Skip to main content Accessibility help

We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Close this message to accept cookies or find out how to manage your cookie settings.

Close cookie message
×
Hostname: page-component-8448b6f56d-c4f8m Total loading time: 0 Render date: 2024-04-18T15:42:23.294Z Has data issue: false hasContentIssue false

Chapter 15 - Eosinophilic lung disease

Published online by Cambridge University Press:  05 June 2014

By
Henry D. Tazelaar ,
Joanne L. Wright  and
Jay H. Ryu
Edited by
Philip Hasleton  and
Douglas B. Flieder
Philip Hasleton
Affiliation:
University of Manchester
Douglas B. Flieder
Affiliation:
Fox Chase Cancer Center, Philadelphia
Get access

Summary

Introduction

There are numerous diseases associated with pulmonary eosinophilia. They represent a heterogeneous group of diseases that, except for the presence of eosinophils, sometimes bear little clinical relationship to one another. The most common disease associated with eosinophilia is asthma, and the pathologist's role in the diagnosis is non-existent, except when there are complications. The most common diffuse disease associated with eosinophilia is chronic eosinophilic pneumonia, which may or may not be associated with asthma. These and other less common diseases are discussed in this chapter. Pulmonary Langerhans' cell histiocytosis (formerly known as eosinophilic granuloma) and hypersensitivity pneumonitis (extrinsic allergic alveolitis, which is rarely associated with tissue eosinophilia) are discussed in Chapters 34 and 12, respectively.

Introduction

Asthma is one of the commonest respiratory disorders and is characterized by airway hyperresponsiveness and inflammation. Over the past few decades, the prevalence of asthma has increased and affects as many as 300 million persons worldwide.

Type
Chapter
Information
Spencer's Pathology of the Lung , pp. 563 - 584
Publisher: Cambridge University Press
Print publication year: 2000

