Section 2 - General Health and Illness
Published online by Cambridge University Press: 06 January 2018
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- Perioperative Care of the Elderly Patient , pp. 25 - 98Publisher: Cambridge University PressPrint publication year: 2018
References
References
Aronow, WS, Fleg, JL, Pepine, CJ, et al. ACCF/AHA 2011 expert consensus document on hypertension in the elderly: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents developed in collaboration with the American Academy of Neurology, American Geriatrics Society, American Society for Preventive Cardiology, American Society of Hypertension, American Society of Nephrology, Association of Black Cardiologists, and European Society of Hypertension. J Am Soc Hypertens. 2011; 5(4):259–352.CrossRefGoogle Scholar
Egan, BM, Zhao, Y, Axon, RN. US trends in prevalence, awareness, treatment, and control of hypertension, 1988-2008. JAMA. 2010; 303(20):2043–2050.CrossRefGoogle ScholarPubMed
Vasan, RS, Beiser, A, Seshadri, S, et al. Residual lifetime risk for developing hypertension in middle-aged women and men: The Framingham Heart Study. JAMA. 2002; 287(8):1003–1010.CrossRefGoogle ScholarPubMed
Prys-Roberts, C. Isolated systolic hypertension: pressure on the anaesthetist? Anaesthesia. 2001; 56(6):505–510.Google Scholar
Staessen, JA, Fagard, R, Thijs, L, et al. Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension. The Systolic Hypertension in Europe (Syst-Eur) Trial Investigators. Lancet. 1997; 350(9080):757–764.Google Scholar
Gasowski, J, Fagard, RH, Staessen, JA, et al. Pulsatile blood pressure component as predictor of mortality in hypertension: a meta-analysis of clinical trial control groups. J Hypertens. 2002; 20(1):145–151.Google Scholar
SHEP Cooperative Research Group. Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). JAMA. 1991; 265(24):3255–3264.CrossRefGoogle Scholar
Aronson, S, Boisvert, D, Lapp, W. Isolated systolic hypertension is associated with adverse outcomes from coronary artery bypass grafting surgery. Anesth Analg. 2002; 94(5):1079–1084, table of contents.CrossRefGoogle ScholarPubMed
Karapanayiotides, T, Meuli, R, Devuyst, G, et al. Postcarotid endarterectomy hyperperfusion or reperfusion syndrome. Stroke. 2005; 36(1):21–26.Google Scholar
Browner, WS, Li, J, Mangano, DT; The Study of Perioperative Ischemia Research Group. In-hospital and long-term mortality in male veterans following noncardiac surgery. JAMA. 1992; 268(2):228–232.Google Scholar
Kheterpal, S, Tremper, KK, Englesbe, MJ, et al. Predictors of postoperative acute renal failure after noncardiac surgery in patients with previously normal renal function. Anesthesiology. 2007; 107(6):892–902.Google Scholar
Sear, JW. Perioperative control of hypertension: when will it adversely affect perioperative outcome? Curr Hypertens Rep. 2008; 10(6):480–487.CrossRefGoogle ScholarPubMed
Staessen, JA, Gasowski, J, Wang, JG, et al. Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials. Lancet. 2000; 355(9207):865–872.Google Scholar
Perry, HM Jr., Davis, BR, Price, TR, et al. Effect of treating isolated systolic hypertension on the risk of developing various types and subtypes of stroke: the Systolic Hypertension in the Elderly Program (SHEP). JAMA. 2000; 284(4):465–471.CrossRefGoogle ScholarPubMed
Beckett, NS, Peters, R, Fletcher, AE, et al. Treatment of hypertension in patients 80 years of age or older. N Engl J Med. 2008; 358(18):1887–1898.CrossRefGoogle ScholarPubMed
Klingbeil, AU, Schneider, M, Martus, P, Messerli, FH, Schmieder, RE. A meta-analysis of the effects of treatment on left ventricular mass in essential hypertension. Am J Med. 2003; 115(1):41–46.CrossRefGoogle ScholarPubMed
Wachtell, K, Bella, JN, Rokkedal, J, et al. Change in diastolic left ventricular filling after one year of antihypertensive treatment: The Losartan Intervention For Endpoint Reduction in Hypertension (LIFE) Study. Circulation. 2002; 105(9):1071–1076.CrossRefGoogle ScholarPubMed
Howell, SJ, Sear, JW, Foex, P. Hypertension, hypertensive heart disease and perioperative cardiac risk. Br J Anaesth. 2004; 92(4):570–583.Google Scholar
Weksler, N, Klein, M, Szendro, G, et al. The dilemma of immediate preoperative hypertension: to treat and operate, or to postpone surgery? J Clin Anesth. 2003; 15(3):179–183.Google Scholar
Wang, JG, Staessen, JA. Improved outcomes with antihypertensive medication in the elderly with isolated systolic hypertension. Drugs Aging. 2001; 18(5):345–353.Google Scholar
Kim, BS, Bae, JN, Cho, MJ. Depressive symptoms in elderly adults with hypotension: different associations with positive and negative affect. J Affect Disord. 2010; 127(1–3):359–364.CrossRefGoogle ScholarPubMed
Devereaux, PJ, Yang, H, Yusuf, S, et al. Effects of extended-release metoprolol succinate in patients undergoing non-cardiac surgery (POISE trial): a randomised controlled trial. Lancet. 2008; 371(9627):1839–1847.Google Scholar
Foex, P, Sear, JW. The surgical hypertensive patient. Cont Edu in Anaesth, Crit Care Pain. 2004; 4:139–143.Google Scholar
Eagle, KA, Berger, PB, Calkins, H, et al. ACC/AHA guideline update for perioperative cardiovascular evaluation for noncardiac surgery: executive summary a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Update the 1996 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Circulation. 2002; 105(10):1257–1267.Google Scholar
Fleisher, LA, Beckman, JA, Brown, KA, et al. ACC/AHA 2007 guidelines on perioperative cardiovascular evaluation and care for noncardiac surgery: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Writing Committee to Revise the 2002 Guidelines on Perioperative Cardiovascular Evaluation for Noncardiac Surgery). Anes Analg. 2008; 106(3):685–712.CrossRefGoogle Scholar
Fleisher, LA, Fleischmann, KE, Auerbach, AD, et al. 2014 ACC/AHA guideline on perioperative cardiovascular evaluation and management of patients undergoing noncardiac surgery: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2014; 64(22):e77–e137.Google Scholar
Goldman, L, Caldera, DL, Nussbaum, SR, et al. Multifactorial index of cardiac risk in noncardiac surgical procedures. N Engl J Med. 1977; 297(16):845–850.CrossRefGoogle ScholarPubMed
Lee, TH, Marcantonio, ER, Mangione, CM, et al. Derivation and prospective validation of a simple index for prediction of cardiac risk of major noncardiac surgery. Circulation. 1999; 100(10):1043–1049.Google Scholar
Gupta, PK, Gupta, H, Sundaram, A, et al. Development and validation of a risk calculator for prediction of cardiac risk after surgery. Circulation. 2011; 124(4):381–387.CrossRefGoogle ScholarPubMed
Collaboration BPLTT. Effects of angiotensin converting enzyme inhibitors, calcium antagonists and other blood pressure lowering drugs on mortality and major cardiovascular morbidity: first cycle of analyses from a program of prospectively designed collaborative overviews of major randomised trials. Lancet. 2000; 355(9246):1955–1964.Google Scholar
Fleisher, LA. Preoperative evaluation of the patient with hypertension. JAMA. 2002; 287(16):2043–2046.CrossRefGoogle ScholarPubMed
Coriat, P, Richer, C, Douraki, T, et al. Influence of chronic angiotensin-converting enzyme inhibition on anesthetic induction. Anesthesiology. 1994; 81(2):299–307.CrossRefGoogle ScholarPubMed
Bertrand, M, Godet, G, Meersschaert, K, et al. Should the angiotensin II antagonists be discontinued before surgery? Anesth Analg. 2001; 92(1):26–30.CrossRefGoogle ScholarPubMed
Ryckwaert, F, Colson, P. Hemodynamic effects of anesthesia in patients with ischemic heart failure chronically treated with angiotensin-converting enzyme inhibitors. Anesth Analg. 1997; 84(5):945–949.CrossRefGoogle ScholarPubMed
Licker, M, Schweizer, A, Hohn, L, Farinelli, C, Morel, DR. Cardiovascular responses to anesthetic induction in patients chronically treated with angiotensin-converting enzyme inhibitors. Can J Anaesth. 2000; 47(5):433–440.Google Scholar
Turan, A, You, J, Shiba, A, et al. Angiotensin converting enzyme inhibitors are not associated with respiratory complications or mortality after noncardiac surgery. Anesth Analg. 2012; 114(3):552–560.Google Scholar
