.Google Scholar
Neri, QV, Takeuchi, T, Kang, HJ, Lin, K, Wang, A, Palermo, GD. Genetic assessment and development of children that result from assisted reproductive technology. Clin Obstet Gynecol 2006; 49(1): 134–7.Google Scholar
Bowen, JR, Gibson, FL, Leslie, GI, Saunders, DM. Medical and developmental outcome at 1 year for children conceived by intracytoplasmic sperm injection. Lancet 1998; 351(9,115): 1,529–34.CrossRefGoogle ScholarPubMed
Bonduelle, M, Joris, H, Hofmans, K, Liebaers, I, Van Steirteghem, A. Mental development of 201 ICSI children at 2 years of age. Lancet 1998; 351(9,115): 1,553.Google Scholar
Leunens, L, Celestin-Westreich, S, Bonduelle, M, Liebaers, I, Ponjaert-Kristoffersen, I. Follow-up of cognitive and motor development of 10-year-old singleton children born after ICSI compared with spontaneously conceived children. Hum Reprod 2008; 23(1): 105–11.Google Scholar
Ventimiglia, E, Capogrosso, P, Boeri, L et al. Infertility as a proxy of general male health: Results of a cross-sectional survey. Fertil Steril 2015; 104(1): 4855.Google Scholar
Eisenberg, ML, Li, S, Behr, B et al. Semen quality, infertility and mortality in the USA. Hum Reprod 2014; 29(7): 1,567–74.Google Scholar

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