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

Katz, U, Shoenfeld, Y.Pulmonary eosinophilia. Clin Rev Allergy Immunol 2008;34(3):367–71.CrossRefGoogle ScholarPubMed
Wechsler, ME.Pulmonary eosinophilic syndromes. Immunol Allergy Clin North Am 2007;27(3):477–92.CrossRefGoogle ScholarPubMed
Fanta, CH.Asthma. New Engl J Med 2009;360(10):1002–14.CrossRefGoogle ScholarPubMed
Tarlo, SM, Balmes, J, Balkissoon, R, et al. Diagnosis and management of work-related asthma: American College Of Chest Physicians Consensus Statement.[erratum appears in Chest 2008;134(4):892]. Chest 2008;134(3 Suppl):1S–41S.CrossRefGoogle ScholarPubMed
Woods, AQ, Lynch, DA.Asthma: an imaging update. Radiol Clin North Am 2009;47(2):317–29.CrossRefGoogle Scholar
A plea to abandon asthma as a disease concept. Lancet 2006;368(9537):705.CrossRef
McLean, AN, Sproule, MW, Cowan, MD, Thomson, NC.High resolution computed tomography in asthma. Thorax 1998;53(4):308–14.CrossRefGoogle ScholarPubMed
Harmanci, E, Kebapci, M, Metintas, M, Ozkan, R.High-resolution computed tomography findings are correlated with disease severity in asthma. Respiration 2002;69(5):420–6.CrossRefGoogle ScholarPubMed
Takemura, M, Niimi, A, Minakuchi, M, et al. Bronchial dilatation in asthma: relation to clinical and sputum indices. Chest 2004;125(4):1352–8.CrossRefGoogle ScholarPubMed
Oguzulgen, IK, Kervan, F, Ozis, T, Turktas, H.The impact of bronchiectasis in clinical presentation of asthma. South Med J 2007;100(5):468–71.CrossRefGoogle Scholar
Kuyper, LM, Pare, PD, Hogg, JC, et al. Characterization of airway plugging in fatal asthma. Am J Med 2003;115(1):6–11.CrossRefGoogle ScholarPubMed
Saetta, M, Di Stefano, A, Rosina, C, Thiene, G, Fabbri, LM.Quantitative structural analysis of peripheral airways and arteries in sudden fatal asthma. Am Rev Respir Dis 1991;143(1):138–43.CrossRefGoogle ScholarPubMed
Aikawa, T, Shimura, S, Sasaki, H, Ebina, M, Takishima, T.Marked goblet cell hyperplasia with mucus accumulation in the airways of patients who died of severe acute asthma attack. Chest 1992;101(4):916–21.CrossRefGoogle ScholarPubMed
Hogg, J, Chu, F, Utokaparch, S, et al. The nature of small-airway obstruction in chronic obstructive pulmonary disease. N Engl J Med 2004;350(26):2645–53.CrossRefGoogle ScholarPubMed
Carroll, N, Elliot, J, Morton, A, James, A.The structure of large and small airways in nonfatal and fatal asthma. Am Rev Respir Dis 1993;147(2):405–10.CrossRefGoogle ScholarPubMed
Ordonez, CL, Khashayar, R, Wong, HH, et al. Mild and moderate asthma is associated with airway goblet cell hyperplasia and abnormalities in mucin gene expression. Am J Respir Crit Care Med 2001;163(2):517–23.CrossRefGoogle ScholarPubMed
Ordonez, C, Ferrando, R, Hyde, DM, Wong, HH, Fahy, JV.Epithelial desquamation in asthma: artifact or pathology?Am J Respir Crit Care Med 2000;162(6):2324–9.CrossRefGoogle ScholarPubMed
Laitinen, LA, Heino, M, Laitinen, A, Kava, T, Haahtela, T.Damage of the airway epithelium and bronchial reactivity in patients with asthma. Am Rev Respir Dis 1985;131(4):599–606.Google ScholarPubMed
Laitinen, A, Laitinen, LA.Airway morphology: epithelium/basement membrane. Am J Respir Crit Care Med 1994;150(5 Pt 2):S14–7.CrossRefGoogle ScholarPubMed
Jeffery, P, Wardlaw, A, Nelson, F, et al. Bronchial biopsies in asthma. An ultrastructural, quantitative study and correlation with hyperreactivity. Am Rev Respir Dis 1989;140(6):1745–53.CrossRefGoogle ScholarPubMed
Begueret, H, Berger, P, Vernejoux, JM, et al. Inflammation of bronchial smooth muscle in allergic asthma. Thorax 2007;62(1):8–15.CrossRefGoogle ScholarPubMed
Haraguchi, M, Shimura, S, Shirato, K.Morphologic aspects of airways of patients with pulmonary emphysema followed by bronchial asthma-like attack. Am J Respir Crit Care Med 1996;153(2):638–43.CrossRefGoogle ScholarPubMed