Wijeysundera, DN, Beattie, WS. Calcium channel blockers for reducing cardiac morbidity after noncardiac surgery: a meta-analysis. Anesth Analg. 2003; 97(3):634–641.Google Scholar
Wijeysundera, DN, Beattie, WS, Rao, V, Karski, J. Calcium antagonists reduce cardiovascular complications after cardiac surgery: a meta-analysis. J Am Coll Cardiol. 2003; 41(9):1496–1505.Google Scholar
Wildburger, NC, Lin-Ye, A, Baird, MA, Lei, D, Bao, J. Neuroprotective effects of blockers for T-type calcium channels. Mol Neurodegener. 2009; 4:44.Google Scholar
Lopez-Arrieta, JM, Birks, J. Nimodipine for primary degenerative, mixed and vascular dementia. Cochrane Database Syst Rev. 2002(3):CD000147.Google ScholarPubMed
Khan, NA, Campbell, NR, Frost, SD, et al. Risk of intraoperative hypotension with loop diuretics: a randomized controlled trial. Am J Med. 2010; 123(11):1059. e1–8.CrossRefGoogle ScholarPubMed
Wallace, AW, Au, S, Cason, BA. Association of the pattern of use of perioperative beta-blockade and postoperative mortality. Anesthesiology. 2010; 113(4):794–805.Google Scholar
Shammash, JB, Trost, JC, Gold, JM, et al. Perioperative beta-blocker withdrawal and mortality in vascular surgical patients. Am Heart J. 2001; 141(1):148–153.Google Scholar
Bell, CM, Hatch, WV, Fischer, HD, et al. Association between tamsulosin and serious ophthalmic adverse events in older men following cataract surgery. JAMA. 2009; 301(19):1991–1996.Google Scholar
Hollevoet, I, Herregods, S, Vereecke, H, Vandermeulen, E, Herregods, L. Medication in the perioperative period: stop or continue? A review. Acta Anaesthesiol Belg. 2011; 62(4):193–201.Google Scholar
Taylor, AL, Ziesche, S, Yancy, C, et al. Combination of isosorbide dinitrate and hydralazine in blacks with heart failure. N Engl J Med. 2004; 351(20):2049–2057.CrossRefGoogle ScholarPubMed
Xhignesse, P, Saint-Remy, A, Krzesinski, JM. [Management of arterial hypertension in the elderly]. Rev Med Liege. 2014; 69(5-6):294–300.Google ScholarPubMed
Ogihara, T, Saruta, T, Rakugi, H, et al. Target blood pressure for treatment of isolated systolic hypertension in the elderly: valsartan in elderly isolated systolic hypertension study. Hypertension. 2010; 56(2):196–202.Google Scholar
James, PA, Oparil, S, Carter, BL, et al. 2014 evidence-based guideline for the management of high blood pressure in adults: report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA. 2014 311(5):507–520.Google Scholar
Arguedas, JA, Leiva, V, Wright, JM. Blood pressure targets for hypertension in people with diabetes mellitus. Cochrane Database Syst Rev. 2013(10):CD008277.Google Scholar
Rhoney, D, Peacock, WF. Intravenous therapy for hypertensive emergencies, Part 1. Am J Health Syst Pharm. 2009; 66(15):1343–1352.CrossRefGoogle ScholarPubMed
Young, JH, Klag, MJ, Muntner, P, et al. Blood pressure and decline in kidney function: findings from the Systolic Hypertension in the Elderly Program (SHEP). J Am Soc Nephrol. 2002; 13(11):2776–2782.Google Scholar
Helfman, SM, Gold, MI, DeLisser, EA, Herrington, CA. Which drug prevents tachycardia and hypertension associated with tracheal intubation: lidocaine, fentanyl, or esmolol? Anesth Analg. 1991; 72(4):482–486.CrossRefGoogle ScholarPubMed
Rose, DK, Cohen, MM, DeBoer, DP. Cardiovascular events in the postanesthesia care unit: contribution of risk factors. Anesthesiology. 1996; 84(4):772–781.Google Scholar
Varon, J, Marik, PE. Perioperative hypertension management. Vasc Health Risk Manag. 2008; 4(3):615–627.Google Scholar
References
Yancy, CW, Jessup, M, Bozkurt, B, et al. 2013 ACCF/AHA guideline for the management of heart failure: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. Circulation. 2013; 128(16):e240–e327.Google Scholar
Liu, L, Eisen, HJ. Epidemiology of heart failure and scope of the problem. Cardiol Clin. 2014; 32(1):1–8, vii.CrossRefGoogle ScholarPubMed
Holdright, DR, Dayer, M, Cowie, MR. Heart failure: diagnosis and healthcare burden. Clin Med. 2004; 4(1):13–18.Google Scholar
Wong, CY, Chaudhry, SI, Desai, MM, Krumholz, HM. Trends in comorbidity, disability, and polypharmacy in heart failure. Am J Med. 2011; 124(2):136–143.Google Scholar
Levy, D, Kenchaiah, S, Larson, MG, et al. Long-term trends in the incidence of and survival with heart failure. N Engl J Med. 2002; 347(18):1397–1402.Google Scholar
Upshaw, J, Kiernan, MS. Preoperative cardiac risk assessment for noncardiac surgery in patients with heart failure. Curr Heart Fail Rep. 2013; 10(2):147–156.Google Scholar
Swedberg, K, Cleland, J, Cowie, MR, et al. Successful treatment of heart failure with devices requires collaboration. Eur J Heart Fail. 2008; 10(12):1229–1235.CrossRefGoogle ScholarPubMed
Bardia, A, Montealegre-Gallegos, M, Mahmood, F, et al. Left atrial size: an underappreciated perioperative cardiac risk factor. J Cardiothor Vasc Anesth. 2014; 28(6):1624–1632.Google Scholar
Roger, VL, Weston, SA, Redfield, MM, et al. Trends in heart failure incidence and survival in a community-based population. JAMA. 2004; 292(3):344–350.Google Scholar
Matyal, R. Newly appreciated pathophysiology of ischemic heart disease in women mandates changes in perioperative management: a core review. Anesth Analg. 2008; 107(1):37–50.Google Scholar
Meyer, S, van der Meer, P, Massie, BM, et al. Sex-specific acute heart failure phenotypes and outcomes from PROTECT. Eur J Heart Fail. 2013; 15(12):1374–1381.CrossRefGoogle ScholarPubMed
Sharkey, SW, Lesser, JR, Zenovich, AG, et al. Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation. 2005; 111(4):472–479.Google Scholar
Akashi, YJ, Goldstein, DS, Barbaro, G, Ueyama, T. Takotsubo cardiomyopathy: a new form of acute, reversible heart failure. Circulation. 2008; 118(25):2754–2762.Google Scholar
Cowie, MR, Wood, DA, Coats, AJ, et al. Incidence and aetiology of heart failure: a population-based study. Eur Heart J. 1999; 20(6):421–428.CrossRefGoogle ScholarPubMed
Dolgin, M. Nomenclature and Criteria for Diagnosis of Diseases of the Heart and Great Vessels. New York, Little, Brown Medical Division; 1994.Google Scholar
Hunt, SA, Abraham, WT, Chin, MH, et al. 2009 focused update incorporated into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines developed in collaboration with the International Society for Heart and Lung Transplantation. J Am Coll Cardiol. 2009; 53(15):e1–e90.CrossRefGoogle Scholar
Farmakis, D, Parissis, J, Lekakis, J, Filippatos, G. Acute heart failure: epidemiology, risk factors, and prevention. Rev Esp Cardiol (Engl Ed). 2015; 68(3):245–248.Google Scholar
Schocken, DD, Benjamin, EJ, Fonarow, GC, et al. Prevention of heart failure: a scientific statement from the American Heart Association Councils on Epidemiology and Prevention, Clinical Cardiology, Cardiovascular Nursing, and High Blood Pressure Research; Quality of Care and Outcomes Research Interdisciplinary Working Group; and Functional Genomics and Translational Biology Interdisciplinary Working Group. Circulation. 2008; 117(19):2544–2565.Google Scholar
Poldermans, D, Bax, JJ, Boersma, E, et al. Guidelines for pre-operative cardiac risk assessment and perioperative cardiac management in non-cardiac surgery. Eur Heart J. 2009; 30(22):2769–2812.Google Scholar
Garbade, J, Barten, MJ, Bittner, HB, Mohr, FW. Heart transplantation and left ventricular assist device therapy: two comparable options in end-stage heart failure? Clin Cardiol. 2013; 36(7):378–382.Google Scholar
Rose, EA, Gelijns, AC, Moskowitz, AJ, et al. Long-term use of a left ventricular assist device for end-stage heart failure. N Engl J Med. 2001; 345(20):1435–1443.CrossRefGoogle ScholarPubMed
Slaughter, MS, Rogers, JG, Milano, CA, et al. Advanced heart failure treated with continuous-flow left ventricular assist device. N Engl J Med. 2009; 361(23):2241–2251.Google Scholar
Rathore, SS, Curtis, JP, Wang, Y, Bristow, MR, Krumholz, HM. Association of serum digoxin concentration and outcomes in patients with heart failure. JAMA. 2003; 289(7):871–878.Google Scholar
Simon, T, Mary-Krause, M, Funck-Brentano, C, Jaillon, P. Sex differences in the prognosis of congestive heart failure: results from the Cardiac Insufficiency Bisoprolol Study (CIBIS II). Circulation. 2001; 103(3):375–380.Google Scholar
Modena, MG, Muia, N, Aveta, P, Molinari, R, Rossi, R. Effects of transdermal 17beta-estradiol on left ventricular anatomy and performance in hypertensive women. Hypertension. 1999; 34(5):1041–1046.Google Scholar
