Book contents
- Personalized Anaesthesia
- Personalized Anaesthesia
- Copyright page
- Contents
- Contributors
- Foreword
- Introduction
- Section 1 Basic Principles
- Section 2 Targeting Effects
- 7 Hypnotic Effect: Inducing Unconsciousness and Emergence from Anaesthesia
- 8 Analgesia: Effects on Response to Nociceptive Stimulation
- 9 Personalized Sedation and Analgesia
- 10 Respiratory Depression
- 11 Immobility
- 12 Effects on Brain Function
- 13 Targeted and Individualized Perioperative Medicine for Cognitive Dysfunction
- 14 Cardiac and Haemodynamic Function
- 15 Effects of Anaesthesia on Thermoregulation
- 16 Effects of Perioperative Management on Kidney Function
- 17 Effects on Liver Function
- 18 Effects on Fluid Balance
- 19 Ventilation during General Anaesthesia
- 20 Epilogue: Artificial Intelligence Methods
- Index
- References
16 - Effects of Perioperative Management on Kidney Function
from Section 2 - Targeting Effects
Published online by Cambridge University Press: 03 December 2019
Book contents
- Personalized Anaesthesia
- Personalized Anaesthesia
- Copyright page
- Contents
- Contributors
- Foreword
- Introduction
- Section 1 Basic Principles
- Section 2 Targeting Effects
- 7 Hypnotic Effect: Inducing Unconsciousness and Emergence from Anaesthesia
- 8 Analgesia: Effects on Response to Nociceptive Stimulation
- 9 Personalized Sedation and Analgesia
- 10 Respiratory Depression
- 11 Immobility
- 12 Effects on Brain Function
- 13 Targeted and Individualized Perioperative Medicine for Cognitive Dysfunction
- 14 Cardiac and Haemodynamic Function
- 15 Effects of Anaesthesia on Thermoregulation
- 16 Effects of Perioperative Management on Kidney Function
- 17 Effects on Liver Function
- 18 Effects on Fluid Balance
- 19 Ventilation during General Anaesthesia
- 20 Epilogue: Artificial Intelligence Methods
- Index
- References
Summary
Normal kidney function is essential to maintain whole body homeostasis. An acute decline in kidney function, ‘acute kidney injury’ (AKI), is in and by itself a major cause of perioperative morbidity and mortality. Maintaining preexisting kidney function therefore is a key task of the anaesthesiologist in the perioperative period [1].
Studies on perioperative AKI (including worsening of chronic renal failure) have mainly focused on the postoperative/ICU setting because (1) renal dysfunction does not alter intraoperative haemodynamics or oxygenation (provided a neutral fluid balance is maintained); (2) we lack readily available biomarkers to monitor intraoperative renal function (intraoperative oliguria is a poor marker of AKI, and creatinine value takes hours to rise); (3) medical treatment of AKI is mainly performed in the ICU (managing fluid overload, hyperkalaemia, drug dosing adjustments or renal replacement therapies); (4) patients at risk for AKI are likely to be admitted to the ICU postoperatively.
- Type
- Chapter
- Information
- Personalized AnaesthesiaTargeting Physiological Systems for Optimal Effect, pp. 238 - 244Publisher: Cambridge University PressPrint publication year: 2020
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