Wright, JL, Lawson, LM, Pare, PD, Wiggs, BJ, Kennedy, S, Hogg, JC.Morphology of peripheral airways in current smokers and ex-smokers. Am Rev Respir Dis 1983;127(4):474–7.CrossRefGoogle ScholarPubMed
Wright, JL, Lawson, LM, Pare, PD, et al. The detection of small airways disease. Am Rev Respir Dis 1984;129(6):989–94.Google ScholarPubMed
Paulsson, M.Basement membrane proteins: structure, assembly, and cellular interactions. Crit Rev Biochem Mol Biol 1992;27(1–2):93–127.Google ScholarPubMed
Roche, WR, Beasley, R, Williams, JH, Holgate, ST.Subepithelial fibrosis in the bronchi of asthmatics. Lancet 1989;1(8637):520–4.CrossRefGoogle ScholarPubMed
Roche, WR.Fibroblasts and asthma. Clin Exp Allergy 1991;21(5):545–8.CrossRefGoogle ScholarPubMed
Brightling, CE, Bradding, P, Symon, FA, et al. Mast-cell infiltration of airway smooth muscle in asthma. New Engl J Med 2002;346(22):1699–705.CrossRefGoogle ScholarPubMed
Saglani, S, Molyneux, C, Gong, H, et al. Ultrastructure of the reticular basement membrane in asthmatic adults, children and infants. Eur Respir J 2006;28(3):505–12.CrossRefGoogle ScholarPubMed
James, AL, Maxwell, PS, Pearce-Pinto, G, Elliot, JG, Carroll, NG.The relationship of reticular basement membrane thickness to airway wall remodeling in asthma. Am J Respir Crit Care Med 2002;166(12 Pt 1):1590–5.CrossRefGoogle ScholarPubMed
Bourdin, A, Neveu, D, Vachier, I, et al. Specificity of basement membrane thickening in severe asthma. J Allergy Clin Immunol 2007;119(6):1367–74.CrossRefGoogle ScholarPubMed
Wilson, JW, Li, X.The measurement of reticular basement membrane and submucosal collagen in the asthmatic airway. Clin Exp Allergy 1997;27(4):363–71.CrossRefGoogle ScholarPubMed
Chu, HW, Halliday, JL, Martin, RJ, et al. Collagen deposition in large airways may not differentiate severe asthma from milder forms of the disease. Am J Respir Crit Care Med 1998;158(6):1936–44.CrossRefGoogle Scholar
Barbato, A, Turato, G, Baraldo, S, et al. Airway inflammation in childhood asthma. Am J Respir Crit Care Med 2003;168(7):798–803.CrossRefGoogle ScholarPubMed
Bradley, BL, Azzawi, M, Jacobson, M, et al. Eosinophils, T-lymphocytes, mast cells, neutrophils, and macrophages in bronchial biopsy specimens from atopic subjects with asthma: comparison with biopsy specimens from atopic subjects without asthma and normal control subjects and relationship to bronchial hyperresponsiveness. J Allergy Clin Immunol 1991;88(4):661–74.CrossRefGoogle ScholarPubMed
Lacoste, JY, Bousquet, J, Chanez, P, et al. Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease. J Allergy Clin Immunol 1993;92(4):537–48.CrossRefGoogle ScholarPubMed
Beasley, R, Roche, WR, Roberts, JA, Holgate, ST.Cellular events in the bronchi in mild asthma and after bronchial provocation. Am Rev Respir Dis 1989;139(3):806–17.CrossRefGoogle ScholarPubMed
Perskvist, N, Edston, E.Differential accumulation of pulmonary and cardiac mast cell-subsets and eosinophils between fatal anaphylaxis and asthma death: a postmortem comparative study. Forensic Sci Int 2007;169(1):43–9.CrossRefGoogle ScholarPubMed
Azzawi, M, Johnston, PW, Majumdar, S, Kay, AB, Jeffery, PK.T lymphocytes and activated eosinophils in airway mucosa in fatal asthma and cystic fibrosis. Am Rev Respir Dis 1992;145(6):1477–82.CrossRefGoogle ScholarPubMed
Carroll, N, Cooke, C, James, A.The distribution of eosinophils and lymphocytes in the large and small airways of asthmatics. Eur Respir J 1997;10(2):292–300.CrossRefGoogle ScholarPubMed
Sur, S, Crotty, TB, Kephart, GM, et al. Sudden-onset fatal asthma. A distinct entity with few eosinophils and relatively more neutrophils in the airway submucosa?Am Rev Respir Dis 1993;148(3):713–9.CrossRefGoogle ScholarPubMed