Rossouw, JE, Prentice, RL, Manson, JE, et al. Postmenopausal hormone therapy and risk of cardiovascular disease by age and years since menopause. JAMA. 2007; 297(13):1465–1477.Google Scholar
Hernandez, AF, Whellan, DJ, Stroud, S, et al. Outcomes in heart failure patients after major noncardiac surgery. J Am Coll Cardiol. 2004; 44(7):1446–1453.CrossRefGoogle ScholarPubMed
Healy, KO, Waksmonski, CA, Altman, RK, et al. Perioperative outcome and long-term mortality for heart failure patients undergoing intermediate- and high-risk noncardiac surgery: impact of left ventricular ejection fraction. Congest Heart Fail. 2010; 16(2):45–49.Google Scholar
Stoelting, RK, Dierdorf, SF, McCammon, RL. Anesthesia and Co-Existing Disease. London, Churchill Livingston, 2002.Google Scholar
References
World Health Organization. Dementia fact sheet No. 362. April 2012. Available from: www.who.int/mediacentre/factsheets/fs362/en/ (Accessed June 30, 2017).Google Scholar
Dong, Y, Lee, WY, Basri, NA, et al. The Montreal Cognitive Assessment is superior to the Mini-Mental State Examination in detecting patients at higher risk of dementia. Int Psychogeriatr. 2012; 24(11):1749–1755.CrossRefGoogle Scholar
Knopman, DS, DeKosky, ST, Cummings, JL, et al. Practice parameter: diagnosis of dementia (an evidence-based review). Report of the Quality Standards Subcommittee of the American Academy of Neurology. Neurology. 2001; 56:1143.Google Scholar
American Geriatrics Society. A guide to dementia diagnosis and treatment. Available from: unmfm.pbworks.com/f/American+Geriatric+Society+Dementia+Diagnosis+03-09-11.pdf (Accessed July 19, 2017).Google Scholar
Diniz, BS, Butters, MA, Albert, SM, et al. Late-life depression and risk of vascular dementia and Alzheimer's disease: systematic review and meta-analysis of community-based cohort studies. Br J Psychiatry. 2013; 202:329.Google Scholar
Barnes De, Yaffe K, Byers, AL, et al. Midlife vs late-life depressive symptoms and risk of dementia: differential effects of Alzheimer disease and vascular dementia. Arch Gen Psychiatry. 2012; 69:493.Google Scholar
Cummings, JL, Isaacson, RS, Schmitt, FA, Velting, DM. A practical algorithm for managing Alzheimer's disease: what, when, and why? Ann Clin Transl Neurol. 2015; 2(3):307–323.Google Scholar
Chi, S, Yu, JT, Tan, MS, Tan, L. Depression in Alzheimer's disease: epidemiology, mechanisms, and management. J Alzheimer's Dis. 2014; 42(3):739–755.Google Scholar
Staedtler, AV, Nunez, D. Nonpharmacologic therapy for the management of neuropsychiatric symptoms of Alzheimer's disease: linking evidence to practice. Worldviews Evid Based Nurs. 2015; 12(2):108–115.Google Scholar
Cummings, J, Froelich, L, Black, SE, et al. Randomized, double-blind, parallel-group, 48-week study for efficacy and safety of a higher-dose rivastigmine patch (15 vs. 10 cm2) in Alzheimer's disease. Dement Geriatr Cogn Disord. 2012; 33:341–353.Google Scholar
Birks, J. Cholinesterase inhibitors for Alzheimer's disease. Cochrane Database Syst Rev. 2006(1):CD005593.Google Scholar
Raina, P, Santaguida, P, Ismaila, A, et al. Effectiveness of cholinesterase inhibitors and memantine for treating dementia: evidence review for a clinical practice guideline. Ann Intern Med. 2008; 148:379–397.Google Scholar
Hogan, DB. Long-term efficacy and toxicity of cholinesterase inhibitors in the treatment of Alzheimer disease. Can J Psychiatry. 2014; 59(12):618–623.Google Scholar
Herrmann, N, Lanctot, KL, Hogan, DB. Pharmacological recommendations for the symptomatic treatment of dementia: the Canadian Consensus Conference on the Diagnosis and Treatment of Dementia 2012. Alzheimer Res Ther. 2013; 5(Suppl 1):S5.CrossRefGoogle ScholarPubMed
Reisberg, B, Doody, R, Stoffler, A, et al. Memantine in moderate-to-severe Alzheimer's disease. N Engl J Med. 2003; 348:1333–1341.Google Scholar
Grossberg, GT, Manes, F, Allegri, RF et al. The safety, tolerability, and efficacy of once-daily memantine (28 mg): a multinational, randomized, double-blind, placebo-controlled trial in patients with moderate-to-severe Alzheimer's disease taking cholinesterase inhibitors. CNS Drugs. 2013; 27:469–478.Google Scholar
Schwarz, S, Froelich, L, Burns, A. Pharmacologic treatment of dementia. Curr Opin Psychiatry. 2012; 25(6):542–550.Google Scholar
Lo, D, Grossberg, GT. Use of memantine for the treatment of dementia. Expert Rev Neurother. 2011; 11(1):1359–1370.Google Scholar
Lobo, A, Launer, LJ, Fratiglioni, L, et al. Prevalence of dementia and major subtypes in Europe: a collaborative study of population-based cohorts. Neurologic Diseases in the Elderly Research Group. Neurology. 2000; 54:S4.Google Scholar
Hebert, R, Brayne, C. Epidemiology of vascular dementia. Neuroepidemiology 1995; 14:240.CrossRefGoogle ScholarPubMed
Ruitenberg, A, Ott, A, van Swieten, JC, et al. Incidence of dementia: does gender make a difference? Neurobiol Aging. 2001; 22(4):575–580.Google Scholar
Smith, EE, Schneider, JA, Wardlaw, JM, Greenberg, SM. Cerebral microinfarcts: the invisible lesions. Lancet Neurol. 2012; 11(3):272–282.Google Scholar
Chui, H. Vascular dementia, a new beginning: shifting focus from clinical phenotype to ischemic brain injury. Neurol Clin. 2000; 18(4):951–978.Google Scholar
Jellinger, KA. Pathology and pathogenesis of vascular cognitive impairment: a critical update. Front Aging Neurosci. 2013; 5:17.Google Scholar
Kavirajan, H, Schneider, LS. Efficacy and adverse effects of cholinesterase inhibitors and memantine in vascular dementia: a meta-analysis of randomized controlled trails. Lancet Neurol. 2007; 6(9):782–792.Google Scholar
Shepherd, J, Blauw, GJ, Murphy, MB, et al. Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomized controlled trial. Lancet. 2002; 360(9346):1623–1630.Google Scholar
Stone, NJ, Robinson, JG, Lichtenstein, AH, et al. 2013 ACC/AHA guideline on the treatment of blood cholesterol to reduce atherosclerotic cardiovascular risk in adults: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation. 2014; 129(25 Suppl 2):S1–S45.Google Scholar
Cosgrove, J, Alty, JE, Jamieson, S. Cognitive impairment in Parkinson's disease. PGMJ. 2015; 91(1074):212–220.Google Scholar
Vann Jones, SA, O'Brien, JT. The prevalence and incidence of dementia with Lewy bodies: a systematic review of population and clinical studies. Psychol Med. 2014; 44(4):673–683.Google Scholar
Fujimi, K, Sasaki, K, Noda, K, et al. Clinicopathological outline of dementia with Lewy bodies applying the revised criteria: the Hisayama study. Brain Pathol. 2008; 18(3):317–325.Google Scholar
Savica, R, Grossardt, BR, Bower, JH, et al. Incidence of dementia with Lewy bodies and Parkinson disease dementia. JAMA Neurol. 2013; 70(11):1396–1402.Google Scholar
Lewy, FH. Paralysis agitans. In: Lawandowsky, M, ed., Handbuch der Neurologie. Berlin, Springer-Verlag, 1912; 920.Google Scholar
Perry, EK, Marshall, E, Perry, RH, et al. Cholinergic and dopaminergic activities in senile dementia of Lewy body type. Alzheimer Dis Assoc Disord. 1990; 4(2):87–95.Google Scholar
Ballard, C, Piggott, M, Johnson, M, et al. Delusions associated with elevated muscarinic binding in dementia with Lewy bodies. Ann Neurol. 2000; 48(6):868–876.Google Scholar
Piggott, MA, Marshall, EF, Thomas, N, et al. Striatal dopaminergic markers in dementia with Lewy bodies. Alzheimer's and Parkinson's diseases: rostrocaudal distribution. Brain. 1999; 122(Pt 8):1449–1468.Google Scholar
McKeith, IG, Dickson, DW, Lowe, J, et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology. 2005; 65(12):1863–1872.CrossRefGoogle ScholarPubMed
McKeith, IG, Galasko, D, Kosaka, K, et al. Consensus guidelines for the clinical and pathological diagnosis of dementia with Lewy bodies (DLB): report of the Consortium on DLB International Workshop. Neurology. 1996; 47(5):1113–1124.Google Scholar
Weisman, D and McKeith, I. Dementia with Lewy Bodies. Semin Neurol. 2007; 27(1):042–047.Google Scholar
Galvin, JE, Pollack, J, Morris, JC. Clinical phenotype of Parkinson disease dementia. Neurology. 2006; 67(9):1605–1611.Google Scholar
Aarsland, D, Ballard, C, McKeith, I, et al. Comparison of extrapyramidal signs in dementia with Lewy bodies and Parkinson's disease. J Neuropsychiatry Clin Neurosci. 2001; 13(3):374–379.Google Scholar