Carroll, N, Carello, S, Cooke, C, James, A.Airway structure and inflammatory cells in fatal attacks of asthma. Eur Respir J 1996;9(4):709–15.CrossRefGoogle Scholar
Chetta, A, Zanini, A, Foresi, A, et al. Vascular endothelial growth factor up-regulation and bronchial wall remodelling in asthma. Clin Exp Allergy 2005;35(11):1437–42.CrossRefGoogle ScholarPubMed
Chetta, A, Zanini, A, Foresi, A, et al. Vascular component of airway remodeling in asthma is reduced by high dose of fluticasone. Am J Respir Crit Care Med 2003;167(5):751–7.CrossRefGoogle ScholarPubMed
Bradding, P, Walls, AF, Holgate, ST.The role of the mast cell in the pathophysiology of asthma. J Allergy Clin Immunol 2006;117(6):1277–84.CrossRefGoogle Scholar
Carroll, NG, Mutavdzic, S, James, AL.Distribution and degranulation of airway mast cells in normal and asthmatic subjects. Eur Respir J 2002;19(5):879–85.CrossRefGoogle ScholarPubMed
Liesker, JJ, Ten Hacken, NH, Rutgers, SR, et al. Mast cell numbers in airway smooth muscle and PC20AMP in asthma and COPD. Respir Med 2007;101(5):882–7.CrossRefGoogle ScholarPubMed
Vignola, AM, Chanez, P, Campbell, AM, et al. Airway inflammation in mild intermittent and in persistent asthma. Am J Respir Crit Care Med 1998;157(2):403–9.CrossRefGoogle ScholarPubMed
Faul, JL, Tormey, VJ, Leonard, C, et al. Lung immunopathology in cases of sudden asthma death. Eur Respir J 1997;10(2):301–7.CrossRefGoogle ScholarPubMed
O'Sullivan, S, Cormican, L, Faul, JL, et al. Activated, cytotoxic CD8(+) T lymphocytes contribute to the pathology of asthma death. Am J Respir Crit Care Med 2001;164(4):560–4.CrossRefGoogle ScholarPubMed
Lamb, JP, James, A, Carroll, N, et al. Reduced apoptosis of memory T-cells in the inner airway wall of mild and severe asthma. Eur Respir J 2005;26(2):265–70.CrossRefGoogle ScholarPubMed
Green, FH, Butt, JC, James, AL, Carroll, NG.Abnormalities of the bronchial arteries in asthma. Chest 2006;130(4):1025–33.CrossRefGoogle ScholarPubMed
Tanaka, H, Yamada, G, Saikai, T, et al. Increased airway vascularity in newly diagnosed asthma using a high-magnification bronchovideoscope. Am J Respir Crit Care Med 2003;168(12):1495–9.CrossRefGoogle ScholarPubMed
Barbato, A, Turato, G, Baraldo, S, et al. Epithelial damage and angiogenesis in the airways of children with asthma. Am J Respir Crit Care Med 2006;174(9):975–81.CrossRefGoogle ScholarPubMed
Salvato, G.Quantitative and morphological analysis of the vascular bed in bronchial biopsy specimens from asthmatic and non-asthmatic subjects. Thorax 2001;56(12):902–6.CrossRefGoogle ScholarPubMed
Li, X, Wilson, JW.Increased vascularity of the bronchial mucosa in mild asthma. Am J Respir Crit Care Med 1997;156(1):229–33.CrossRefGoogle ScholarPubMed
Carroll, NG, Cooke, C, James, AL.Bronchial blood vessel dimensions in asthma. Am J Respir Crit Care Med 1997;155(2):689–95.CrossRefGoogle ScholarPubMed
Kuwano, K, Bosken, CH, Pare, PD, et al. Small airways dimensions in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 1993;148(5):1220–5.CrossRefGoogle ScholarPubMed
Takizawa, T, Thurlbeck, WM.A comparative study of four methods of assessing the morphologic changes in chronic bronchitis. Am Rev Respir Dis 1971;103(6):774–83.Google ScholarPubMed
Dunnill, MS, Massarella, GR, Anderson, JA.A comparison of the quantitative anatomy of the bronchi in normal subjects, in status asthmaticus, in chronic bronchitis, and in emphysema. Thorax 1969;24(2):176–9.CrossRefGoogle ScholarPubMed
Hossain, S.Quantitative measurement of bronchial muscle in men with asthma. Am Rev Respir Med 1973;107:99–109.Google ScholarPubMed
Hossain, S, Heard, BE.Hyperplasia of bronchial muscle in chronic bronchitis. J Pathol 1970;101(2):171–84.CrossRefGoogle ScholarPubMed
Ebina, M, Takahashi, T, Chiba, T, Motomiya, M.Cellular hypertrophy and hyperplasia of airway smooth muscles underlying bronchial asthma. A 3-D morphometric study. Am Rev Respir Dis 1993;148(3):720–6.CrossRefGoogle ScholarPubMed