Ikeda, M, Mori, E, Kosaka, K, et al. Long-term safety and efficacy of donepezil in patients with dementia with Lewy bodies: results from a 52-week, open-label, multicenter extension study. Dement Geriatr Cogn Disord. 2013; 36(3–4):229–241.Google Scholar
Matsunaga, S, Kishi, T, Iwata, N. Memantine for Lewy body disorders: systematic review and meta-analysis. Am J Geriatr Psychiatry. 2015; 23(4):373–383.Google Scholar
Cardarelli, R, Kertesz, A, Knebl, JA. Frontotemporal dementia: a review for primary care physicians. Am Fam Physician. 2010; 82(11):1372–1377.Google Scholar
Johnson, JK, Diehl, J, Mendez, MF, et al. Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol. 2005; 62(2):925–930.Google Scholar
Xiao-dong, P, Xiao-chun, C. Clinic, neuropathology and molecular genetics of frontotemporal dementia: a mini-review. Transl Neurodegener. 2013; 2(1):8.Google Scholar
Sieben, A, Van Langenhove, T, Engelborghs, S, et al. The genetics and neuropathology of frontotemporal lobar degeneration. Acta Neuropathol. 2012; 124(3):353–372.Google Scholar
Ratnavialli, E, Brayne, C, Dawson, K, Hodges, JR. The prevalence of frontotemporal dementia. Neurology. 2002; 58(11):1615–1621.CrossRefGoogle Scholar
Piguet, O, Hornberger, M, Mioishi, E, Hodges, JR. Behavioral-variant frontotemporal dementia: diagnosis, clinical staging, and management. Lancet Neurol. 2011; 10(2):162–172.Google Scholar
Gorno-Tempini, ML, HIllis, AE, Weintraub, S, et al. Classification of primary progressive aphasia and its variants. Neurology. 2011; 76(11):1006–1014.Google Scholar
Johnson, JK, Diehl, J, Mendez, MF, et al. Frontotemporal lobar degeneration: demographic characteristics of 353 patients. Arch Neurol. 2005; 62(6):925–930.Google Scholar
Nardell, M and Tampi, RR. Pharmacological treatments for frontotemporal dementias: a systematic review of randomized controlled trials. Am J Alzheimers Dis Other Demen. 2014; 29(2):123–132.Google Scholar
Warden, V, Hurley, AC, Volicer, L. Development and psychometric evaluation of the Pain Assessment in Advanced Dementia (PAINAD) scale. J Am Med Dir Assoc. 2003; 4(1):9–15.Google Scholar
Hamrick, I, Meyer, F. Perioperative management of delirium and dementia in the geriatric surgical patient. Langenbecks Arch Surg. 2013; 398(7):947–955.Google Scholar
Morrison, RS, Magaziner, J, Gilbert, M, et al. Relationship between pain and opioid analgesics on the development of delirium following hip fracture. J Gerontol A Biol Sci Med Sci. 2003; 58(1):76–81.Google Scholar
References
Fried, TR, Bradley, EH, Towle, VR, Allore, H. Understanding the treatment preferences of seriously ill patients. N Engl J Med. 2002; 346(14):1061–1066.Google Scholar
Crosby, G, Culley, D. Preoperative cognitive assessment of the elderly surgical patient: a call for action. Anesthesiology. 2011; 114:1265–1268.CrossRefGoogle Scholar
American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, 5th edn. Washington, DC, American Psychiatric Association, 2013.Google Scholar
Inouye, S, van Dyck, C, Alessi, C, et al. Clarifying confusion: the confusion assessment method. A new method for detection of delirium. Ann Intern Med. 1990; 113(12):941–948.Google Scholar
Breitbart, W, Rosenfeld, B, Roth, A, et al. The Memorial Delirium Assessment Scale. J Pain Symptom Manage. 1997; 13(3):128–137.Google Scholar
Wei, L, Fearing, M, Sternberg, E, Inouye, SK. The Confusion Assessment Method: a systematic review of current usage. J Am Geriatr Soc. 2008; 56:823–830.Google Scholar
Ely, EW, Margolin, R, Francis, J, et al. Evaluation of delirium in critically ill patients: validation of the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). Crit Care Med. 2001; 29(7):1370–1379.Google Scholar
Inouye, SK, Foreman, MD, Mion, LC, et al. Nurses' recognition of delirium and its symptoms: comparison of nurse and researcher ratings. Arch Int Med. 2001; 161(20):2467–2473.Google Scholar
Yang, FM, Marcantonio, ER, Inouye, SK, et al. Phenomenological subtypes of delirium in older persons: patterns, prevalence, and prognosis. Psychosomatics. 2009; 50(3):248–254.Google Scholar
Stransky, M, Schmidt, C, Ganslmeier, P, et al. Hypoactive delirium after cardiac surgery as an independent risk factor for prolonged mechanical ventilation. J Cardiothor Vasc Anesth. 2011; 25:968–974.Google Scholar
Trzepacz, P, Mittal, D, Torres, R. Validation of the Delirium Rating Scale-Revised-98: comparison with the Delirium Rating Scale and the Cognitive Test for Delirium. J Neuropsychiatry Clin Neurosci. 2001; 13(2):229–242.Google Scholar
Inouye, SK, Kosar, CM, Tommet, D, et al. The CAM-S: development and validation of a new scoring system for delirium severity in 2 cohorts. Ann Intern Med. 2014; 160(8):526–533.Google Scholar
Cole, MM, McCusker, JJ, Dendukuri, NN, Han, LL. The prognostic significance of subsyndromal delirium in elderly medical inpatients. J Am Geriatr Soc. 2003; 51(6):754–760.Google Scholar
Inouye, SK, Leo-Summers, L, Zhang, Y, et al. A chart-based method for identification of delirium: validation compared with interviewer ratings using the Confusion Assessment Method. J Am Geriatr Soc. 2005; 53(2):312–318.Google Scholar
Koster, S, Hensens, AG, Schuurmans, MJ, van der Palen, J. Consequences of delirium after cardiac operations. Ann Thorac Surg. 2012; 93(3):705–711.Google Scholar
Rudolph, JL, Jones, RN, Levkoff, SE, et al. Derivation and validation of a preoperative prediction rule for delirium after cardiac surgery. Circulation. 2009; 119(2):229–236.Google Scholar
Kalisvaart, K, Vreeswijk, R. Risk factors and prediction of postoperative delirium in elderly hip-surgery patients: implementation and validation of a medical risk factor model. J Am Geriatr Soc. 2006; 54:817–822.Google Scholar
Bickel, H, Gradinger, R, Kochs, E, Forstl, H. High risk of cognitive and functional decline after postoperative delirium. Dement Geriatr Cogn Disord. 2008; 26:26–31.Google Scholar
Sieber, F, Zakriya, K, Gottschalk, A, et al. Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair. Mayo Clin Proc. 2010; 85:18–26.Google Scholar
Benoit, AG, Campbell, BI, Tanner, JR, et al. Risk factors and prevalence of perioperative cognitive dysfunction in abdominal aneurysm patients. J Vasc Surg. 2005; 42(5):884–890.Google Scholar
Ansaloni, L, Catena, F, Chattat, R, et al. Risk factors and incidence of postoperative delirium in elderly patients after elective and emergency surgery. Br J Surg. 2010; 97:273–280.Google Scholar
Brown, CH IV, Dowdy, D. Risk factors for delirium: are systematic reviews enough? Crit Care Med. 2015; 43(1):232–233.Google Scholar
Albrecht, JS, Marcantonio, ER, Roffey, DM, et al. Stability of postoperative delirium psychomotor subtypes in individuals with hip fracture. J Am Geriatr Soc. 2015; 63:970–976.Google Scholar
Inouye, S, Westendorp, R, Sazynski, J. Delirium in elderly people. Lancet. 2014; 383:911–922.Google Scholar
Marcantonio, ER, Goldman, L, Mangione, CM, et al. A clinical prediction rule for delirium after elective noncardiac surgery. JAMA. 1994; 271(2):134–139.Google Scholar
Leung, JM, Tsai, TL, Sands, LP. Preoperative frailty in older surgical patients is associated with early postoperative delirium. Anesth Analg. 2011; 112(5):1199–1201.Google Scholar
Jung, P, Pereira, M, Hiebert, B, et al. The impact of frailty on postoperative delirium in cardiac surgery patients. J Thorac Cardiovasc Surg. 2015; 149:869–875.Google Scholar
Hshieh, TT, Fong, TG, Marcantonio, ER, Inouye, SK. Cholinergic deficiency hypothesis in delirium: a synthesis of current evidence. J Gerontol A Biol Sci Med Sci. 2008; 63(7):764–772.Google Scholar
Dantzer, R, O'Connor, JC, Freund, GG, Johnson, RW, Kelley, KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci. 2008; 9(1):46–56.Google Scholar
van Munster, BC, Aronica, E, Zwinderman, AH, et al. Neuroinflammation in delirium: a postmortem case-control study. Rejuv Res. 2011; 14(6):615–622.Google Scholar
Fong, TG, Bogardus, ST, Daftary, A, et al. Cerebral perfusion changes in older delirious patients using 99mTc HMPAO SPECT. J Gerontol A Biol Sci Med Sci. 2006; 61(12):1294–1299.Google Scholar
Hori, D, Brown, C, Ono, M, et al. Arterial pressure above the upper cerebral autoregulation limit during cardiopulmonary bypass is associated with postoperative delirium. Br J Anaesth. 2014; 113(6):1009–1017.CrossRefGoogle ScholarPubMed
Acharya, NK, Goldwaser, EL, Forsberg, MM, et al. Sevoflurane and isoflurane induce structural changes in brain vascular endothelial cells and increase blood–brain barrier permeability: possible link to postoperative delirium and cognitive decline. Brain Res. 2015; 1620:29–41.Google Scholar
Gottesman, R, Grega, M, Bailey, M, et al. Delirium after coronary artery bypass graft surgery and late mortality. Ann Neurol. 2010; 67:338–344.Google Scholar
Ely, EW, Shintani, A, Truman, B, et al. Delirium as a predictor of mortality in mechanically ventilated patients in the intensive care unit. JAMA. 2004; 291(14):1753–1762.Google Scholar
Pisani, MA, Kong, SY, Kasl, SV, et al. Days of delirium are associated with 1-year mortality in an older intensive care unit population. Am J Respir Crit Care Med. 2009; 180:1092–1097.Google Scholar
Martin, B, Buth, K, Arora, R, Baskett, R. Delirium as a predictor of sepsis in postcoronary artery bypass grafting patients: a retrospective cohort study. Crit Care. 2010; 14:R171.Google Scholar
House, A, Holmes, J. Occurrence and outcome of delirium in medical in-patients: a systematic literature review. Age Ageing. 2006; 35:350–364.Google Scholar
Saczynski, JS, Marcantonio, ER, Quach, L, et al. Cognitive trajectories after postoperative delirium. N Engl J Med. 2012; 367(1):30–39.Google Scholar
MacLullich, AM, Beaglehole, A, Hall, RJ, Meagher, DJ. Delirium and long-term cognitive impairment. Int Rev Psychiatry. 2009; 21(1):30–42.Google Scholar
Gottschalk, A, Hubbs, J, Vikani, AR, Gottschalk, LB, Sieber, FE. The impact of incident postoperative delirium on survival of elderly patients after surgery for hip fracture repair. Anesth Analg. 2015; 121(5):1336–1343.Google Scholar
Sieber, F, Barnett, S. Preventing postoperative complications in the elderly. Anesthesiol Clin. 2011; 29:83–97.Google Scholar
American Geriatrics Society Expert Panel on Postoperative Delirium in Older Adults. American Geriatrics Society abstracted clinical practice guideline for postoperative delirium in older adults. J Am Geriatr Soc. 2015; 63:142–150.Google Scholar
Barr, J, Fraser, GL, Puntillo, K, et al. Clinical practice guidelines for the management of pain, agitation, and delirium in adult patients in the intensive care unit. Crit Care Med. 2013; 41(1):263–306.Google Scholar
Young, J, Murthy, L, Westby, M, et al. Diagnosis, prevention, and management of delirium: summary of NICE guidance. BMJ. 2010; 341:c3704.Google Scholar
Inouye, S, Bogardus, S, Charpentier, P, et al. A multicomponent intervention to prevent delirium in hospitalized older patients. NEJM. 1999; 340:669–676.Google Scholar
Lundström, M, Olofsson, B, Stenvall, M, et al. Postoperative delirium in old patients with femoral neck fracture: a randomized intervention study. Aging Clin Exp Res. 2007; 19(3):178–186.Google Scholar
Chen, C, Lin, MT, Tien, YW, et al. Modified Hospital Elder Life Program: effects on abdominal surgery patients. J Am Coll Surg. 2011; 213(2):245–252.Google Scholar
Marcantonio, E, Flacker, J, Wright, R, Resnick, N. Reducing delirium after hip fracture: a randomized trial. J Am Geriatr Soc. 2001; 49:516–522.Google Scholar
Lynch, E, Lazor, M, Gellis, J, et al. The impact of postoperative pain on the development of postoperative delirium. Anesth Analg. 1998; 86:781–785.Google Scholar
Vaurio, LE, Sands, LP, Wang, Y, Mullen, EA, Leung, JM. Postoperative delirium: the importance of pain and pain management. Anesth Analg. 2006; 102(4):1267–1273.Google Scholar
Krenk, L, Rasmussen, LS, Hansen, TB, et al. Delirium after fast-track hip and knee arthroplasty. Br J Anaesth. 2012; 108:607–611.Google Scholar
Leung, JM, Sands, LP, Rico, M, et al. Pilot clinical trial of gabapentin to decrease postoperative delirium in older patients. Neurology. 2006; 67(7):1251–1253.Google Scholar
Kinjo, S, Lim, E, Sands, LP, Bozic, KJ, Leung, JM. Does using a femoral nerve block for total knee replacement decrease postoperative delirium? BMC Anesthesiol. 2012; 12(1):4.Google Scholar
Mouzopoulos, G, Vasiliadis, G, Lasanianos, N, et al. Fascia iliaca block prophylaxis for hip fracture patients at risk for delirium: a randomized placebo-controlled study. J Orthopaed Traumatol. 2009; 10(3):127–133.Google Scholar
Marcantonio, ER, Juarez, G, Goldman, L, et al. The relationship of postoperative delirium with psychoactive medications. JAMA. 1994; 272(19):1518–1522.Google Scholar
Fong, HK, Sands, LP, Leung, JM. The role of postoperative analgesia in delirium and cognitive decline in elderly patients: a systematic review. Anesth Analg. 2006; 102(4):1255–1266.Google Scholar
Riker, R, Shehabi, Y, Bokesch, P, et al. Dexmedetomidine vs midazolam for sedation of critically ill patients. JAMA. 2009; 301:489–499.Google Scholar
Pandharipande, P, Pun, B, Herr, D, et al. Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial. JAMA. 2007; 298(22):2644–2653.Google Scholar
Maldonado, JR, Wysong, A, van der Starre, P, et al. Dexmedetomidine and the reduction of postoperative delirium after cardiac surgery. Psychosomatics. 2009; 50(3):206–217.Google Scholar
Hogan, D. Revisiting the O complex: urinary incontinence, delirium and polypharmacy in elderly patients. Can Med Assoc J. 1997; 157:1071–1077.Google Scholar
The American Geriatrics Society 2012 Beers Criteria Update Expert Panel. American Geriatrics Society Updated Beers Criteria for Potentially Inappropriate Medication Use in Older Adults. J Am Geriatr Soc. 2012; 60(4):616–631.Google Scholar
Hakim, S, Othman, A, Naoum, D. Early treatment with risperidone for subsyndromal delirium after on-pump cardiac surgery in the elderly. Anesthesiology. 2012; 116:987–997.Google Scholar
Kalisvaart, K, De Jonghe, J, Bogaards, M. Haloperidol prophylaxis for elderly hip-surgery patients at risk for delirium: a randomized placebo-controlled study. J Am Geriatr Soc. 2005; 53:1658–1666.Google Scholar
Sauër, A-MC, Slooter, A, Veldhuijzen, D, et al. Intraoperative dexamethasone and delirium after cardiac surgery. Anesth Analg. 2014; 119(5):1046–1052.Google Scholar
Gamberini, M, Bolliger, D, Lurati Buse, GA, et al. Rivastigmine for the prevention of postoperative delirium in elderly patients undergoing elective cardiac surgery: a randomized controlled trial. Crit Care Med. 2009; 37(5):1762–1768.Google Scholar
van Eijk, MD, Roes, K, Honing, M, et al. Effect of rivastigmine as an adjunct to usual care with haloperidol on duration of delirium and mortality in critically ill patients: a multicentre, double-blind, placebo-controlled randomised trial. Lancet. 2010; 376(9755):1829–1837.Google Scholar
Fava, M. Prospective studies of adverse events related to antidepressant discontinuation. J Clin Psychiatry. 2006; 67(Suppl 4):14–21.Google Scholar
Xie, Z, Dong, Y, Maeda, U, Alfille, P, Culley, DJ. The common inhalation anesthetic isoflurane induces apoptosis and increases amyloid β protein levels. Anesthesiology. 2006; 104:988–994.Google Scholar
Zhang, B, Dong, Y, Zhang, G, et al. The inhalation anesthetic desflurane induces caspase activation and increases amyloid β-protein levels under hypoxic conditions. J Biol Chem. 2008; 283(18):11866–11875.Google Scholar
Zhang, Y, Dong, Y, Wu, X, et al. The mitochondrial pathway of anesthetic isoflurane-induced apoptosis. J Biol Chem. 2010; 285:4025–4037.Google Scholar
Mason, SE, Noel-Storr, A, Ritchie, CW. The impact of general and regional anesthesia on the incidence of postoperative cognitive dysfunction and postoperative delirium: a systematic review with meta-analysis. J Alz Dis. 2010; 22(Suppl 3):67–79.Google Scholar
Marcantonio, ER, Goldman, L, Orav, EJ, Cook, EF, Lee, TH. The association of intraoperative factors with the development of postoperative delirium. Am J Med. 1998; 105(5):380–384.Google Scholar
Parker, MJ, Handoll, HH, Griffiths, R. Anaesthesia for hip fracture surgery in adults. Cochrane Database Syst Rev. 2004(4):CD000521.Google Scholar
Radtke, FM, Franck, M, Lendner, J, et al. Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction. Br J Anaesth. 2013; 110(Suppl 1):i98–i105.Google Scholar