Ebina, M, Yaegashi, H, Chiba, R, et al. Hyperreactive site in the airway tree of asthmatic patients revealed by thickening of bronchial muscles. A morphometric study. Am Rev Respir Dis 1990;141(5 Pt 1):1327–32.CrossRefGoogle ScholarPubMed
Pare, PD, Wiggs, BR, James, A, Hogg, JC, Bosken, C.The comparative mechanics and morphology of airways in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 1991;143(5 Pt 1):1189–93.CrossRefGoogle ScholarPubMed
James, A, Pare, P, Hogg, J.The mechanics of airway narrowing in asthma. Am Rev Respir Dis 1989;139(1):242–6.CrossRefGoogle ScholarPubMed
Wiggs, BR, Bosken, C, Pare, PD, James, A, Hogg, JC.A model of airway narrowing in asthma and in chronic obstructive pulmonary disease. Am Rev Respir Dis 1992;145(6):1251–8.CrossRefGoogle ScholarPubMed
Jelihovsky, T.The structure of bronchial plugs in mucoid impaction, bronchocentric granulomatosis and asthma. Histopathology 1983;7(2):153–67.CrossRefGoogle ScholarPubMed
Ward, C, Walters, H.Airway wall remodelling: the influence of corticosteroids. Curr Opin Allergy Clin Immunol 2005;5(1):43–8.CrossRefGoogle ScholarPubMed
Capraz, F, Kunter, E, Cermik, H, Ilvan, A, Pocan, S.The effect of inhaled budesonide and formoterol on bronchial remodeling and HRCT features in young asthmatics. Lung 2007;185(2):89–96.CrossRefGoogle ScholarPubMed
Gibson, PG, Dolovich, J, Denburg, J, Ramsdale, EH, Hargreave, FE.Chronic cough: eosinophilic bronchitis without asthma. Lancet 1989;1(8651):1346–8.CrossRefGoogle ScholarPubMed
Gibson, PG, Fujimura, M, Niimi, A.Eosinophilic bronchitis: clinical manifestations and implications for treatment. Thorax 2002;57(2):178–82.CrossRefGoogle ScholarPubMed
Ayik, SO, Basoglu, OK, Erdinc, M, et al. Eosinophilic bronchitis as a cause of chronic cough. Respir Med 2003;97(6):695–701.CrossRefGoogle ScholarPubMed
Brightling, CE.Chronic cough due to nonasthmatic eosinophilic bronchitis: ACCP evidence-based clinical practice guidelines. Chest 2006;129(1 Suppl):116S–21S.CrossRefGoogle ScholarPubMed
Birring, SS, Berry, M, Brightling, CE, Pavord, ID.Eosinophilic bronchitis: clinical features, management and pathogenesis. Am J Respir Med 2003;2(2):169–73.CrossRefGoogle ScholarPubMed
Brightling, CE, Pavord, ID.Eosinophilic bronchitis: an important cause of prolonged cough. Ann Med 2000;32(7):446–51.CrossRefGoogle ScholarPubMed
Brightling, CE, Pavord, ID.Eosinophilic bronchitis – what is it and why is it important?Clin Exp Allergy 2000;30(1):4–6.CrossRefGoogle ScholarPubMed
Brightling, CE, Symon, FA, Birring, SS, et al. Comparison of airway immunopathology of eosinophilic bronchitis and asthma. Thorax 2003;58(6):528–32.CrossRefGoogle ScholarPubMed
Brightling, CE, Ward, R, Goh, KL, Wardlaw, AJ, Pavord, ID.Eosinophilic bronchitis is an important cause of chronic cough. Am J Respir Crit Care Med 1999;160(2):406–10.CrossRefGoogle ScholarPubMed
Brightling, CE, Ward, R, Woltmann, G, et al. Induced sputum inflammatory mediator concentrations in eosinophilic bronchitis and asthma. Am J Respir Crit Care Med 2000;162(3 Pt 1):878–82.CrossRefGoogle ScholarPubMed
Belda, J, Leigh, R, Parameswaran, K, et al. Induced sputum cell counts in healthy adults. Am J Respir Crit Care Med 2000;161(2 Pt 1):475–8.CrossRefGoogle ScholarPubMed
Berry, MA, Hargadon, B, McKenna, S, et al. Observational study of the natural history of eosinophilic bronchitis. Clin Exp Allergy 2005;35(5):598–601.CrossRefGoogle ScholarPubMed
Carrington, C, Addington, W, Goff, A, et al. Chronic eosinophilic pneumonia. N Engl J Med 1969;280(15):787–98.CrossRefGoogle ScholarPubMed
Liebow, A, Carrington, C.The eosinophilic pneumonias. Medicine (Baltimore) 1969;48(4):251–85.CrossRefGoogle ScholarPubMed