Chan, MT, Cheng, BC, Lee, TM, Gin, T; Coda Trial Group. BIS-guided anesthesia decreases postoperative delirium and cognitive decline. J Neurosurg Anesthesiol. 2013; 25:33–42.Google Scholar
Whitlock, EL, Torres, BA, Lin, N, et al. Postoperative delirium in a substudy of cardiothoracic surgical patients in the BAG-RECALL clinical trial. Anesth Analg. 2014; 118:809–817.Google Scholar
Yocum, GT, Gaudet, JG, Teverbaugh, LA, et al. Neurocognitive performance in hypertensive patients after spine surgery. Anesthesiology. 2009; 110(2):254–261.Google Scholar
Patti, R, Saitta, M, Cusumano, G, Termine, G, Di Vita, G. Risk factors for postoperative delirium after colorectal surgery for carcinoma. Eur J Oncol Nurs. 2011; 15(5):519–523.Google Scholar
Williams-Russo, P, Sharrock, NE, Mattis, S, Szatrowski, TP, Charlson, ME. Cognitive effects after epidural vs general anesthesia in older adults. A randomized trial. JAMA. 1995; 274(1):44–50.Google Scholar
Moller, J, Cluitmans, P, Rasmussen, L, et al. Long-term postoperative cognitive dysfunction in the elderly: ISPOCD1 study. Lancet. 1998; 351:857–861.Google Scholar
Bijker, JB, van Klei, WA, Kappen, TH, et al. Incidence of intraoperative hypotension as a function of the chosen definition: literature definitions applied to a retrospective cohort using automated data collection. Anesthesiology. 2007; 107(2):213–220.Google Scholar
Joshi, B, Ono, M, Brown, C, et al. Predicting the limits of cerebral autoregulation during cardiopulmonary bypass. Anesth Analg. 2012; 114(3):503–510.Google Scholar
Wang, NY, Hirao, A, Sieber, F. Association between intraoperative blood pressure and postoperative delirium in elderly hip fracture patients. PLoS One. 2015; 10(4):e0123892.Google Scholar
Gruber-Baldini, AL, Marcantonio, E, Orwig, D, et al. Delirium outcomes in a randomized trial of blood transfusion thresholds in hospitalized older adults with hip fracture. J Am Geriatr Soc. 2013; 61(8):1286–1295.Google Scholar
Carson, JL, Terrin, ML, Noveck, H. Liberal or restrictive transfusion in high-risk patients after hip surgery. N Engl J Med. 2011; 365:2453–2462.Google Scholar
Monk, TG, Price, CC. Postoperative cognitive disorders. Curr Opin Crit Care. 2011; 17(4):376–381.Google Scholar
Rasmussen, LS, Larsen, K, Houx, P, et al. The assessment of postoperative cognitive function. Acta Anaesthesiol Scand. 2001; 45(3):275–289.Google Scholar
Krenk, L, Rasmussen, LS. Postoperative delirium and postoperative cognitive dysfunction in the elderly: what are the differences? Minerva Anestesiol. 2011; 77(7):742–749.Google Scholar
McDonagh, DL, Mathew, JP, White, WD, et al. Cognitive function after major noncardiac surgery, apolipoprotein E4 genotype, and biomarkers of brain injury. Anesthesiology. 2010; 112(4):852–859.Google Scholar
Newman, MF, Kirchner, JL, Phillips-Bute, B, et al. Longitudinal assessment of neurocognitive function after coronary-artery bypass surgery. NEJM. 2001; 344(6):395–402.Google Scholar
van Dijk, D, Spoor, M, Hijman, R, et al. Cognitive and cardiac outcomes 5 years after off-pump vs on-pump coronary artery bypass graft surgery. JAMA. 2007; 297(7):701–708.Google Scholar
Monk, TG, Weldon, BC, Garvan, CW, et al. Predictors of cognitive dysfunction after major noncardiac surgery. Anesthesiology. 2008; 108(1):18–30.Google Scholar
Ottens, TH, Dieleman, JM, Sauer, AM, et al. Effects of dexamethasone on cognitive decline after cardiac surgery: a randomized clinical trial. Anesthesiology. 2014; 121(3):492–500.Google Scholar
Silbert, B, Evered, L, Scott, DA, et al. Preexisting cognitive impairment is associated with postoperative cognitive dysfunction after hip joint replacement surgery. Anesthesiology. 2015; 122(6):1224–1234.Google Scholar
Quinlan, N, Rudolph, JL. Postoperative delirium and functional decline after noncardiac surgery. J Am Geriatr Soc. 2011; 59(Suppl 2):S301–S304.Google Scholar
Abildstrom, H, Rasmussen, LS, Rentowl, P, et al. Cognitive dysfunction 1-2 years after non-cardiac surgery in the elderly. ISPOCD group. International Study of PostOperative Cognitive Dysfunction. Acta Anaesthesiol Scand. 2000; 44(10):1246–1251.Google Scholar
Bruce, KM, Yelland, GW, Smith, JA, Robinson, SR. Recovery of cognitive function after coronary artery bypass graft operations. Ann Thorac Surg. 2013; 95(4):1306–1313.Google Scholar
Cormack, F, Shipolini, A, Awad, WI, et al. A meta-analysis of cognitive outcome following coronary artery bypass graft surgery. Neurosci Biobehav Rev. 2012; 36(9):2118–2129.Google Scholar
Selnes, OA, Gottesman, RF, Grega, MA, et al. Cognitive and neurologic outcomes after coronary-artery bypass surgery. N Engl J Med. 2012; 366(3):250–257.Google Scholar
Papaioannou, A, Fraidakis, O, Michaloudis, D, Balalis, C, Askitopoulou, H. The impact of the type of anaesthesia on cognitive status and delirium during the first postoperative days in elderly patients. Eur J Anesthesiol. 2005; 22(7):492–499.CrossRefGoogle ScholarPubMed
Ballard, C, Jones, E, Gauge, N, et al. Optimised anaesthesia to reduce post operative cognitive decline (POCD) in older patients undergoing elective surgery, a randomised controlled trial. PLoS One. 2012; 7(6):e37410.Google Scholar
Nadelson, MR, Sanders, RD, Avidan, MS. Perioperative cognitive trajectory in adults. Br J Anesth. 2014; 112(3):440–451.Google Scholar
Silbert, B, Evered, L, Scott, DA. Cognitive decline in the elderly: is anaesthesia implicated? Best Pract Res Clin Anaesthesiol. 2011; 25(3):379–393.Google Scholar
Evered, L, Scott, DA, Silbert, B, Maruff, P. Postoperative cognitive dysfunction is independent of type of surgery and anesthetic. Anesth Analg. 2011; 112(5):1179–1185.Google Scholar
Hlatky, MA, Bacon, C, Boothroyd, D, et al. Cognitive function 5 years after randomization to coronary angioplasty or coronary artery bypass graft surgery. Circulation. 1997; 96(9 Suppl):II-11–14; discussion II-15.Google Scholar
Lal, BK, Younes, M, Cruz, G, et al. Cognitive changes after surgery vs stenting for carotid artery stenosis. J Vascul Surg. 2011; 54(3):691–698.Google Scholar
Selnes, OA, Grega, MA, Bailey, MM, et al. Neurocognitive outcomes 3 years after coronary artery bypass graft surgery: a controlled study. Ann Thorac Surg. 2007; 84(6):1885–1896.Google Scholar
Selnes, OA, Grega, MA, Bailey, MM, et al. Cognition 6 years after surgical or medical therapy for coronary artery disease. Ann Neurol. 2008; 63(5):581–590.Google Scholar
Selnes, OA, Grega, MA, Bailey, MM, et al. Do management strategies for coronary artery disease influence 6-year cognitive outcomes? Ann Thor Surg. 2009; 88(2):445–454.Google Scholar
Shroyer, AL, Grover, FL, Hattler, B, et al. On-pump versus off-pump coronary-artery bypass surgery. N Engl J Med. 2009; 361(19):1827–1837.Google Scholar
Silbert, BS, Evered, LA, Scott, DA. Incidence of postoperative cognitive dysfunction after general or spinal anaesthesia for extracorporeal shock wave lithotripsy. Br J Anaesth. 2014; 113:784–791.Google Scholar
Rasmussen, LS, Johnson, T, Kuipers, HM, et al. Does anaesthesia cause postoperative cognitive dysfunction? A randomised study of regional versus general anaesthesia in 438 elderly patients. Acta Anaesthesiol Scand. 2003; 47(3):260–266.Google Scholar
Farag, E, Chelune, GJ, Schubert, A, Mascha, EJ. Is depth of anesthesia, as assessed by the Bispectral Index, related to postoperative cognitive dysfunction and recovery? Anesth Analg. 2006; 103(3):633–640.Google Scholar
Avidan, MS, Searleman, AC, Storandt, M, et al. Long-term cognitive decline in older subjects was not attributable to noncardiac surgery or major illness. Anesthesiology. 2009; 111(5):964–970.Google Scholar
Neufeld, KJ, Leoutsakos, JM, Sieber, FE, et al. Outcomes of early delirium diagnosis after general anesthesia in the elderly. Anesth Analg. 2013; 117(2):471–478.Google Scholar
Abelha, FJ, Luis, C, Veiga, D, et al. Outcome and quality of life in patients with postoperative delirium during an ICU stay following major surgery. Crit Care. 2013; 17(5):R257.Google Scholar
Pandharipande, PP, Girard, TD, Jackson, JC, et al. Long-term cognitive impairment after critical illness. N Engl J Med. 2013; 369(14):1306–1316.Google Scholar
Steinmetz, J, Christensen, KB, Lund, T, et al. Long-term consequences of postoperative cognitive dysfunction. Anesthesiology. 2009; 110(3):548–555.Google Scholar
Steinmetz, J, Siersma, V, Kessing, LV, et al. Is postoperative cognitive dysfunction a risk factor for dementia? A cohort follow-up study. Br J Anaesth. 2013; 110(Suppl 1):i92–i97.Google Scholar
AGS/NIA Delirium Conference Writing Group, Planning Committee and Faculty. The American Geriatrics Society/National Institute on Aging Bedside-to-Bench Conference: research agenda on delirium in older adults. J Am Geriatr Soc. 2015; 63(5):843–852.Google Scholar
Anderson, DJ, Podgorny, K, Berrios-Torres, SI, et al. Strategies to prevent surgical site infections in acute care hospitals: 2014 update. Infect Control Hosp Epidemiol. 2014; 35(Suppl 2):S66–S88.Google Scholar
References
Klotz, U. Pharmacokinetics and drug metabolism in the elderly. Drug Metab Rev. 2009; 41(2):67–76.Google Scholar
Deiner, S, Silverstein, JH. Anesthesia for geriatric patients. Minerva Anestesiol. 2011; 77(2):180–189.Google Scholar
Sharma, A, Mucino, MJ, Ronco, C. Renal functional reserve and renal recovery after acute kidney injury. Nephron Clin Pract. 2014; 127(1-4):94–100.Google Scholar
2014 National Population Projections: summary tables. 2014; Available at: www.census.gov/population/projections/data/national/2014/summarytables.html. (Accessed July 5, 2017).Google Scholar
Tonner, PH, Kampen, J, Scholz, J. Pathophysiological changes in the elderly. Best Pract Res Clin Anaesthesiol. 2003; 17(2):163–177.CrossRefGoogle ScholarPubMed
McLachlan, AJ, Bath, S, Naganathan, V, et al. Clinical pharmacology of analgesic medicines in older people: impact of frailty and cognitive impairment. Br J Clin Pharmacol. 2011; 71(3):351–364.Google Scholar
Grassi, M, Petraccia, L, Mennuni, G, et al. Changes, functional disorders, and diseases in the gastrointestinal tract of elderly. Nutr Hosp. 2011; 26(4):659–668.Google Scholar
Steele, AC, Meechan, JG. Pharmacology and the elderly. Dent Update. 2010; 37(10):666–8, 670–2.Google Scholar
Hilmer, SN, McLachlan, AJ, Le Couteur, DG. Clinical pharmacology in the geriatric patient. Fundam Clin Pharmacol. 2007; 21(3):217–230.Google Scholar
Butler, JM, Begg, EJ. Free drug metabolic clearance in elderly people. Clin Pharmacokinet. 2008; 47(5):297–321.Google Scholar
Turnheim, K. When drug therapy gets old: pharmacokinetics and pharmacodynamics in the elderly. Exp Gerontol. 2003; 38(8):843–853.Google Scholar
Vuyk, J. Pharmacodynamics in the elderly. Best Pract Res Clin Anaesthesiol. 2003; 17(2):207–218.Google Scholar
Kazama, T, Ikeda, K, Morita, K, et al. Relation between initial blood distribution volume and propofol induction dose requirement. Anesthesiology. 2001; 94(2):205–210.Google Scholar
Polasek, TM, Patel, F, Jensen, BP, et al. Predicted metabolic drug clearance with increasing adult age. Br J Clin Pharmacol. 2013; 75(4):1019–1028.Google Scholar
Colloca, G, Santoro, M, Gambassi, G. Age-related physiologic changes and perioperative management of elderly patients. Surg Oncol. 2010; 19(3):124–130.Google Scholar
Lamb, EJ, O'Riordan, SE, Delaney, MP. Kidney function in older people: pathology, assessment and management. Clin Chim Acta. 2003; 334(1–2):25–40.Google Scholar
Buemi, M, Nostro, L, Aloisi, C, et al. Kidney aging: from phenotype to genetics. Rejuvenation Res. 2005; 8(2):101–109.Google Scholar
Giannelli, SV, Patel, KV, Windham, BG, et al. Magnitude of underascertainment of impaired kidney function in older adults with normal serum creatinine. J Am Geriatr Soc. 2007; 55(6):816–823.Google Scholar
El-Sharkawy, AM, Sahota, O, Maughan, RJ, Lobo, DN. The pathophysiology of fluid and electrolyte balance in the older adult surgical patient. Clin Nutr. 2014; 33(1):6–13.Google Scholar
Allison, SP, Lobo, DN. Fluid and electrolytes in the elderly. Curr Opin Clin Nutr Metab Care. 2004; 7(1):27–33.Google Scholar
Ferenczi, E, Datta, SS, Chopada, A. Intravenous fluid administration in elderly patients at a London hospital: a two-part audit encompassing ward-based fluid monitoring and prescribing practice by doctors. Int J Surg. 2007; 5(6):408–412.Google Scholar
Luckey, AE, Parsa, CJ. Fluid and electrolytes in the aged. Arch Surg. 2003; 138(10):1055–1060.Google Scholar
Keita, H, Tubach, F, Maalouli, J, Desmonts, JM, Mantz, J. Age-adapted morphine titration produces equivalent analgesia and adverse effects in younger and older patients. Eur J Anaesthesiol. 2008; 25(5):352–356.Google Scholar
Paolisso, G. Pathophysiology of diabetes in elderly people. Acta Biomed. 2010; 81(Suppl 1):47–53.Google Scholar
Meneilly, GS. Pathophysiology of type 2 diabetes in the elderly. Clin Geriatr Med. 1999; 15(2):239–253.Google Scholar
Geloneze, B, de Oliveira Mda, S, Vasques, AC, Novaes, FS, Pareja, JC, Tambascia, MA. Impaired incretin secretion and pancreatic dysfunction with older age and diabetes. Metabolism. 2014; 63(7):922–929.Google Scholar
Nin, V, Chini, CC, Escande, C, Capellini, V, Chini, EN. Deleted in breast cancer 1 (DBC1) protein regulates hepatic gluconeogenesis. J Biol Chem. 2014; 289(9):5518–5527.Google Scholar
References
Clegg, A, Young, J, Iliffe, S, Rikkert, MO, Rockwood, K. Frailty in elderly people. Lancet. 2013; 381(9868):752–762.Google Scholar
Makary, MA, Segev, DL, Pronovost, PJ, et al. Frailty as a predictor of surgical outcomes in older patients. J Am Coll Surg. 2010; 210(6):901–908.Google Scholar
Kristjansson, SR, Nesbakken, A, Jordhoy, MS, et al. Comprehensive geriatric assessment can predict complications in elderly patients after elective surgery for colorectal cancer: a prospective observational cohort study. Crit Rev Oncol Hematol. 2010; 76(3):208–217.Google Scholar
Green, P, Woglom, AE, Genereux, P, et al. The impact of frailty status on survival after transcatheter aortic valve replacement in older adults with severe aortic stenosis: a single-center experience. JACC Cardiovasc Interv. 2012; 5(9):974–981.Google Scholar
Schoenenberger, AW, Stortecky, S, Neumann, S, et al. Predictors of functional decline in elderly patients undergoing transcatheter aortic valve implantation. Eur Heart J. 2013; 34(9):684–692.Google Scholar
Kim, CA, Rasania, SP, Afilalo, J, et al. Functional status and quality of life after transcatheter aortic valve replacement: a systematic review. Ann Intern Med. 2014; 160(4):243–254.Google Scholar
Kim, SW, Han, HS, Jung, HW, et al. Multidimensional frailty score for the prediction of postoperative mortality risk. JAMA Surg. 2014; 149(7):633–640.Google Scholar
Gill, TM, Gahbauer, EA, Allore, HG, Han, L. Transitions between frailty states among community-living older persons. Arch Intern Med. 2006; 166(4):418–423.Google Scholar
Ellis, G, Whitehead, MA, Robinson, D, O'Neill, D, Langhorne, P. Comprehensive geriatric assessment for older adults admitted to hospital: meta-analysis of randomised controlled trials. BMJ. 2011; 343:d6553.Google Scholar
Beswick, AD, Rees, K, Dieppe, P, et al. Complex interventions to improve physical function and maintain independent living in elderly people: a systematic review and meta-analysis. Lancet. 2008; 371(9614):725–735.Google Scholar
Stuck, AE, Egger, M, Hammer, A, Minder, CE, Beck, JC. Home visits to prevent nursing home admission and functional decline in elderly people: systematic review and meta-regression analysis. JAMA. 2002; 287(8):1022–1028.Google Scholar
de Vries, NM, van Ravensberg, CD, Hobbelen, JS, et al. Effects of physical exercise therapy on mobility, physical functioning, physical activity and quality of life in community-dwelling older adults with impaired mobility, physical disability and/or multi-morbidity: a meta-analysis. Ageing Res Rev. 2012; 11(1):136–149.Google Scholar
Forster, A, Lambley, R, Hardy, J, et al. Rehabilitation for older people in long-term care. Cochrane Database Syst Rev. 2009(1):CD004294.Google Scholar
Rockwood, K, Mitnitski, A. Frailty in relation to the accumulation of deficits. J Gerontol A Biol Sci Med Sci. 2007; 62(7):722–727.Google Scholar
Fried, LP, Tangen, CM, Walston, J, et al. Frailty in older adults: evidence for a phenotype. J Gerontol A Biol Sci Med Sci. 2001; 56(3):M146–M156.Google Scholar
Morley, JE, Vellas, B, van Kan, GA, et al. Frailty consensus: a call to action. J Am Med Dir Assoc. 2013; 14(6):392–397.Google Scholar