Alam, M, Burki, NK.Chronic eosinophilic pneumonia: a review. South Med J 2007;100(1):49–53.CrossRefGoogle ScholarPubMed
Marchand, E, Reynaud-Gaubert, M, Lauque, D, et al. Idiopathic chronic eosinophilic pneumonia. A clinical and follow-up study of 62 cases. The Groupe d'Etudes et de Recherche sur les Maladies “Orphelines” Pulmonaires (GERM“O”P). Medicine (Baltimore) 1998;77(5):299–312.CrossRefGoogle Scholar
Allen, J, Davis, W.Eosinophilic lung diseases. Am J Respir Crit Care Med 1994;150(5 Pt 1):1423–38.CrossRefGoogle ScholarPubMed
Jederlinic, P, Sicilian, L, Gaensler, E.Chronic eosinophilic pneumonia. A report of 19 cases and a review of the literature. Medicine (Baltimore) 1988;67(3):154–62.CrossRefGoogle Scholar
Marchand, E, Cordier, JF.Idiopathic chronic eosinophilic pneumonia. Semin Respir Crit Care Med 2006;27(2):134–41.CrossRefGoogle ScholarPubMed
Alberts, WM.Eosinophilic interstitial lung disease. Curr Opin Pulm Med 2004;10(5):419–24.CrossRefGoogle ScholarPubMed
Cottin, V, Cordier, JF.Eosinophilic pneumonias. Allergy 2005;60(7):841–57.CrossRefGoogle ScholarPubMed
Johkoh, T, Müller, NL, Akira, M, et al. Eosinophilic lung diseases: diagnostic accuracy of thin-section CT in 111 patients. Radiology 2000;216(3):773–80.CrossRefGoogle ScholarPubMed
Travis, W, Colby, T, Koss, M, et al. Non-neoplastic disorders of the lower respiratory tract. In: Atlas of Nontumor Pathology. First Series, Fascicle 2 ed. Washington DC: American Registry of Pathology and the Armed Forces Institute of Pathology, 2002.Google Scholar
Churg, A, Myers, J, Tazelaar, H, Wright, J, eds. Thurlbeck's Pathology of the Lung, 3rd ed. New York: Thieme Medical, 2005.Google Scholar
Katzenstein, A, Askin, F.Surgical Pathology of Non-neoplastic Lung Disease, 4th ed. Philadelphia: W.B. Saunders, 2006.Google Scholar
Leslie, KO, Wick, MR.Practical Pulmonary Pathology: a diagnostic approach. Philadelphia: Churchill Livingstone, 2005.Google Scholar
Bosken, C, Myers, J, Greenberger, P, et al. Pathologic features of allergic bronchopulmonary aspergillosis. Am J Surg Pathol 1988;12(3):216–22.CrossRefGoogle ScholarPubMed
Katzenstein, AL, Liebow, AA, Friedman, PJ.Bronchocentric granulomatosis, mucoid impaction, and hypersensitivity reactions to fungi. Am Rev Respir Dis 1975;111(4):497–537.Google ScholarPubMed
Lombard, CM, Tazelaar, HD, Krasne, DL.Pulmonary eosinophilia in coccidioidal infections. Chest 1987;91(5):734–6.CrossRefGoogle ScholarPubMed
Ryu, JH, Myers, JL, Swensen, SJ.Bronchiolar disorders. Am J Respir Crit Care Med 2003;168(11):1277–92.CrossRefGoogle ScholarPubMed
Carrington, C, Gaensler, E, Coutu, R, et al. Natural history and treated course of usual and desquamative interstitial pneumonia. New Engl J Med 1978;298(15):801–9.CrossRefGoogle ScholarPubMed
Yousem, SA.Eosinophilic pneumonia-like areas in idiopathic usual interstitial pneumonia. Mod Pathol 2000;13(12):1280–4.CrossRefGoogle ScholarPubMed
Elliott, MW, Newman, Taylor A J.Allergic bronchopulmonary aspergillosis. Clin Exp Allergy 1997;27 Suppl 1:55–9.CrossRefGoogle ScholarPubMed
Franquet, T, Muller, NL, Gimenez, A, et al. Spectrum of pulmonary aspergillosis: histologic, clinical, and radiologic findings. Radiographics 2001;21(4):825–37.CrossRefGoogle ScholarPubMed
Franquet, T, Muller, NL, Oikonomou, A, Flint, JD.Aspergillus infection of the airways: computed tomography and pathologic findings. J Comput Assist Tomogr 2004;28(1):10–6.CrossRefGoogle ScholarPubMed
Khan, AN, Jones, C, Macdonald, S.Bronchopulmonary aspergillosis: a review. Curr Probl Diagn Radiol 2003;32(4):156–68.CrossRefGoogle ScholarPubMed
Wark, PA, Gibson, PG.Allergic bronchopulmonary aspergillosis: new concepts of pathogenesis and treatment. Respirology 2001;6(1):1–7.CrossRefGoogle ScholarPubMed
Wardlaw, A, Geddes, DM.Allergic bronchopulmonary aspergillosis: a review. J R Soc Med 1992;85(12):747–51.Google ScholarPubMed
Agarwal, R.Allergic bronchopulmonary aspergillosis. Chest 2009;135(3):805–26.CrossRefGoogle ScholarPubMed
Kraemer, R, Delosea, N, Ballinari, P, Gallati, S, Crameri, R.Effect of allergic bronchopulmonary aspergillosis on lung function in children with cystic fibrosis. [see comment]Am J Respir Crit Care Med 2006;174(11):1211–20.CrossRefGoogle Scholar
Mroueh, S, Spock, A.Allergic bronchopulmonary aspergillosis in patients with cystic fibrosis. Chest 1994;105(1):32–6.CrossRefGoogle ScholarPubMed
Simmonds, EJ, Littlewood, JM, Evans, EG.Cystic fibrosis and allergic bronchopulmonary aspergillosis. Arch Dis Child 1990;65(5):507–11.CrossRefGoogle ScholarPubMed
Greenberger, PA, Patterson, R.Diagnosis and management of allergic bronchopulmonary aspergillosis. Ann Allergy 1986;56(6):444–8.Google ScholarPubMed
Cockrill, BA, Hales, CA.Allergic bronchopulmonary aspergillosis. Annu Rev Med 1999;50:303–16.CrossRefGoogle ScholarPubMed
Myers, JL.Bronchocentric granulomatosis. Disease or diagnosis? Chest 1989;96(1):3–4.CrossRefGoogle ScholarPubMed
Davis, WB, Wilson, HE, Wall, RL.Eosinophilic alveolitis in acute respiratory failure. A clinical marker for a non-infectious etiology. Chest 1986;90(1):7–10.CrossRefGoogle ScholarPubMed
Allen, J.Acute eosinophilic pneumonia. Semin Respir Crit Care Med 2006;27(2):142–7.CrossRefGoogle ScholarPubMed
Badesch, DB, King, TE, Schwarz, MI.Acute eosinophilic pneumonia: a hypersensitivity phenomenon?Am Rev Respir Dis 1989;139(1):249–52.CrossRefGoogle ScholarPubMed
Nishio, M, Ohata, M, Suruda, T, et al. Idiopathic acute eosinophilic pneumonia. Intern Med 1992;31(9):1139–43.CrossRefGoogle ScholarPubMed
Umeki, S, Soejima, R.Acute and chronic eosinophilic pneumonia: clinical evaluation and the criteria. Intern Med 1992;31(7):847–56.CrossRefGoogle ScholarPubMed
Philit, F, Etienne-Mastroianni, B, Parrot, A, et al. Idiopathic acute eosinophilic pneumonia: a study of 22 patients. Am J Respir Crit Care Med 2002;166(9):1235–9.CrossRefGoogle ScholarPubMed
Pope-Harman, AL, Davis, WB, Allen, ED, Christoforidis, AJ, Allen, JN.Acute eosinophilic pneumonia. A summary of 15 cases and review of the literature. Medicine (Baltimore) 1996;75(6):334–42.CrossRefGoogle ScholarPubMed
Shorr, AF, Scoville, SL, Cersovsky, SB, et al. Acute eosinophilic pneumonia among US military personnel deployed in or near Iraq. JAMA 2004;292(24):2997–3005.CrossRefGoogle ScholarPubMed
Al-Saieg, N, Moammar, O, Kartan, R.Flavored cigar smoking induces acute eosinophilic pneumonia. Chest 2007;131(4):1234–7.CrossRefGoogle ScholarPubMed
Miki, K, Miki, M, Nakamura, Y, et al. Early-phase neutrophilia in cigarette smoke-induced acute eosinophilic pneumonia. Intern Med 2003;42(9):839–45.Google ScholarPubMed
Nakajima, M, Manabe, T, Sasaki, T, Niki, Y, Matsushima, T.Acute eosinophilic pneumonia caused by cigarette smoking. Intern Med 2000;39(12):1131–2.CrossRefGoogle ScholarPubMed
Shiota, Y, Kawai, T, Matsumoto, H, et al. Acute eosinophilic pneumonia following cigarette smoking. Intern Med 2000;39(10):830–3.CrossRefGoogle ScholarPubMed
Watanabe, K, Fujimura, M, Kasahara, K, et al. Acute eosinophilic pneumonia following cigarette smoking: a case report including cigarette-smoking challenge test. Intern Med 2002;41(11):1016–20.CrossRefGoogle ScholarPubMed
Tazelaar, H, Linz, L, Colby, T, et al. Acute eosinophilic pneumonia: histopathologic findings in nine patients. Am J Respir Crit Care Med 1997;155(1):296–302.CrossRefGoogle ScholarPubMed
Mochimaru, H, Kawamoto, M, Fukuda, Y, Kudoh, S.Clinicopathological differences between acute and chronic eosinophilic pneumonia. Respirology 2005;10(1):76–85.CrossRefGoogle ScholarPubMed
Sharma, OP, Bethlem, EP.The pulmonary infiltration with eosinophilia syndrome. Curr Opin Pulm Med 1996;2(5):380–9.CrossRefGoogle ScholarPubMed