Rockwood, K, Andrew, M, Mitnitski, A. A comparison of two approaches to measuring frailty in elderly people. J Gerontol A Biol Sci Med Sci. 2007; 62(7):738–743.Google Scholar
Woo, J, Leung, J, Morley, JE. Comparison of frailty indicators based on clinical phenotype and the multiple deficit approach in predicting mortality and physical limitation. J Am Geriatr Soc. 2012; 60(8):1478–1486.Google Scholar
Ensrud, KE, Ewing, SK, Taylor, BC, et al. Comparison of 2 frailty indexes for prediction of falls, disability, fractures, and death in older women. Arch Intern Med. 2008; 168(4):382–389.Google Scholar
Robinson, TN, Wu, DS, Sauaia, A, et al. Slower walking speed forecasts increased postoperative morbidity and 1-year mortality across surgical specialties. Ann Surg. 2013; 258(4):582–588; discussion 588–590.Google Scholar
Beggs, T, Sepehri, A, Szwajcer, A, Tangri, N, Arora, RC. Frailty and perioperative outcomes: a narrative review. Can J Anaesth. 2015; 62(2):143–157.Google Scholar
Sepehri, A, Beggs, T, Hassan, A, et al. The impact of frailty on outcomes after cardiac surgery: a systematic review. J Thorac Cardiovasc Surg. 2014; 148(6):3110–3117.Google Scholar
Partridge, JS, Harari, D, Dhesi, JK. Frailty in the older surgical patient: a review. Age Ageing. 2012; 41(2):142–147.Google Scholar
Hubbard, RE, Story, DA. Patient frailty: the elephant in the operating room. Anaesthesia. 2014; 69(Suppl 1):26–34.Google Scholar
Podsiadlo, D, Richardson, S. The timed “Up & Go”: a test of basic functional mobility for frail elderly persons. J Am Geriatr Soc. 1991; 39(2):142–148.Google Scholar
Afilalo, J, Eisenberg, MJ, Morin, JF, et al. Gait speed as an incremental predictor of mortality and major morbidity in elderly patients undergoing cardiac surgery. J Am Coll Cardiol. 2010; 56(20):1668–1676.Google Scholar
Afilalo, J, Mottillo, S, Eisenberg, MJ, et al. Addition of frailty and disability to cardiac surgery risk scores identifies elderly patients at high risk of mortality or major morbidity. Circ Cardiovasc Qual Outcomes. 2012; 5(2):222–228.Google Scholar
de Arenaza, DP, Pepper, J, Lees, B, et al. Preoperative 6-minute walk test adds prognostic information to Euroscore in patients undergoing aortic valve replacement. Heart 2010; 96(2):113–117.Google Scholar
Mok, M, Nombela-Franco, L, Urena, M, et al. Prognostic value of exercise capacity as evaluated by the 6-minute walk test in patients undergoing transcatheter aortic valve implantation. J Am Coll Cardiol. 2013; 61(8):897–898.Google Scholar
Puls, M, Sobisiak, B, Bleckmann, A, et al. Impact of frailty on short- and long-term morbidity and mortality after transcatheter aortic valve implantation: risk assessment by Katz Index of activities of daily living. EuroIntervention 2014; 10(5):609–619.Google Scholar
Savva, GM, Donoghue, OA, Horgan, F, O'Regan, C, Cronin, H, Kenny, RA. Using timed up-and-go to identify frail members of the older population. J Gerontol A Biol Sci Med Sci. 2013; 68(4):441–446.Google Scholar
Kristjansson, SR, Ronning, B, Hurria, A, et al. A comparison of two pre-operative frailty measures in older surgical cancer patients. J Geriatr Oncol. 2012; 3:1–7.Google Scholar
Partridge, JS, Harari, D, Martin, FC, Dhesi, JK. The impact of pre-operative comprehensive geriatric assessment on postoperative outcomes in older patients undergoing scheduled surgery: a systematic review. Anaesthesia. 2014; 69(Suppl 1):8–16.Google Scholar
Chow, WB, Rosenthal, RA, Merkow, RP, et al. Optimal preoperative assessment of the geriatric surgical patient: a best practices guideline from the American College of Surgeons National Surgical Quality Improvement Program and the American Geriatrics Society. J Am Coll Surg. 2012; 215(4):453–466.Google Scholar
Luger, TJ, Kammerlander, C, Gosch, M, et al. Neuroaxial versus general anaesthesia in geriatric patients for hip fracture surgery: does it matter? Osteoporos Int. 2010; 21(Suppl 4):S555–572.Google Scholar
Macfarlane, AJ, Prasad, GA, Chan, VW, Brull, R. Does regional anesthesia improve outcome after total knee arthroplasty? Clin Orthop Relat Res. 2009; 467(9):2379–2402.CrossRefGoogle ScholarPubMed
Bryson, GL, Wyand, A. Evidence-based clinical update: general anesthesia and the risk of delirium and postoperative cognitive dysfunction. Can J Anaesth. 2006; 53(7):669–677.Google Scholar
Newman, S, Stygall, J, Hirani, S, Shaefi, S, Maze, M. Postoperative cognitive dysfunction after noncardiac surgery: a systematic review. Anesthesiology. 2007; 106(3):572–590.Google Scholar
Radtke, FM, Franck, M, Lendner, J, et al. Monitoring depth of anaesthesia in a randomized trial decreases the rate of postoperative delirium but not postoperative cognitive dysfunction. Br J Anaesth. 2013; 110(Suppl 1):i98–i105.Google Scholar
Chan, MT, Cheng, BC, Lee, TM, Gin, T, Group, CT. BIS-guided anesthesia decreases postoperative delirium and cognitive decline. J Neurosurg Anesth. 2013; 25(1):33–42.Google Scholar
Sieber, FE, Zakriya, KJ, Gottschalk, A, et al. Sedation depth during spinal anesthesia and the development of postoperative delirium in elderly patients undergoing hip fracture repair. Mayo Clin Proc. 2010; 85(1):18–26.Google Scholar
Nielsen, PR, Jorgensen, LD, Dahl, B, Pedersen, T, Tonnesen, H. Prehabilitation and early rehabilitation after spinal surgery: randomized clinical trial. Clin Rehabil. 2010; 24(2):137–148.Google Scholar
Carli, F, Charlebois, P, Stein, B, et al. Randomized clinical trial of prehabilitation in colorectal surgery. Br J Surg. 2010; 97(8):1187–1197.Google Scholar
Mayo, NE, Feldman, L, Scott, S, et al. Impact of preoperative change in physical function on postoperative recovery: argument supporting prehabilitation for colorectal surgery. Surgery. 2011; 150(3):505–514.Google Scholar
Harari, D, Hopper, A, Dhesi, J, et al. Proactive care of older people undergoing surgery (‘POPS’): designing, embedding, evaluating and funding a comprehensive geriatric assessment service for older elective surgical patients. Age Ageing. 2007; 36(2):190–196.Google Scholar
Chen, CC, Chen, CN, Lai, IR, et al. Effects of a modified Hospital Elder Life Program on frailty in individuals undergoing major elective abdominal surgery. J Am Geriatr Soc. 2014; 62(2):261–268.Google Scholar
Richter, HE, Redden, DT, Duxbury, AS, et al. Pelvic floor surgery in the older woman: enhanced compared with usual preoperative assessment. Obstet Gynecol. 2005; 105(4):800–807.Google Scholar
Grigoryan, KV, Javedan, H, Rudolph, JL. Orthogeriatric care models and outcomes in hip fracture patients: a systematic review and meta-analysis. J Orthop Trauma. 2014; 28(3):e49–e55.Google Scholar
Inouye, SK, Bogardus, ST Jr., Charpentier, PA, et al. A multicomponent intervention to prevent delirium in hospitalized older patients. N Engl J Med. 1999; 340(9):669–676.Google Scholar
Inouye, SK, Bogardus, ST Jr., Baker, DI, Leo-Summers, L, Cooney, LM Jr. The Hospital Elder Life Program: a model of care to prevent cognitive and functional decline in older hospitalized patients. Hospital Elder Life Program. J Am Geriatr Soc. 2000; 48(12):1697–1706.Google Scholar
Gillespie, LD. Preventing falls in older people: the story of a Cochrane review. Cochrane Database Syst Rev. 2013(2):ED000053.Google Scholar
Ewe, SH, Ajmone Marsan, N, Pepi, M, et al. Impact of left ventricular systolic function on clinical and echocardiographic outcomes following transcatheter aortic valve implantation for severe aortic stenosis. Am Heart J. 2010; 160(6):1113–1120.Google Scholar
Dasgupta, M, Rolfson, DB, Stolee, P, Borrie, MJ, Speechley, M. Frailty is associated with postoperative complications in older adults with medical problems. Arch Gerontol Geriatr. 2009; 48(1):78–83.Google Scholar
Robinson, TN, Wu, DS, Pointer, L, et al. Simple frailty score predicts postoperative complications across surgical specialties. Am J Surg. 2013; 206(4):544–550.Google Scholar
Ellis, G, Spiers, M, Coutts, S, Fairburn, P, McCracken, L. Preoperative assessment in the elderly: evaluation of a new clinical service. Scott Med J. 2012; 57(4):212–216.Google Scholar
Li, C, Carli, F, Lee, L, et al. Impact of a trimodal prehabilitation program on functional recovery after colorectal cancer surgery: a pilot study. Surg Endos. 2013; 27(4):1072–1082.Google Scholar