Cottin, V, Frognier, R, Monnot, H, et al. Chronic eosinophilic pneumonia after radiation therapy for breast cancer. Eur Respir J 2004;23(1):9–13.CrossRefGoogle ScholarPubMed
Uchiyama, H, Suda, T, Nakamura, Y, et al. Alterations in smoking habits are associated with acute eosinophilic pneumonia. Chest 2008;133(5):1174–80.CrossRefGoogle ScholarPubMed
Allen, JN.Drug-induced eosinophilic lung disease. Clin Chest Med 2004;25(1):77–88.CrossRefGoogle ScholarPubMed
Keogh, KA, Specks, U.Churg-Strauss syndrome: clinical presentation, antineutrophil cytoplasmic antibodies, and leukotriene receptor antagonists. Am J Med 2003;115(4):284–90.CrossRefGoogle ScholarPubMed
Grantham, JG, Meadows, JA, Gleich, GJ.Chronic eosinophilic pneumonia. Evidence for eosinophil degranulation and release of major basic protein. Am J Med 1986;80(1):89–94.CrossRefGoogle ScholarPubMed
Allen, JN, Davis, WB, Pacht, ER.Diagnostic significance of increased bronchoalveolar lavage fluid eosinophils. Am Rev Respir Dis 1990;142(3):642–7.CrossRefGoogle ScholarPubMed
Toyoshima, M, Sato, A, Taniguchi, M, et al. [A case of eosinophilic pneumonia caused by inhalation of nickel dusts]. Nihon Kyobu Shikkan Gakkai Zasshi. Jap J Thorac Dis 1994;32(5):480–4.Google Scholar
Potter, MB, Fincher, RK, Finger, DR.Eosinophilia in Wegener's granulomatosis. Chest 1999;116(5):1480–3.CrossRefGoogle ScholarPubMed
Yousem, S, Lombard, C.The eosinophilic variant of Wegener's granulomatosis. Hum Pathol 1988;19(6):682–8.CrossRefGoogle ScholarPubMed
Luna, E, Tomashefski, JF, Brown, D, Clarke, RE, Kleinerman, J.Reactive eosinophilic pulmonary vascular infiltration in patients with spontaneous pneumothorax. Am J Surg Pathol 1994;18(2):195–9.CrossRefGoogle ScholarPubMed
McDonnell, TJ, Crouch, EC, Gonzalez, JG.Reactive eosinophilic pleuritis. A sequela of pneumothorax in pulmonary eosinophilic granuloma. Am J Clin Pathol 1989;91(1):107–11.CrossRefGoogle ScholarPubMed
Webber, D, Tron, V, Askin, F, Churg, A.S-100 staining in the diagnosis of eosinophilic granuloma of lung. Am J Clin Pathol 1985;84(4):447–53.CrossRefGoogle Scholar
Coax, WA.Reactive eosinophilic pleuritis and pleural effusion. Arch Pathol Lab Med 1977;101(10):555.Google ScholarPubMed
Askin, FB, McCann, BG, Kuhn, C.Reactive eosinophilic pleuritis: a lesion to be distinguished from pulmonary eosinophilic granuloma. Arch Pathol Lab Med 1977;101(4):187–91.Google ScholarPubMed
Nasta P, DA, Cattane, A, Chiodera, A, Casari, S.Acute histoplasmosis in spelunkers returning from Mato Grosso, Peru. J Travel Med 1997;4(4):176–8.CrossRefGoogle ScholarPubMed
Rom, WN, Weiden, M, Garcia, R, et al. Acute eosinophilic pneumonia in a New York City firefighter exposed to World Trade Center dust. [see comment]Am J Respir Crit Care Med 2002;166(6):797–800.CrossRefGoogle Scholar
Hirai, K, Yamazaki, Y, Okada, K, Furuta, S, Kubo, K.Acute eosinophilic pneumonia associated with smoke from fireworks. Intern Med 2000;39(5):401–3.CrossRefGoogle ScholarPubMed
Vassallo, R, Ryu, JH.Tobacco smoke-related diffuse lung diseases. Semin Respir Crit Care Med 2008;29(6):643–50.CrossRefGoogle ScholarPubMed

Save book to Kindle

To save this book to your Kindle, first ensure coreplatform@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about saving to your Kindle.

Note you can select to save to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be saved to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Available formats
×

Save book to Dropbox

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Dropbox.

Available formats
×

Save book to Google Drive

To save content items to your account, please confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your account. Find out more about saving content to Google Drive.

Available formats
×